A5089337038- Moringa oleifera research and applications
- Medicinal Plant Research
- Bioactive Compounds and Antitumor Agents
- Diverse Scientific Research Studies
- Agricultural and Biological Research
- Natural product bioactivities and synthesis
- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Bioactive natural compounds
- Natural Antidiabetic Agents Studies
- Traditional and Medicinal Uses of Annonaceae
- SMEs Development and Digital Marketing
- Phytochemistry and Bioactive Compounds
- Phytochemistry and biological activity of medicinal plants
- Hepatitis C virus research
- Food and Agricultural Sciences
- Biological Activity of Diterpenoids and Biflavonoids
- Phytochemistry and Biological Activities
- Polysaccharides and Plant Cell Walls
- Biodiesel Production and Applications
- Blockchain Technology in Education and Learning
- Sunflower and Safflower Cultivation
- Phytochemicals and Medicinal Plants
Airlangga University
2017-2024
Each part of H. annuus plants is traditionally used as medicinal remedies for several diseases, including malaria. Antimalarial activity the leaf and seed has already been observed; however, there no report about antimalarial other parts plants. In this study, we assess in vitro vivo each its mechanism agent against inhibition heme detoxification.To investigate various annuus.Various plant were tested Plasmodium falciparum 3D7 strain (chloroquine-sensitive), P. berghei using Peters' 4-day...
The high morbidity and mortality due to malaria infection worldwide led the demand for new antimalarial drug development, one of which is utilizing herbal medicines as a alternative treatment. This study aims isolate identify compounds from Luvunga sarmentosa root stem by bioassay-guided isolation approach. were extracted, fractionated purified obtain an compound. Compound identification was conducted based on 1H, 13C 2D NMR. LDH assay used test activity against Plasmodium falciparum. A...
Comparative botanical and phytochemical evaluation of Calotropis procera Linn. gigantea RootSharad Srivastava, Adarsh Pratap Singh, A. K. S. Rawat
Bunga Kasumba turate (Carthamus tinctorius Linn) dari suku Asteraceae merupakan tumbuhan obat tradisional etnis Sulawesi Selatan yang secara empiris digunakan dalam pengobatan campak. Ekstrak etanol kasumba memberikan peningkatan aktivitas imunoglobulin G (IgG) dan A (IgA) sangat signifikan. Penelitian menunjukkan ekstrak bunga C. Tinctorius L memiliki potensi sebagai antimalaria in vitro dengan nilai IC50 sebesar 1,06 µg/ml. Sampel L. kering sebanyak 3 Kg dicacah hingga menjadi serbuk 870...
Cassia siamea leaf has been proven in vitro and vivo to have a strong antimalarial activity with Cassiarin A as its active compound. To obtain source of C. medicinal plant high level compound (Cassiarin A), valid method for determining is needed. For this reason, research conducts the validation content determination using thin-layer chromatography (TLC) densitometry which includes selectivity ( R s), linearity (r), accuracy, precision, limit detection (LOD), quantification (LOQ). was...
Background: Malaria is the most important parasitic disease. control which depends on specific chemotherapy now complicated by resistance of Plasmodium falciparum to commonly available antimalarial drug. Such situation has heralded need for alternative therapy. Objective: This research aim was find new candidates from some Indonesia plants collected Cangar National Forest, Batu-Malang, East Java. Methods: Eleven samples leaves and stem extracts were screened against 3D7 culture maintained in...
Objective: This objective of this research was to study in vitro antimalarial activity chloroform, n-butanol, and ethyl acetate fractions ethanol extracts Carthamus tinctorius Linn. flowers from Asteraceae family which empirically been used as traditional medication by people South Sulawesi heal measles.Methods: Fractionation conducted using acetate. Determination performed test the 24-well microplate candle-jar method. Breeding is done a petri-dish aseptically. Plasmodium falciparum 3D7...
The ethanol extract of Artocarpus champeden stem bark (ACEE) has been proven to exhibit antimalarial activity. Despite the effects observed, mechanisms immune response explain activity ACEE remain poorly characterized. Here, we show production pro- and anti-inflammatory cytokines T helper 1 (Th1: IFN-γ, TNF-α) 2 (Th2: IL-10) from Plasmodium berghei-infected mice treated with formulated in order better characterize mechanism behind ACEE's In addition, have also determined effect on parasite...
Carthamus tinctorius Linn, also known as safflower, is a plant with the potential of being used in production antimalarial drugs. The purpose this study was to isolate and identify steroid compounds safflower determine its activity vitro. isolation process conducted through extraction chromatography methods. Then, characterization isolated spectroscopic techniques which include Fourier Transform Infrared Spectroscopy (FT-IR), NMR 1-D (1H 13C-NMR), 2-D (HMQC, HMBC, H-H COZY) well comparing...
The use of extract plants as a therapy method for bacterial illnesses is possible. Plants have antibacterial and antioxidant properties include various chemicals that protect the human body from infections. And coliform bacteria are major cause public health issues. This study aimed to determine potential variety an alternative agent. was carried out with utilizing disc diffusion method. ultrasonic-assisted extraction procedure n-hexane, DMSO methanol leaf stem bark plants. Zones inhibition...
Dusun Kiringan-Jetis, Bantul, merupakan desa wisata jamu gendong dengan penduduk mayoritas berprofesi sebagai pengrajin jamu. Jamu yang mereka jual secara turun-temurun terbatas dalam bentuk jadi dan setengah jadi. Perlu adanya peningkatan diversifikasi produk untuk meningkatkan nilai jualnya. Kegiatan pengabdian pada masyarakat ini bertujuan ketrampilan usaha kualitas mengembangkan akan dijual. Untuk dapat mencapai tujuan diinginkan dari kegiatan maka dilakukan upaya: (1) Edukasi...
Three new dihydrochalcones: artoserichalcone A-C (1-3), were isolated from the leaves of Artocarpus sericicarpus. The structures compounds determined based on NMR spectrum (1H, 13C, and 2D) HRESIMS spectroscopic analysis. Compounds (1) (3) showed active antimalarial activity with IC50 values 16.90 13.56 µM, respectively. Meanwhile, compound (2) an value 63.01 µM was categorised as a moderate substance. cytotoxicity against Huh7, HepG2, BHK-21, Vero cells that (1-3) CC50 > 20 µg/mL could be...
Background: Hepatitis C Virus infection is a serious health problem that leads to chronic liver disease, cirrhosis, hepatocellular carcinoma, which causes high morbidity. Direct-Acting Antiviral Agents have been used as anti-hepatitis therapy. However, it was covered only in limited patients due the cost. Moreover, side effects and resistance cases were also reported some HCV genotypes. Objective: This research aimed find new anti-HCV from Indonesia plants collected Balikpapan Botanical...
Desa Ngadisari, Kabupaten Probolinggo memiliki beragam tanaman liar yang berpotensi dimanfaatkan untuk pengobatan. Beberapa diantaranya adalah adas, jarak, kecubung, keningar, purwoceng, krangean, kayu ampet, pulosari, dan pronojiwo. Beragamnya ada di sekitar masyarakat setempat merupakan kekayaan tersendiri dari daerah ini, namun tidak banyak Ngadisari memanfaatkannya secara baik. Hal ini terjadi karena aspek kekurangpraktisan yaitu bahan-bahannya harus diramu terlebih dahulu, selain itu...