A5005210802- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Fatty Acid Research and Health
- Vaccine Coverage and Hesitancy
- Airway Management and Intubation Techniques
- Disaster Response and Management
- Healthcare professionals’ stress and burnout
- X-ray Diffraction in Crystallography
- COVID-19 and healthcare impacts
- Trace Elements in Health
- Simulation-Based Education in Healthcare
- Crystallization and Solubility Studies
- Innovations in Medical Education
- Exercise and Physiological Responses
- Oral microbiology and periodontitis research
- Biochemical effects in animals
- Cholesterol and Lipid Metabolism
- SARS-CoV-2 and COVID-19 Research
- Heavy Metal Exposure and Toxicity
- Phytoestrogen effects and research
- Nursing education and management
- Healthcare Policy and Management
- T-cell and B-cell Immunology
- Ultrasound in Clinical Applications
The Ohio State University
2021-2025
National Registry of Emergency Medical Technicians
2021-2025
The Ohio State University Wexner Medical Center
2021-2025
Medicover
2024
National Student Clearinghouse Research Center
2023
Carnegie Mellon University
2017
Austen BioInnovation Institute in Akron
2017
Thomas Jefferson University
2017
University of Pittsburgh Medical Center
2017
Renaissance Services (United States)
2017
Dietary composition has been shown to influence metabolism and impact on the prevalence risk for certain diseases, but hitherto, there have no systematic studies effects of dietary modulation human metabolic phenotype (metabotype). Here, we applied 1H NMR spectroscopy in combination with multivariate statistical analysis characterize three diets: "vegetarian", "low meat", "high meat" metabotype signature participants. Twelve healthy male participants (age range 25−74 years) consumed each...
Abstract Greatly increasing the amounts of flaxseed oil [rich in α‐linolenic acid (ALNA)] or fish (FO); eicosapentaenoic (EPA) and docosahexaenoic (DHA)] diet can decrease inflammatory cell functions so might impair host defense. The objective this study was to determine effect dietary supplementation with moderate levels ALNA, γ‐linolenic (GLA), arachidonic (ARA), DHA, FO on numbers circulating soluble adhesion molecules. Healthy subjects aged 55 75 yr consumed nine capsules per day for 12...
Limited recent national data exist measuring burnout levels among emergency medical services (EMS) clinicians and the potential impact of on workforce strength stability. We aimed to measure current EMS its association with workforce-reducing factors. In April 2022, a random sample nationally certified was sent survey that included Copenhagen Burnout Inventory (CBI) assess for in 3 dimensions: personal, work-related, patient-related. Descriptive statistics (count percentage) multivariable...
Abstract Numerous indicators for disease progression have been described in the last decade. The purpose of this study was to examine, longitudinally, a large battery clinical, microbiological, and immunological indicators, try determine whether presence one or combination these parameters at baseline, would correlate positively with increased attachment bone loss (true prognostic factors). Following initial screening, 79 patients established periodontitis were monitored longitudinally year....
The biochemical effects of acute and chronic psychological stress have been investigated in male Sprague−Dawley rats using a combination 1H NMR spectral analysis plasma conventional hematological analyses. Animals were subjected to 35 consecutive days 6-h sessions stress, following 9 day break, stressed for further period. Plasma samples collected at 0, 1, 3, 6 h on 9, 21, 35, 44, measured 600 MHz spectroscopy, analyzed by Principal Components Analysis. Time-dependent range endogenous...
OBJECTIVES Detailed job satisfaction evaluations are often used to build strategies for employee retention. Despite recognizing that emergency medical services (EMS) dissatisfaction drives turnover, validated tools rigorously evaluating have not been employed. We aim assess the association between EMS clinician and their likelihood of leaving profession using Spector Job Satisfaction Survey (JSS).
Soluble forms of intercellular adhesion molecule-1, vascular cell molecule-1 and E-selectin (termed sICAM-1, sVCAM-1 sE-selectin respectively) are found in the plasma, elevated during inflammatory conditions which there is increased expression cellular molecules on endothelial other cells. concentrations were measured plasma 140 healthy Caucasian subjects aged between 18 75 years (100 males/40 females). sICAM-1 varied 59.9 299.7 ng/ml (median 150 ng/ml), 222.8 1672.9 662 ng/ml) 12.4 90.3...
The aim of the present study was to investigate whether 2 weeks vitamin C supplementation affects recovery from an unaccustomed bout exercise. Sixteen male subjects were allocated either a placebo (P; n = 8) or group (VC; 8). VC consumed 200 mg ascorbic acid twice day, whereas P identical capsules containing lactose. Subjects performed prolonged (90-min) intermittent shuttle-running test 14 days after began. Post-exercise serum creatine kinase activities and myoglobin concentrations...
Abstract We have estimated the levels of Interleukin‐1 beta (IL‐1β) by ELISA in gingival crevicular fluid (GCF) at 58 sites from 37 patients with adult periodontitis. GCF was collected for 5 s on filter papers and a 2nd sample 30 1 min later. 68/116 strips yielded detectable IL‐1β. IL‐1β present both st samples 28 sites, only 4 8 sites; 18 were below level detection assay. When concentrations calculated original volume each strip, mean value positive 34.16±29.45 (SD) pg/μ1 range 1.75 to...
Amyloids are aggregated proteins characterized by a specific cross-β-sheet structure and typically associated with neurodegenerative diseases including Alzheimer's disease. Recently, however, several nonpathological amyloids have been found in intracellular organelles of normal mammalian tissues suggesting that amyloid may also carry out biological functions. We previously shown the epididymal cystatin CRES (cystatin-related spermatogenic), cst8, reproductive-specific member superfamily...
Abstract Objective There is growing concern with the strength and stability of emergency medical services (EMS) workforce reports challenges in many communities United States. Our objective was to estimate changes EMS by evaluating number clinicians who enter, stay, leave. Methods A 4‐year retrospective cohort evaluation all certified at technician (EMT) level or higher conducted for 9 states that require national certification obtain maintain licensure. The study spanned 2 recertification...
Objective: Vitamin E and C given separately improve insulin sensitivity due to an inhibitory effect on oxidative stress inflammation, however their combined glucose control inflammation is unknown. To investigate of in elderly with Impaired Fasting Glucose (IFG) action substrate oxidation.Design: Controlled-trial administration (1000 mg/day) UI/day) for four weeks. Hyperinsulinemic euglycemic clamp was performed before following supplementation.Setting: Out-patient clinic.Participants:...
The aim of the study was to determine effect consuming meals with different fatty acid compositions on postprandial changes over 6 h in plasma triacylglycerol, NEFA, total cholesterol, glucose and insulin concentrations middle-aged men women. Men (n 11; 58 (5) years) women 56 (4) consumed four test a similar macronutrient energy content random order: reference meal based habitual pattern intake UK, an increased (155 %) linoleic (LA) alpha-linolenic (alphaLNA) ratio (high LA:alphaLNA), (23...
Up to 80 % of the Western female population experience premenstrual syndrome (PMS). Long-term pharmacological therapy is unacceptable most women, and not warranted for moderate symptoms. Nutritional therapies are popular, but lack a clear evidence base. Anecdotal suggests beneficial effects soy isoflavones because their influence on endogenous oestrogen actions specific tissues. The effect isolated soya protein (ISP) containing 68 mg/d (aglycone equivalents) (IF) symptom severity was studied...
Genetic and biochemical studies have indicated an important role for lipid metabolism in human longevity. Ashkenazi Jewish centenarians their offspring large low-density lipoprotein (LDL) high-density (HDL) particles as compared with control individuals. This profile also coincided a lower prevalence of disease. Here, we investigate whether this observation can be confirmed familial longevity outbred European population it extended to sporadic the general population.NMR-measured profiles...
This project sought to develop evidence-based guidelines for the administration of analgesics moderate severe pain by Emergency Medical Services (EMS) clinicians based on a separate, previously published, systematic review comparative effectiveness in prehospital setting prepared University Connecticut Evidence-Based Practice Center Agency Healthcare Research and Quality (AHRQ). A technical expert panel (TEP) was assembled consisting subject matter experts emergency care, development patient...