- Diabetic Foot Ulcer Assessment and Management
- Chronic Kidney Disease and Diabetes
- Metabolism, Diabetes, and Cancer
- Diabetes Treatment and Management
- Diabetes Management and Research
- Electrolyte and hormonal disorders
- Urinary Bladder and Prostate Research
- Pancreatic function and diabetes
- Protein Tyrosine Phosphatases
- Sinusitis and nasal conditions
- Diabetes and associated disorders
- Peripheral Artery Disease Management
- Pituitary Gland Disorders and Treatments
- Wound Healing and Treatments
- Pelvic floor disorders treatments
- Advanced Statistical Process Monitoring
- Sexual function and dysfunction studies
- Neuroendocrine Tumor Research Advances
- Pharmacy and Medical Practices
- Skin Diseases and Diabetes
- Nasal Surgery and Airway Studies
- Biochemical Acid Research Studies
- Sympathectomy and Hyperhidrosis Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Therapeutic Uses of Natural Elements
Saiseikai Central Hospital
2008-2017
Jikei University School of Medicine
2005
The associations of insulin resistance and glycemic control with the risk kidney stones were explored.Generally healthy Japanese (n=2,171) who visited Saiseikai Central Hospital (Tokyo, Japan) for a health check included in cross-sectional study. We calculated odds ratios (OR) having terms four measures: fasting serum insulin, homeostasis model assessment (HOMA-IR), plasma glucose (FPG) glycosylated hemoglobin (HbA1c), adjusting possible factors stones.Fasting HOMA-IR non-significantly...
Aim. To determine the diabetic foot ulcer incidence and examine its association with microangiopathy complications, including retinopathy (DR) albuminuria (Alb), in type 2 diabetes patients. Methods. This was a retrospective cohort study of 1,305 patients who were assigned to following groups: Category 1, normoalbuminuria without DR (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle="italic">712</mml:mn></mml:math>); 2, Alb...
Introduction . It was reported that 25-hydroxyvitamin D level independently associated with anemia in chronic kidney diseases, but the relation between vitamin and diabetes mellitus is not still certain. We analyzed plasma hemoglobin concentration. Materials Methods A cross-sectional study male patients type 2 performed. Correlation coefficients standardized partial regression coefficient for concentration were evaluated. Results Hemoglobin positively correlated body mass index, HbA1c,...
This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination defecation. The Rome III criteria evaluation of defecation, Overactive Bladder Symptom Score (OABSS) symptoms, clinical features were investigated 145 patients. Latent FC moderate severe overactive bladder (OAB) defined on basis positivity two or more an OABSS ≥ 6 Q3 2, respectively. In 60 latent patients, was...
Objective The significance of estimated glomerular filtration rate (e-GFR) in diabetic nephropathy has yet to be clearly determined. We therefore compared albuminuria and e-GFR for usefulness predicting progressive decline renal function. Methods A total 1,303 subjects with type 2 diabetes mellitus whose was more than 30 mL/min/1.73 m2 were followed three years. Associations clinical staging based on AER that progression insufficiency (e-GFR <30 m2) evaluated. Results On univariate analysis,...
Introduction. There is no report about risk factors for renal deterioration according to the clinical stage, divided by estimated glomerular filtration rate (eGFR) in type 2 diabetes. Materials and Methods. We evaluated correlated with annual eGFR decline 1303 subjects diabetes whose was ≥30 mL/min/1.73 m(2). strata were defined baseline value as follows: stratum 1: ≥90, 2: ≥60, <90, 3: ≥30, <60. Results. The 2.3 ± 5.4 m(2) overall subjects. Multiple linear regression analysis demonstrated...
Introduction. Relation between atherosclerosis and innate immunity has attracted attention. As the antimicrobial peptide, LL-37, could have an important role in atherosclerosis, we supposed that there be a meaningful association of plasma LL-37 level with risk factors for cardiovascular disease subjects type 2 diabetes mellitus. Materials Methods. We evaluated other clinical markers Japanese mellitus (n = 133, 115 men 18 women; age 64.7 ± 11.5 years; HbA1c 8.1 1.6%). Plasma was measured by...
We hypothesized that higher body mass index (BMI) was associated with increased prevalence of paranasal sinus disease and examined the hypothesis in Japanese adults.This a cross-sectional study including 1350 adults aged 40 years or more who participated health check-up program focusing on brain diseases metabolic syndrome. Participants were divided into quartiles BMI levels. Paranasal confirmed by head MRI scan. The association between using logistic regression analysis, which adjusted for...
Aims . We analyzed the prevalence of nephropathy according to past body weight status in Japanese subjects with type 2 diabetes because influence obesity on diabetic complications is not certain. Methods examined 2927 mellitus current BMI and maximum past. defined “current obesity” as hospitalization 25 or more, “previous less than self-reported “continuously lean” 25. Results The was significantly higher (40.6%) previous (35.6%) those who were continuously lean (24.3%) (<mml:math...
Background: The dose-response relationship between glycemic status and lung function has not been thoroughly investigated. We hypothesized that there are continuous inverse associations measures tests examined the hypothesis in Japanese adults.Methods: cross-sectionally investigated of hemoglobin A1c (HbA1c) fasting plasma glucose (FPG) with forced vital capacity (FVC) expiratory volume one second (FEV1) 3161 adults who participated a health screening from 2008 to 2011. study participants...
Diabet. Med. 29, e138–e141 (2012) Abstract Background Insulinoma is a tumour of insulin‐producing cells the pancreas and known to be one causes hypoglycaemia. Usually, appropriate removal insulinoma results in normalization blood glucose levels. However, we found novel cases insulinoma, which hyperglycaemia developed soon after resection insulinoma. Case report We encountered two patients with repeated hypoglycaemia caused by Following unanticipated was observed both patients. Thereafter,...
Background: The association between diabetes and paranasal sinus disease has not been thoroughly investigated.Methods: We cross-sectionally investigated the presence of disease, which was confirmed by a head MRI scan in 1350 adults who underwent health screening program focusing on brain diseases metabolic syndrome. Logistic regression, adjusted for age, sex, body mass index, waist-to-hip ratio, hypertension, smoking status, alcohol intake, white blood cell count, performed to calculate odds...
The detection rate and associated factors of at least one sperm in urinary sediment is not well-known real clinical practice.The aim the present study was to evaluate features with presence a large number samples.We conducted cross-sectional Tokyo Saiseikai Central Hospital. We identified 5,005 males who were aged ≥20 years whom sedimentation had been performed twice between May 2011 June 2012. group included patients test under microscope detected sperm. evaluated associations parameters...
Objective The effect of pioglitazone on high-density lipoprotein cholesterol (HDL-C) has been attracting attention. However, there are limited data the characteristics patients who likely to respond in terms improvement HDL-C levels (lipid responders). In present study, lipid responders were investigated. Methods Five hundred and sixty-three with type 2 diabetes started treatment followed for six months. They divided into two groups according response pioglitazone. Subjects whose increased...