Khaled Youssef

ORCID: 0000-0003-3448-4384
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About
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Research Areas
  • Genetics, Aging, and Longevity in Model Organisms
  • Photoreceptor and optogenetics research
  • Neuroscience and Neural Engineering
  • Microfluidic and Capillary Electrophoresis Applications
  • Advanced Fluorescence Microscopy Techniques
  • Wind Energy Research and Development
  • Biosensors and Analytical Detection
  • Advanced Sensor and Energy Harvesting Materials
  • Zebrafish Biomedical Research Applications
  • Microfluidic and Bio-sensing Technologies
  • Analytical chemistry methods development
  • Circadian rhythm and melatonin
  • Fish biology, ecology, and behavior
  • Fluid Dynamics and Vibration Analysis
  • Microplastics and Plastic Pollution
  • Fish Ecology and Management Studies
  • Wind and Air Flow Studies
  • 3D Printing in Biomedical Research
  • Planarian Biology and Electrostimulation
  • Innovative Energy Harvesting Technologies
  • Plant and Biological Electrophysiology Studies
  • Plant Physiology and Cultivation Studies
  • Listeria monocytogenes in Food Safety
  • Spaceflight effects on biology
  • Tea Polyphenols and Effects

Ain Shams University
2015-2024

York University
2017-2023

Toronto Public Health
2021

Portulaca oleracea is globally used both as a vegetable and an herb for medical therapeutic purposes; hence the need to investigate its phytonutrients. The aim of this study was evaluate effects different drying methods (hot-air drying, microwave freeze-drying) on color, phytochemicals content antioxidant capacity purslane leaves. fresh leaves had high contents total phenolics (1447.59 mg GAE/ 100 g) flavonoids (5011.87 QE/ dry weight basis. They exhibited (53.23% 147.78 μmol trolox/...

10.4172/2155-9600.1000322 article EN Journal of Nutrition & Food Sciences 2014-01-01

Ocean waves are one of the cleanest and most abundant energy sources on earth, wave has potential for future power generation. Triboelectric nanogenerator (TENG) technology recently been proposed as a promising to harvest energy. In this paper, theoretical study is performed duck-shaped TENG harvester introduced in our work. To enhance design harvester, mechanical electrical characteristics harvester's overall structure, well its inner configuration, analyzed, respectively, under different...

10.1088/1361-6528/aa6612 article EN Nanotechnology 2017-04-11

Molecularly imprinted polymers (MIPs) and cell-imprinter (CIPs) have emerged as synthetic recognition elements in biomimetic sensors. In this paper, we conducted a parametric study to optimize bulk polymerization methodology for uniform functionalization of stainless steel microwires (MWs) with CIPs comprising single fourplex combinations functional monomers (FMs). MWs are widely used biosensors, their single-FM MIPs has been demonstrated. Complex multiple FMs shown enhanced selectivity...

10.1021/acsapm.2c01886 article EN ACS Applied Polymer Materials 2023-01-23

This work presents an innovative technique to enhance the performance of Savonius wind turbine. The new is based on introducing upstream deflector and downstream baffle. shape location both devices are optimized using a genetic algorithm. turbine with compared single performance. study employs finite volume solver (ANSYS-FLUENT) solve unsteady Reynolds Averaged Navier–Stokes equations turbulence model equations. configuration results in much higher power coefficient than average peak baffle...

10.1177/0309524x19849860 article EN Wind Engineering 2019-05-29

Abstract Behavioral responses of zebrafish larvae to environmental cues are important functional readouts that should be evoked on-demand and studied phenotypically in behavioral, genetical developmental investigations. Very recently, it was shown execute a voluntary oriented movement toward the positive electrode an electric field along microchannel. Phenotypic characterization this response not feasible due larva’s rapid channel. To overcome challenge, microfluidic device introduced...

10.1093/intbio/zyz031 article EN Integrative Biology 2019-10-01

In this paper, we report a novel microfluidic method to conduct Caenorhabditis elegans electrotaxis movement assay and neuronal imaging on up 16 worms in parallel. C. is model organism for neurodegenerative disease disorders such as Parkinson's (PD), screening chemicals that alleviate protein aggregation, death, impairment PD. Electrotaxis of channels has led the development neurobehavioral platforms, but enhancing throughput electrotactic behavioral remained challenge. Our device consisted...

10.3390/mi11080756 article EN cc-by Micromachines 2020-08-04

Microfluidic devices are being used for phenotypic screening of zebrafish larvae in fundamental and pre-clinical research. A challenge the broad use these microfluidic is their low throughput, especially behavioral assays. Previously, we introduced tail locomotion a semi-mobile larva evoked on-demand with electric signal device. Here, report lessons learned increasing number specimens from one to four this device.Multiple parameters including loading testing time per fish orientation...

10.1002/biot.202100076 article EN Biotechnology Journal 2021-09-04

The present work investigates the performance of Savonius wind turbine using two or three rotors. new design was found to have higher power coefficient compared with single rotor design. peak average rotors computed be 50% than that torque also at high tip speed ratio. This improved is attributed favorable aerodynamic interaction between which accelerates flow around and generates turning in direction rotation for each rotor. optimized arrangement showed upstream one downstream should a...

10.1115/gt2015-43988 article EN Volume 9: Oil and Gas Applications; Supercritical CO2 Power Cycles; Wind Energy 2015-06-15

In this paper, the novel effect of electric field (EF) on adult C. elegans egg-laying in a microchannel is discovered and correlated with neural muscular activities. The quantitative effects worm aging EF strength, direction, exposure duration are studied phenotypically using egg-count, body length, head movement, transient neuronal activity readouts. Electric rate increases significantly when worms face anode response EF-dependent, i.e. stronger (6 V cm-1) longer (40 s) result shorter egg...

10.1039/d0lc00964d article EN Lab on a Chip 2021-01-01

Rheological properties, peroxide value, and FTIR spectra of olive, chia, garden cress oils exposed to high temperatures (150, 175, 200 ºC) for different times (30, 60, 120 minutes) were assayed. The shear stress versus rate data (at 25 was fitted Newtonian, Bingham, power law rheological mathematical models. Fresh tested showed Newtonian flow behavior with correlation coefficients higher than 0.99 slight non-Newtonian after heat treatment at times. values the significantly increased...

10.48185/jcnb.v5i2.1228 article EN Journal of Chemistry and Nutritional Biochemistry 2024-07-16

Abstract Background Achalasia is characterized by the absence of peristaltic movement in lower esophageal sphincter, resulting impaired relaxation during food ingestion. The incidence achalasia similar between men and women, affecting approximately 1 100,000 individuals annually, with a prevalence 10 people. It most commonly diagnosed ages 30 60 years. High-resolution manometry considered gold standard for diagnosis, revealing body aperistalsis hypertensive sphincter. While laparoscopic...

10.1093/qjmed/hcae175.473 article EN QJM 2024-10-01

Caenorhabditis elegans ( C. ) is an optically transparent nematode that shares many gene orthologs and homologs with humans. are widely used in large populations for genetic studies relevant to human biology disease. Success of such frequently relies on the ability image structure at high-resolution high-speed. In this manuscript, we report feasibility suitability a high-speed variant reflectance confocal microscopy, known as spectrally encoded microscopy (SECM), label-free imaging elegans....

10.1364/boe.427685 article EN cc-by Biomedical Optics Express 2021-05-18

Selective plane illumination microscopy (SPIM) is an emerging fluorescent imaging technique suitable for noninvasive volumetric of C. elegans. These promising systems, however, are scarce in academic and research institutions due to their high cost technical complexities. Simple low-cost solutions that enable conversion commonplace wide-field microscopes rapid SPIM platforms promote widespread adoption by biologist studying neuronal expressions elegans.We sought develop a simple optofluidic...

10.1117/1.jbo.26.12.126501 article EN cc-by Journal of Biomedical Optics 2021-12-10

ABSTRACT In this paper, the novel effect of electric field (EF) on adult C. elegans egg-laying in a microchannel is discovered and correlated with neural muscular activities. The quantitative effects worm aging EF strength, direction, exposure duration studied phenotypically using egg-count, body length, head movement, transient neuronal activity readouts. Electric rate increases significantly when worms face anode response EF-dependent, i.e. stronger (6V/cm) longer (40s) result shorter egg...

10.1101/2020.09.01.276097 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-09-01

This work reports on the development of a low-cost and compact optofluidic add-on device for converting conventional wide-field microscope to light sheet fluorescence immobilization-free imaging C. elegans model organism. The developed Polydimethylsiloxane (PDMS)-based consists an integrated PDMS cylindrical lens light-sheet generation microfluidics channel flow-based translation samples through sheet. Validation experiments several strains demonstrate ability in volumetric expressions...

10.1117/12.2607134 article EN 2022-03-04

Molecular imprinting has advanced towards synthesizing whole-cell imprints of microorganisms such as bacteria on various sensor surfaces including wire electrodes, quartz crystal microbalances, and microparticles (MPs). We recently introduced cell-imprinted polymers (CIPs) coated MPs, called CIP-MPs, for recovery from water. In this paper, we have real-time fluorometric E. coli detection by applying the fluorescent magnetic which were captured soft ferromagnetic microstructures integrated...

10.2139/ssrn.4536613 preprint EN 2023-01-01
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