A5062242131- Molecular Sensors and Ion Detection
- Metal complexes synthesis and properties
- Electrochemical Analysis and Applications
- Analytical Chemistry and Chromatography
- Synthesis and Characterization of Heterocyclic Compounds
- Protein Interaction Studies and Fluorescence Analysis
- Luminescence and Fluorescent Materials
- Chemical and Physical Properties in Aqueous Solutions
- Inorganic and Organometallic Chemistry
- Free Radicals and Antioxidants
- Analytical Chemistry and Sensors
- Chemical Reaction Mechanisms
- Computational Drug Discovery Methods
- Advanced biosensing and bioanalysis techniques
- Chemical Thermodynamics and Molecular Structure
- Synthesis and biological activity
- Lanthanide and Transition Metal Complexes
- Molecular spectroscopy and chirality
- Electrochemical sensors and biosensors
- Crystallization and Solubility Studies
- Sulfur Compounds in Biology
- Surfactants and Colloidal Systems
- Lipid Membrane Structure and Behavior
- Protein purification and stability
- Crystal structures of chemical compounds
Ivanovo State University of Chemistry and Technology
2013-2024
This article discusses the design and analysis of a new chemical chemosensor for detecting mercury(II) ions. The is hydrazone made from 4-methylthiazole-5-carbaldehyde fluorescein hydrazide. structure was confirmed using various methods, including nuclear magnetic resonance spectroscopy, infrared spectroscopy with Fourier transformation, mass quantum calculations. sensor's ability in highly selective sensitive discovery Hg2+ ions water demonstrated. detection limit determined to be 0.23 µM....
This review presents an analysis of different algorithms for predicting the sensory ability organic compounds towards metal ions based on their chemical formula. A database chemosensors containing information various classes suitable compounds, including dipyrromethenes, BODIPY, Schiff bases, hydrazones, fluorescein, rhodamine, phenanthroline, coumarin, naphthalimide derivatives, and others (a total 965 molecules) has been compiled. Additionally, a freely available software developed sensing...
Present paper reports on the interactions between four hydrazones derived from pyridoxal and hydrazides of 2-furoic, thiophene-2-carboxylic, pyrazinoic pyridine-3-carboxylic acids 10 different anions (F−, Cl−, I−, PO43-, HPO42-, H2PO43-, NO3−, SO32-, SO42-, CH3COO−) three cations (Co2+, Ni2+, Zn2+). Hydrazones are sensitive towards anion presence in non-buffered DMSO only, thus, indicating that proton transfer ligand is responsible for changes colour, UV-Vis fluorescent spectra. Buffered...
Pyridoxal and pyridoxal 5′-phosphate are aldehyde forms of B6 vitamin that can easily be transformed into each other in the living organism. The presence a phosphate group, however, provides related compounds (e.g., hydrazones) with better solubility water. In addition, group may sometimes act as binding center for metal ions. particular, strong ligand gold(III) ion, which is interest researchers anti-tumor antimicrobial potential gold(III). This paper aims to answer whether involved complex...
Abstract The binding of low molecular weight compounds with the transport proteins blood is an essential step their delivery into living cells and thus accurate investigation interactions occurring in solution at physiological conditions crucial for development efficient biologically active molecules. In this work, we report on complex species, stability constants thermodynamic parameters reactions hydrazones derived from pyridoxal-5ʹ-phosphate (PLP) bovine human serum albumin (BSA HSA)...
Abstract A new hydrazone based on 5‐nitrofurfural and 2‐hydrazinobenzothiazole ( L ) was introduced as a colorimetric chemosensor for rapid, selective, sensitive detection of CN − ions in aqueous media. The characterized using spectral methods such FT‐IR, 1 H, 13 C NMR, UV‐Vis, mass spectrometry. interaction with the ion provides marked color change from yellow to blue‐green or blue, depending concentration cyanide ions. colour well absorption maxima make it possible detect naked eye. limit...
Ascorbic acid is one of the essential compounds for living organisms. The reductive properties ascorbate depend significantly on dissociation ascorbic acid, which, in turn, influenced by ionic strength value. protonation dianion was studied an aqueous solution at T = 298.2 K; p 0.1 MPa; and I 0.10, 0.25, 0.5, 1.0, 2.0, 3.0, 5.0 mol L–1 (NaCl) using spectropotentiometric technique. Protonation constants were calculated from spectral data. analysis influence performed modified Davies equation...
Today, complexes of gold(I) and gold(III) are recognized as promising drugs for the treatment bacterial infectious diseases oncological diseases, respectively. It is interest to broaden area potential use compounds pathogenic microorganism well. The first step towards development new antibacterial based on Au3+ study their stability in an aqueous solution. present contribution reports investigation complexation with five hydrazones derived from a well-known biologically active compound,...
The paper summarizes the results of our own research into formation molecular complexes cyclodextrins with biologically active polyphenol compounds in water-organic solvents, chemical equilibria solutions hydrazones and Schiff bases their metal DNA proteins. It was found that an increase content non-aqueous component binary solvent leads to a decrease stability polyphenols exothermicity reactions. has been shown aqueous buffer solution containing also or protein dissociate, released cation...
The present work reports on stoichiometry, apparent stability constants of biologically relevant complexes nickel(II), cobalt(III) with hydrazones derived from pyridoxal 5′-phosphate and hydrazides 2-,3-,4-pyridinecarboxylic acids at pH 7.4, T = 25.0 °C, I 0.25 determined using UV-Vis spectroscopy. thermodynamic some formation (NiL, NiL2, NiL2H) were estimated. Cobalt(II) ion was found to be oxidized cobalt(III). Co(II) Co(III) form low-spin state complexes. Hydrazones binding ability...
Lanthanides such as cerium(III), europium(III), and gadolinium(III) are widely used for designing fluorescent probes or magnetic resonance imaging contrasting agents biological systems. The synthesis study of lanthanide complexes in buffer solutions imitating fluids often complicated because a lack data on the interactions with solution components. Therefore, Ln(III) [where = La(III), Ce(III), Gd(III), Eu(III)] complexation agent, tris(hydroxymethyl)aminomethane (Tris), aqueous is studied...