A5040548612- Animal Nutrition and Physiology
- Obesity, Physical Activity, Diet
- Cancer therapeutics and mechanisms
- Nutrition and Health in Aging
- Cell death mechanisms and regulation
- Microtubule and mitosis dynamics
- Ginkgo biloba and Cashew Applications
- Child Nutrition and Water Access
- Phenothiazines and Benzothiazines Synthesis and Activities
- Childhood Cancer Survivors' Quality of Life
- Trace Elements in Health
- Livestock and Poultry Management
- Effects and risks of endocrine disrupting chemicals
- Rabbits: Nutrition, Reproduction, Health
- Synthesis and biological activity
- Enzyme function and inhibition
- Phytoestrogen effects and research
- Hypothalamic control of reproductive hormones
- Moringa oleifera research and applications
- Advanced Glycation End Products research
- RNA Interference and Gene Delivery
- Methane Hydrates and Related Phenomena
- Tea Polyphenols and Effects
- 14-3-3 protein interactions
- Selenium in Biological Systems
University of Veterinary and Animal Sciences
2017-2025
University of Karachi
2025
International Center for Chemical and Biological Sciences
2025
AtlantiCare
2025
Regional Medical Center
2025
Khan Academy
2023
Rasool Akram Hospital
2023
AbbVie (United States)
2015
Abbott (United States)
2000-2007
Abbott Fund
2000-2001
Abstract The anti-apoptotic protein MCL-1 is a key regulator of cancer cell survival and known resistance factor for small-molecule BCL-2 family inhibitors such as ABT-263 (navitoclax), making it an attractive therapeutic target. However, directly inhibiting this target requires the disruption high-affinity protein–protein interactions, therefore designing small molecules potent enough to inhibit in cells has proven extremely challenging. Here, we describe series indole-2-carboxylic acids,...
A recurring problem with cancer therapies is the development of drug resistance. While investigating protein profile cells resistant to a novel antimitotic compound (A204197), we discovered an increase in annexin IV expression. When examined expression level paclitaxel-resistant cell line (H460/T800), found that was also overexpressed. Interestingly closely related protein, II, not overexpressed H460/T800 cells. Immunostaining either II or antibody revealed primarily located nucleus...
This study examines the financial performance of diversified portfolios composed various asset categories, including green cryptocurrencies, non-green energy stocks leading companies, top and prominent sustainable companies within context G7 nations. Additionally, it investigates cryptocurrency across these regions. It aims to compare returns while examining initiatives undertaken by countries foster systems. The research also explores how investors can leverage portfolio optimization...
The current study aimed to evaluate the efficacy of selenium nanoparticles (SeNPs), combined or loaded with chitosan (COS), in broiler chickens reared under standard management protocols. parameters investigation were production performance, organ development, components intestinal barrier, and ileal microbial count. Two hundred forty day-old chicks raised five groups, each group containing eight replicates (n=6/replicate). control received a basal diet whereas other four groups diets...
The present study was designed to investigate the effects of co-supplementation β-galacto-oligosaccharides (β-GOS), a prebiotic, and methionine on selected meat quality traits, pathways governing breast muscle formation degradation in broilers.Day-old broilers (n = 288) were distributed 3×2 factorial design (6 groups 6 replicates/group) based three dietary levels β-GOS (0, 0.2 0.5%) two (0.5 1.0%).On day 35, birds per replicate (12 group) exsanguinated collect samples for analysis.Results...
The current research aimed to evaluate the supplemental effects of iron oxide nanoparticles (IONPs) on production performance, viscera development, blood metabolites, redox status, meat quality, and jejunal histology in broilers. A total 300 day-old broilers were randomly divided into six groups with five replicates per group. Birds fed a corn soybean-based diet supplemented 0, 20, 40, 60, or 80 mg/kg IONPs FeSO4 for 35 days. feed conversion ratio (FCR) was improved birds 60 IONPs. pH24h...
The goal of the present research was to evaluate effects chromium-loaded chitosan nanoparticles (Cr-CNPs) on production performance, viscera development, serum metabolites and intestinal histology in broilers. Two hundred (200) day-old broilers were randomly divided into five groups with replicates (n = 8). Birds first group served as control fed a corn soybean-based diet, while remaining four supplemented offered 200, 400, 800, 1200 μg Cr-CNPs/kg feed, respectively, for 35 days. Weight...
Malnutrition is common in liver cirrhosis patients that correlated with early complications, morbidity and mortality.The purpose of the study was to assess nutritional status, impact screening intervention by evaluating their actual energy protein intake during hospital stay.A cross sectional conducted wherein all patients' status defined Subjective Global Assessment tool. Adequate supply were planned executed using individualized plan for dietitian's collaboration. Anthropometric...
Prebiotics supplementation modulates pre-weaning stress in male cattle calves by improving growth performance, health scores and serum biomarkers | Mohsin Raza, Muhammad Shahbaz Yousaf, Jamal Ahmad, Afzal Rashid, Khalid Abdul Majeed, Sajid Khan Tahir, Shumaila Ashraf, Numan, Abia Khalid, Habib ur Rehman Agricultural Journals
The present study aimed to evaluate the effect of chromium-loaded chitosan nanoparticles (Cr-CNPs) on electrophysiological indices, gene expression glucose transporters, and tissue glycogen in broilers. A total 200 one-day-old broilers were randomly divided into five groups, with each having replicates (n = 8). Group was fed a corn–soybean meal diet, while diets groups B, C, D, E supplemented 200, 400, 800, 1200 µg/kg Cr as Cr-CNPs, respectively. On day 35, jejunum collected for study,...