- Nuclear Structure and Function
- RNA Research and Splicing
- Genomics and Chromatin Dynamics
- Lignin and Wood Chemistry
- Geological Studies and Exploration
- Thermochemical Biomass Conversion Processes
- Coal Combustion and Slurry Processing
- Biofuel production and bioconversion
- Genetic and Kidney Cyst Diseases
- Transgenic Plants and Applications
- Aquatic and Environmental Studies
- Agricultural Development and Policies
- Lubricants and Their Additives
- Endometriosis Research and Treatment
- Advanced Cellulose Research Studies
- RNA Interference and Gene Delivery
- Technical Engine Diagnostics and Monitoring
- Engineering and Environmental Studies
- Advanced Energy Technologies and Civil Engineering Innovations
- Telomeres, Telomerase, and Senescence
- Engine and Fuel Emissions
- Engineering Diagnostics and Reliability
- Trypanosoma species research and implications
- Smart Materials for Construction
- Cellular Mechanics and Interactions
University of Dundee
2021-2023
Kazan State Technological University
2015-2022
State University of Land Use Planning
2021
Wellcome Centre for Cell Biology
2015-2017
University of Edinburgh
2014-2017
Kazan Federal University
2015-2017
Lomonosov Moscow State University
1998-2016
Pyatigorsk State Scientific Research Institute of Balneology
1992
Institute of Petroleum Chemistry
1991
Russian Academy of Sciences
1984
How eukaryotic chromosomes are compacted during mitosis has been a leading question in cell biology since the nineteenth century. Non-histone proteins such as condensin complexes contribute to chromosome shaping, but appear not be necessary for mitotic chromatin compaction. Histone modifications known affect structure. As histones undergo major changes their post-translational entry, we speculated that spectrum of cell-cycle-specific histone might compaction mitosis. To test this hypothesis,...
The surface proteins of parasitic protozoa mediate functions essential to survival within a host, including nutrient accumulation, environmental sensing and immune evasion. Several receptors involved in uptake defence from the innate response have been described African trypanosomes and, together with antigenic variation, contribute towards persistence vertebrate hosts. Significantly, superfamily invariant glycoproteins (ISGs) populates trypanosome surface, one which, ISG75, is implicated...
Changes in the peripheral distribution and amount of condensed chromatin are observed a number diseases linked to mutations lamin A protein nuclear envelope. We postulated that interactions with envelope transmembrane proteins (NETs) affect structure might be altered these so screened thirty-one NETs for those promote compaction as determined by an increase clusters high pixel intensity. One these, NET23 (also called STING, MITA, MPYS, ERIS, Tmem173), strongly promoted compaction....
Significance During cell division, microtubules apply piconewton forces to segregate duplicated chromosomes into daughter cells. The kinetochore, located on the surface of centromere chromatin, couples chromosomes. Little is known about folding centromeric chromatin and how this templates functional ultrastructure kinetochore. To better understand fundamental problem, we used a microscopy technique that allowed DNA associated with be unfolded accurately measured in presence absence several...
Eukaryotic cells arose ~1.5 billion years ago, with the endomembrane system a central feature, facilitating evolution of intracellular compartments. Endomembranes include nuclear envelope (NE) dividing cytoplasm and nucleoplasm. The NE possesses universal features: double lipid bilayer membrane, pore complexes (NPCs), continuity endoplasmic reticulum, indicating common evolutionary origin. However, levels specialization between lineages remains unclear, despite distinct mechanisms...
Lamins form a scaffold lining the nucleus that binds chromatin and contributes to spatial genome organization; however, due many other functions of lamins, studies knocking out or altering lamin polymer cannot clearly distinguish between direct indirect effects. To overcome this obstacle, we specifically targeted mapped histone-binding site A/C lamins by microinjecting antibodies specific region predicting would make more mobile. No increase in mobility was observed; interestingly, injected...
Abstract: It is a common misconception to view the "cyto"-skeleton as just filament systems in "cyto"-plasm. In fact, cytoskeleton extends into nucleus where complex network connects chromatin, and it also through plasma membrane of adjacent cells "exo"-skeleton extracellular matrix. This review will focus principally on subcomplex associated with nucleus, often referred nucleoskeleton, but context its extensive interconnectivity rest cytoplasmic all way exoskeleton. The made type-V...
During research were investigated various geochemical indices of snow cover state in the area Russia midland: gross mass dust sample, total load contamination for each studied toxicant, concentration ratio chemical elements dust, captured by cover, and coefficient relative gain load. There was established that quantitative composition snow’s solid residue testified about substantial influence iron steel enterprise, as well other sources contamination, situated at adjacent territory, on...
The estimation of prevalence iodine-deficiency condition among children and teenagers in two ecologically different areas the city Bratsk is given. On basis given results practical recommendations aimed at eliminating iodine deficiency conditions present anthropogenic load are proposed.
Research of the thermal decomposition Tetra Pak had been done. Thermal analysis Pak, cardboard and polyethylene TG data showed that occurred in three stages: drying melting at first stage, second stage happened; third took place. Fast pyrolysis laboratory scale setup Experiments on done temperatures 250, 450 650 °C. During fast we can have 30 % liquid products 45 solid which be used different applications. Gas chromatography-mass spectrometry samples