Roman Rohrbach
- CAR-T cell therapy research
- COVID-19 diagnosis using AI
- Cancer Immunotherapy and Biomarkers
- Respiratory viral infections research
- Biomedical Ethics and Regulation
- Otolaryngology and Infectious Diseases
- Oral Health Pathology and Treatment
- Gut microbiota and health
- Dermatological and COVID-19 studies
German Cancer Research Center
2020-2023
Heidelberg University
2020-2023
DKFZ-ZMBH Alliance
2021
Abstract Background At the entry site of respiratory virus infections, oropharyngeal microbiome has been proposed as a major hub integrating viral and host immune signals. Early studies suggested that infections with severe acute syndrome coronavirus 2 (SARS-CoV-2) are associated changes upper lower airway microbiome, specific microbial signatures may predict disease 2019 (COVID-19) illness. However, results not conclusive, critical illness can drastically alter patient’s through multiple...
Abstract Coronavirus 2 (SARS-CoV-2) infection and the resulting COVID-19 illness vary from asymptomatic disease, mild upper respiratory tract infection, pneumonia 1 , to a life-threatening multi-organ failure with case fatality rates ranging 0.27–13.4% 2,3 . Despite increasing knowledge of clinical immunological features underlying 1,4−6 biological variables explaining course its severity remain elusive. At entry site SARS-CoV2, oropharyngeal microbiome represents hub integrating viral...