- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Cardiovascular and exercise physiology
- Long-Term Effects of COVID-19
- Amyotrophic Lateral Sclerosis Research
- Health and Wellbeing Research
- Heart Rate Variability and Autonomic Control
- Public Health and Nutrition
- Neurogenetic and Muscular Disorders Research
- Hemodynamic Monitoring and Therapy
- Health and Well-being Studies
- Respiratory and Cough-Related Research
- Fluid Dynamics and Mixing
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Adipokines, Inflammation, and Metabolic Diseases
- Nursing Diagnosis and Documentation
- Gastroesophageal reflux and treatments
- Industrial Automation and Control Systems
- Water Quality Monitoring Technologies
- Dysphagia Assessment and Management
- Non-Invasive Vital Sign Monitoring
- Atomic and Subatomic Physics Research
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2014-2024
Universidade Federal de São Paulo
2013-2022
Universidade de São Paulo
2015-2022
Hospital São Paulo
2021
Universidade Federal do Pampa
2020
Universidade Cruzeiro do Sul
2020
Universidade de Mogi das Cruzes
2020
Impairment of (inspiratory and expiratory) respiratory muscles is a common clinical finding, not only in patients with neuromuscular disease but also primary the lung parenchyma or airways. Although such impairment common, its recognition usually delayed because signs symptoms are nonspecific late. This recognition, even lack thereof, occurs diagnostic tests used assessment muscle strength widely known available. There various methods assessing during inspiratory expiratory phases. These...
Most patients with unilateral diaphragm paralysis (UDP) have unexplained dyspnea, exercise limitations, and reduction in inspiratory muscle capacity. We aimed to evaluate the generation of pressure each hemidiaphragm separately its contribution overall strength.Twenty-seven patients, 9 right group (RP) 18 left (LP), forced vital capacity (FVC) < 80% pred, 20 healthy controls (CG), expiratory volume 1 s (FEV1) > pred FVC were evaluated for lung function, maximal (MIP) (MEP) measurements,...
Introduction COPD and interstitial lung disease (ILD) are significant chronic respiratory disorders, impacting quality of life. Respiratory muscle roles differences remain not entirely clear. The objective the present study was to evaluate degree recruitment muscles work breathing in ILD during exercise. Methods We compared sensory–mechanical relationships COPD, healthy controls (n=20 each). They performed pulmonary function, noninvasive invasive strength, surface electromyography...
To measure the oxygen and ventilatory output across all COPD stages performing 18 common ADL identify activities that present highest metabolic as well to compare energy expenditure within each disease severity.Metabolic (VO2 VCO2), (f VE), cardiovascular (HR) dyspnea (Borg score) variables were assessed in one hundred patients during completion of eighteen grouped into four domains: rest, personal care, labor efforts.The with proportional (VO2/VO2max VE/MVV) walking 2.5 Kg hand 5.0 hand....
Background. Comprehensive exercise training (CET) is an efficient strategy to decrease dyspnea perception in chronic obstructive pulmonary disease (COPD) and may result significant improvement ventilatory muscles function. Our aim was evaluate the effects of general on respiratory strength COPD patients. Methods. Consecutive patients were enrolled complete a CET programme. The underwent routine that included global warm up, upper lower limbs endurance as well stretching relaxation. Before...
<h3>BACKGROUND:</h3> Most patients on long-term oxygen therapy use stationary delivery systems. It is not uncommon for guidelines to instruct tubing lengths no longer than 19.68 ft (6 m) when using an concentrator and 49.21 (15 cylinders. However, these concepts are based sufficient evidence. Thus, our objective was evaluate whether a 98.42-ft (30-m) length affects flow F<sub>IO<sub>2</sub></sub> from 1 cylinder 2 concentrators. <h3>METHODS:</h3> The 3 systems were randomly selected, 1, 3, 5...
Patients with unilateral diaphragmatic paralysis (UDP) may present dyspnoea without specific cause and limited ability to exercise. We aimed investigate the diaphragm contraction mechanisms nondiaphragmatic inspiratory muscle activation during exercise in patients UDP, compared healthy individuals.Pulmonary function, as well volitional nonvolitional strength were evaluated 35 20 subjects. Respiratory pressures electromyography of scalene sternocleidomastoid muscles continuously recorded...
Contextualization: Hypertension is a disease that essentially affects the balance of vasodilator and vasoconstrictor mechanisms, causing an increase in vessels blood pressure may compromise tissue irrigation cause damage to organs. Cases develop severe clinical presentation affect sleep quality life patients. Objective: To evaluate whether aquatic therapy has beneficial effect on patients with hypertension. Method: All completed Berlin, Epworth, Minichal Pittsburgh questionnaires, Hospital...
Limited information is available regarding the role of anaerobic metabolism capacity on GOLD 1 and 2 COPD patients during upper limb exercise. We aimed to compare power capacity, blood lactate concentration, cardiovascular respiratory responses, in male versus healthy subjects 30-s Wingate test (WAnT). The rate fatigue time constant output decay (τ, tau) were also calculated a regression analysis model was built assess predictors τ these patients. Twenty-four (post-bronchodilator FEV1 73.2 ±...
<b>Introduction:</b> Pulmonary rehabilitation (PR) has a central role in treating subjects with chronic respiratory disease. However, the effects of PR recovery infected COVID-19 remains poorly understood. <b>Objective:</b> To evaluate impact 12 weeks program (PRP) on functional status, muscle force, postural balance, and symptoms anxiety depression COVID. <b>Methods:</b> Subjects hospitalized due to severe were assessed. Participants assessed by status (6-MWT) post-COVID-19 scale (PCFS),...
<b>Rationale:</b> Dyspnea and augmented ventilatory muscle constrain are important determinants for exercise cessation in mainly severe COPD. However, these mechanisms were not fully evaluated mild patients (FEV<sub>1</sub>> 50% pred). <b>Objectives:</b> To evaluate the work, recruitment of inspiratory expiratory muscles dyspnea, at rest during maximum test, COPD compared to healthy controls. <b>Methods:</b> Cross-sectional study involving 12 50%pred) (FEV<sub>1</sub>< pred) COPDs, We...
Thoracoabdominal asynchrony (TAA) is defined as the no coincident motion of ribcage (RC) and abdomen (AB). It estimated by respiratory inductive plethysmography (RIP), recently with optoelectronic (OEP). The agreement TAA measurements both remains unknown. <b>OBJECTIVE:</b> to compare RIP OEP. <b>METHODS:</b> 9 healthy subjects; interstitial lung disease (ILD) (FVC<sub>1</sub> 57.2±10.8%pred) COPD patients (FEV<sub>1</sub>38±12.6%pred) performed 2 cycle ergometer tests 30 minutes between...
<b>Background:</b> Ultrasound (US) is a simple and reproducible method of assessing diaphragmatic mobility thickness. However, the correlation between US measurements, muscle strength, FVC FEV1 are not fully established even in healthies. <b>Aims:</b> To describe right mobility, thickness fraction evaluated by US; investigate these parameters with ventilatory strength spirometry. <b>Methods:</b> In cross-sectional study, 28 healthy volunteers performed spirometry hemidiaphragmatic...
<b>Background:</b> respiratory muscle dysfunction may contribute to exercise limitation in interstitial lung disease (ILD). Diaphragmatic was demonstrated by ultrasound (US) ILD patients. However, diaphragmatic described on US not correlated with functional parameters. <b>Aims:</b> correlate patients, mobility and thickness rest dyspnea, performance 6-minute-walk test (6MWT) quality of life (QOL). <b>Methods:</b> 28 controls 24 patients performed spirometry diaphragm evaluate deep breathing...
<b>Background:</b> Respiratory muscle weakness can contribute to limit exercise. However, respiratory recruitment and exercise-induced is not fully described even in healthies. <b>Objectives:</b> To describe the of muscles thoraco-abdominal synchrony at rest during exercise healthy subjects; measure non-volitive strenght after <b>Methods:</b> 42 healthies separated two groups: 20-39 (A) 40-59 y (B) underwent maximal cycle test. Esophageal (Pes), gastric (Pgas) transdiaphragmatic pressures...
<b>Introduction:</b> Total diaphragmatic strength is the result of contribution each hemidiaphragm. However, it unclear if this similar for both diaphragms or there a disparity. Moreover, compartmental behavior has not been investigated in patients with hemidiaphragm paralysis (HDP). <b>Objectives:</b> Evaluate total and its hemi compartments (right left) during phrenic twitch stimulation (Tw) controls HDP patients. <b>Methods:</b> 9 left diaphragm paralyis (LDP) (7male, 55.7±11.6 y) 16...
<b>INTRODUCTION:</b> Pulmonary ventilation is decreased in patients with hemidiaphragmatic paralysis (HDP) and changes regional breathlessness caused by different body positions not clear. <b>OBJECTIVE:</b> Describe the distribution HDP at compare to controls. <b>METHODS:</b> 9 left (7 male, 55,7±11,6 y) 8 male healthy volunteers (27.6±3.7 underwent electrical impedance tomography (EIT) measure (LV) right (RV) during quiet breathing on diferent positions: seated, (LLD) (RLD) lateral...