A5070799152- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Gastric Cancer Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Migration, Health and Trauma
- Aortic Disease and Treatment Approaches
- Racial and Ethnic Identity Research
- Primary Care and Health Outcomes
- Air Quality and Health Impacts
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Climate Change and Health Impacts
- Cardiovascular Health and Risk Factors
- Genetic factors in colorectal cancer
- Cultural Competency in Health Care
- Nutrition, Genetics, and Disease
- Food Security and Health in Diverse Populations
- Aortic aneurysm repair treatments
- Health Policy Implementation Science
- Medical Education and Admissions
- Public Health Policies and Education
- Cardiac, Anesthesia and Surgical Outcomes
- Experimental Learning in Engineering
- Career Development and Diversity
- Health Sciences Research and Education
University of Chicago
2015-2024
University of Michigan
2010-2024
Penn State Milton S. Hershey Medical Center
2024
The University of Texas at Austin
2024
Dell Children's Medical Center of Central Texas
2024
University at Buffalo, State University of New York
2016-2023
Columbia University
2023
Los Angeles County Department of Health Services
2023
Faculty of 1000 (United States)
2020-2023
RELX Group (United States)
2020-2023
There is little evidence regarding which factors and strategies are associated with high proportions of underrepresented minority (URM) faculty in academic medicine. The authors conducted a national study U.S. medicine departments to better understand the challenges, successful strategies, predictive for enhancing racial ethnic diversity among (i.e., physicians an position or rank).
Background: Thoracic aortic dissection is an emergent life-threatening condition. Routine screening for genetic variants causing thoracic not currently performed patients or family members. Methods: We whole exome sequencing of 240 with (n=235) rupture (n=5) and 258 controls matched age, sex, ancestry. Blinded to case-control status, we annotated in 11 genes pathogenicity. Results: Twenty-four pathogenic 6 (COL3A1, FBN1, LOX, PRKG1, SMAD3, TGFBR2) were identified 26 individuals, representing...
The identity of Na+/H+ exchanger (NHE) isoforms in the human small intestine and colon their role vectorial Na+ absorption are not known. present studies were undertaken to examine regional vertical axis distribution NHE-1, NHE-2, NHE-3 mRNA intestine. Ribonuclease protection assays used quantitate levels these various regions In situ hybridization technique was localize NHE-2 colon. NHE-1 isoform message uniformly throughout length contrast, for demonstrated significant differences....
American ginseng is a commonly used herbal medicine in the United States. When taken orally, its active components, ginsenosides, are reportedly biotransformed by intestinal microbiota. Previous pharmacokinetic evaluations of humans have focused on parent constituents. However, metabolites, especially those transformed microbiota, not been carefully studied. We an ultra-performance liquid chromatography/time-of-flight mass spectrometry (UPLC/TOF-MS) method to determine 15 ginsenosides and/or...
Abstract Background Many evidence-based interventions (EBIs) found to be effective in research studies often fail translate into meaningful patient outcomes practice. The purpose of this study was identify facilitators and barriers that affect the implementation three EBIs improve colorectal cancer (CRC) screening an urban federally qualified health center (FQHC) offer actionable recommendations future efforts. Methods We conducted 16 semi-structured interviews guided by Consolidation...
Background: The short-term efficacy and safety of the Y-incision technique aortic annular enlargement (AAE) has been established. We aimed to determine how outcomes compared traditional AAE techniques. Methods: From February 2011 June 2022, 380 patients at University Michigan Hospital underwent valve replacement (AVR) with using either techniques (Traditional group, n=270), including Nicks [63% (171/270)], Manouguian [34% (91/270)], others [3% (8/270)], or (Y-incision n=110). Propensity...
Socioeconomically disadvantaged subpopulations are more vulnerable to fine particulate matter (PM2.5) exposure. However, as prior studies focused on individual-level socioeconomic characteristics, how contextual deprivation modifies the association of PM2.5 exposure with cardiovascular health remains unclear.
Abstract Background Western diets increase colon cancer risk. Epidemiological evidence and experimental studies suggest that ginseng can inhibit development. In this study we asked if could diet (20% fat) promoted colonic tumorigenesis compound K, a microbial metabolite of suppress xenograft growth. Methods Mice were initiated with azoxymethane (AOM) and, two weeks later fed (WD, 20% alone, or WD supplemented 250-ppm ginseng. After 1 wk, mice received 2.5% dextran sulfate sodium (DSS) for 5...
The United States commemorates National Hepatitis Awareness Month each May, and May 19 is designated as Testing Day.Viral hepatitis still persists a major public health threat despite availability of preventive measures such vaccines therapies, including curative treatment for C virus (HCV) infection.New cases B (HBV) HCV infections are on the rise, largely among persons who inject drugs, with some attributed to current U.S. opioid epidemic (1).Recent A outbreaks have also occurred...
Abstract Background: The Center to Reduce Cancer Health Disparities (CRCHD), National Institute (NCI), launched Screen Save, NCI's Colorectal Outreach and Screening Initiative promote awareness knowledge of colorectal cancer in racial/ethnic rural populations. Methods: initiative was implemented through CRCHD's Network (NON) Comprehensive Partnerships Advance Equity (CPACHE) programs. NON is a national network Community Educators (CHEs), aligned with NCI-designated Centers (CCs). CPACHE are...
Hepatitis B (HBV) is an urgent, unmet public health issue that affects Asian Americans disproportionately. Of the estimated 1.2 million living with chronic hepatitis in USA, more than 50% are of ethnicity, despite fact constitute less 6% total US population. The Centers for Disease Control and Prevention recommends HBV screening persons who at high risk disease. Yet, large numbers have not been diagnosed or tested, part because perceived cultural linguistic barriers. Primary care physicians...
Abstract Introduction The NIH All of Us Research Program has enrolled over 544,000 participants across the US with unprecedented racial/ethnic diversity, offering opportunities to investigate myriad exposures and diseases. This paper aims association between PM 2.5 exposure cancer risks. Materials methods work was performed on data from 409,876 using Researcher Workbench. Cancer case ascertainment electronic health records self-reported Personal Medical History questionnaire. retrieved...
Introduction The NIH All of Us Research Program will have the scale and scope to enable research for a wide range diseases, including cancer. program’s focus on diversity inclusion promises better understanding unequal burden Preliminary cancer ascertainment in cohort from two data sources (self-reported versus electronic health records (EHR)) is considered. Materials methods This work was performed collected Program’s 315,297 enrolled participants date using Researcher Workbench, where...
This study aimed to investigate the joint effect of neighborhood disadvantages on asthma prevalence and evaluate whether individual-level variables protect residents against disadvantages. Data from Chicago Multiethnic Prevention Surveillance Study (from 2013-2020) were analyzed. Eight characteristics measured using Health Atlas, including unsafety, limited access healthy food, alienation, severe rent burden, vacant housing, single-parent household, poverty, unemployment. A structured...
Shared decision making (SDM) is a model of patient-provider communication. Little known about the role SDM in health disparities among Asian American and Pacific Islander (AAPI) sexual gender minorities (SGM). We illustrate how issues at intersection AAPI SGM identities affect processes outcomes. discuss experiences that are affected by heterogeneity, stigma, multiple minority group identities, sources discrimination. Recommendations for clinical practice, research, policy, community...