Xinyu Zhang

ORCID: 0000-0003-3472-8393
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Toxic Organic Pollutants Impact
  • Effects and risks of endocrine disrupting chemicals
  • Carcinogens and Genotoxicity Assessment
  • High Entropy Alloys Studies
  • Additive Manufacturing Materials and Processes
  • Air Quality and Health Impacts
  • Intermetallics and Advanced Alloy Properties
  • High-Temperature Coating Behaviors
  • Synthesis and Biological Evaluation
  • Radiation Detection and Scintillator Technologies
  • Microplastics and Plastic Pollution
  • Environmental Toxicology and Ecotoxicology
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Advanced Photocatalysis Techniques
  • Nephrotoxicity and Medicinal Plants
  • Nuclear Physics and Applications
  • Ferroptosis and cancer prognosis
  • Cancer-related molecular mechanisms research
  • Luminescence Properties of Advanced Materials
  • Heavy metals in environment
  • Sulfur Compounds in Biology
  • Genomics, phytochemicals, and oxidative stress
  • nanoparticles nucleation surface interactions
  • Heavy Metal Exposure and Toxicity
  • Titanium Alloys Microstructure and Properties

Shanghai Ninth People's Hospital
2016-2025

Shanghai Jiao Tong University
2016-2025

Shanghai Eye Disease Prevention & Treatment Center
2023-2025

Shanghai First People's Hospital
2023-2025

Nanjing Agricultural University
2024-2025

Tsinghua University
2025

Hebei Medical University
2025

Ministry of Agriculture and Rural Affairs
2025

Center for Disease Control
2025

Shanghai University
2010-2024

Objective Microbiota disorder promotes chronic inflammation and carcinogenesis. High glycolysis is associated with poor prognosis in patients colorectal cancer (CRC). However, the potential correlation between gut microbiota glucose metabolism unknown CRC. Design 18 F-FDG ( F-fluorodeoxyglucose) PET (positron emission tomography)/CT image scanning data PCR analysis were performed to measure metabolic alterations 33 Multiple models, Seahorse assay established assess role of long non-coding...

10.1136/gutjnl-2020-322780 article EN Gut 2020-12-14

The chemokine ligand C-X-C motif 11 (CXCL11) is involved in the progression of various cancers, but its biological roles colorectal cancer (CRC) remain confused. Therefore, prognostic value and underlying mechanism CXCL11 CRC were preliminarily evaluated. Three independent datasets used for mRNA-related analysis: one dataset from Cancer Genome Atlas (TCGA, n = 451) two single-cell RNA sequencing (scRNA-seq) Gene Expression Omnibus (GEO): GSE146771 GSE132465. In addition, a colon...

10.3389/fcell.2021.646252 article EN cc-by Frontiers in Cell and Developmental Biology 2021-03-11

As a marker for oxidative stress and second messenger in signal transduction, hydrogen peroxide (H2O2) plays an important role living systems. It is thus critical to monitor the changes H2O2 cells tissues. Here, we developed highly sensitive versatile ratiometric fluorescent probe (NP1) based on 1,8-naphthalimide boric acid ester. In response H2O2, ratio of its intensities at 555 403 nm changed 1020-fold within 200 min. The detecting limit NP1 toward estimated as 0.17 μM. was capable imaging...

10.1021/ac502909c article EN Analytical Chemistry 2014-09-08

Microplastics (MPs) generally refer to the plastic fragments or particles smaller than 5 mm in diameter, which are closely concerned due their widespread presence environment. Recent studies have shown that MPs a serious threat on reproductive health of organisms. Pigs often selected as model animals because high similarity human tissues and organs. However, there no reports effects mechanisms exposure swine germ cells. In present study, we established testis (ST) cell models exposed 250,...

10.1002/tox.23611 article EN Environmental Toxicology 2022-07-06

While boron nitride (BN) is widely recognized as the most promising thermally conductive filler for rapidly developing high-power electronic devices due to its excellent thermal conductivity and dielectric properties, a great challenge poor vertical when embedded in composites owing interfacial interaction causing severe phonon scattering. Here, we report novel surface modification strategy called "self-modified nanointerface" using BN nanocrystals (BNNCs) efficiently link interface between...

10.1007/s40820-022-00972-9 article EN cc-by Nano-Micro Letters 2022-11-28

Rural landscapes have significant ecological, historical, and cultural value including numerous green spaces forest that should be protected utilized. With the growing demand for tourism in rural areas recent years, greenways become increasingly crucial promoting urban–rural development by connecting linear spatial corridors such as landscape patches, scenic pathways, strip woodlands. The accuracy universality of visual quality assessment affect construction enhancement landscapes. previous...

10.1016/j.ecolind.2024.111844 article EN cc-by-nc Ecological Indicators 2024-03-01

The long noncoding RNA (lncRNA) colon cancer–associated transcript–1 (CCAT1) has been reported to play a vital role in the development of cancer. Although link between inflammation and cancer initiation is well established, whether CCAT1 involved promotes inflammatory bowel disease (IBD) malignancy remains undetermined. We aimed investigate expression IBD effect overexpression on intestinal epithelial barrier function. relationship inflammation-related pathway was analyzed both colorectal...

10.1093/ibd/izy381 article EN Inflammatory Bowel Diseases 2019-01-04

Achieving high strength and ductility simultaneously in high-entropy alloys (HEAs) has always been a challenge, recent studies indicate that duplex microstructure provides strategy to solve this contradiction. We prepared Al0.25FeCoNiV HEA with L12/B2 fine-grain achieved remarkable combination of the ultimate tensile (1530 MPa) (20%), which clearly outperforms other HEAs. Owing formation hindrance B2 phase, yield achieved. Furthermore, excellent work-hardening ability L12 phase dispersion...

10.1080/21663831.2022.2093140 article EN cc-by Materials Research Letters 2022-07-03
Coming Soon ...