A5103027196- Glioma Diagnosis and Treatment
- TGF-β signaling in diseases
- Adipose Tissue and Metabolism
- Renal and related cancers
- Liver Disease Diagnosis and Treatment
- Fatty Acid Research and Health
- Migration, Health and Trauma
- Cancer, Lipids, and Metabolism
- Diet, Metabolism, and Disease
- Exercise and Physiological Responses
- Peroxisome Proliferator-Activated Receptors
- Pancreatic function and diabetes
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Prenatal Substance Exposure Effects
- Muscle metabolism and nutrition
- Microfluidic and Capillary Electrophoresis Applications
- Vitamin C and Antioxidants Research
- Lipid metabolism and biosynthesis
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Neurological Complications and Syndromes
- Tea Polyphenols and Effects
- Biomarkers in Disease Mechanisms
- Innovative Microfluidic and Catalytic Techniques Innovation
- Meat and Animal Product Quality
- RNA modifications and cancer
Université de Lille
2021-2024
Centre Oscar Lambret
2023-2024
Inserm
2023-2024
Université Claude Bernard Lyon 1
2023
Convergence
2023
Hospital Sant Joan de Déu Barcelona
2023
Hôpital Femme Mère Enfant
2023
Centre Hospitalier Universitaire de Lille
2023
Centre de Recherche en Cancérologie de Marseille
2023
Centre National de la Recherche Scientifique
2023
This study aimed to investigate the influence of localized muscle cooling on postexercise vascular, metabolic, and mitochondrial-related gene expression.Nine physically active males performed 30 min continuous running at 70% their maximal aerobic velocity, followed by intermittent exhaustion 100% velocity. After exercise, subjects immersed one leg in a cold water bath (10°C, COLD) level gluteal fold for 15 min. The contralateral remained outside served as control (CON). Core body temperature...
Abstract Background Non alcoholic steatohepatitis is hypothesised to develop via a mechanism involving fat accumulation and oxidative stress. The current study aimed investigate if an increase in stress was associated with changes the expression of liver fatty acid binding protein rat model non whether cocoa supplementation attenuated those changes. Methods Female Sprague Dawley rats were fed high control diet, methionine choline deficient or one four 12.5% regimes combination diet. Results...
Artificially increasing dopamine transmission is the common mechanism by which substances with addictive potential lead to addiction. A key area of research in neurobiology role dopamine. Significant advancements have been made uncovering intracellular signaling pathways that mediate both dopamine’s immediate effects and its long-term influence on brain function. Recent discoveries also highlighted specific molecules could serve as therapeutic targets for neurological psychiatric...
Fish oil is commonly taken by pregnant women, and supplements sold at retail are often oxidized. Using a rat model, we aimed to assess the effects of supplementation with oxidized fish during pregnancy in mothers offspring, focusing on newborn viability maternal insulin sensitivity. Female rats were allocated control or high-fat diet then mated. These subsequently randomized receive daily gavage treatment 1 ml unoxidized oil, highly (water) throughout pregnancy. At birth, was stopped, but...
This study investigated the effect of dietary manipulations on muscle fatty acid composition, activities and relative mRNA expressions antioxidant enzymes relationship between enzyme activity or expression alpha linolenic (ALA) concentration in sheep. Eighty-four lambs blocked liveweight were randomly allocated to four treatments, lucerne pasture (Lucerne), annual ryegrass (Ryegrass), feedlot pellets (Feedlot) plus (RyeFeedlot). After six weeks feeding, slaughtered within 30 min post-mortem,...
Pediatric diffuse midline gliomas (pDMG) are an aggressive type of childhood cancer with a fatal outcome. Their major epigenetic determinism has become clear, notably the identification K27M mutations in histone H3. However, synergistic oncogenic mechanisms that induce and maintain tumor cell phenotype have yet to be deciphered. In 20 30% cases, these tumors altered BMP signaling pathway mutation on I receptor ALK2, encoded by ACVR1 . potential impact non-mutated for is less clear. By...
This study aimed to determine if 50 days of canola oil intake in the absence or presence salt loading affects: (1) antioxidant and oxidative stress markers, (2) aortic mRNA NADPH oxidase (NOX) subunits superoxide dismutase (SOD) isoforms (3) endothelial function SHRSP rats. rats were fed a diet containing 10 wt/wt% soybean oil, given tap water 1% NaCl for days. Without salt, significantly increased RBC SOD, plasma cholesterol triglycerides, p22 (phox) , NOX2 CuZn-SOD mRNA, decreased...
We examined the effects of leptin treatment on expression key genes in adipocyte metabolism Psammomys obesus (P. obesus), a polygenic rodent model obesity. Lean and obese P. were given three daily intraperitoneal injections either saline or (total 45 mg/kg per day) for 7 days. In lean animals, led to reductions food intake, body weight fat mass. Pair-fed animals matched reduction intake leptin-treated demonstrated similar obesus, failed have any effect mass, indicating resistance....
Pediatric diffuse midline gliomas (pDMG) are an aggressive type of childhood cancer with a fatal outcome. Their major epigenetic determinism has become clear, notably the identification K27M mutations in histone H3. However, synergistic oncogenic mechanisms that induce and maintain tumor cell phenotype have yet to be deciphered. In 20 30% cases, these tumors altered BMP signaling pathway mutation on I receptor ALK2, encoded by ACVR1 . potential impact non-mutated for is less clear. By...
Abstract Pediatric diffuse midline gliomas (pDMG) are an aggressive type of childhood cancer with a fatal outcome. Their major epigenetic determinism has become clear, notably the identification K27M mutations in histone H3. However, synergistic oncogenic mechanisms that induce and maintain tumor cell phenotype have yet to be deciphered. In 20 30% cases, these tumors altered BMP signaling pathway mutation on I receptor ALK2, encoded by ACVR1. potential impact non-mutated for ACVR1 is less...
Pediatric diffuse midline gliomas (pDMG) are an aggressive type of childhood cancer with a fatal outcome. Their major epigenetic determinism has become clear, notably the identification K27M mutations in histone H3. However, synergistic oncogenic mechanisms that induce and maintain tumor cell phenotype have yet to be deciphered. In 20 30% cases, these tumors altered BMP signaling pathway mutation on I receptor ALK2, encoded by ACVR1. potential impact non-mutated for ACVR1 is less clear. By...
Pediatric diffuse midline gliomas (pDMG) are an aggressive type of childhood cancer with a fatal outcome. Their major epigenetic determinism has become clear, notably the identification K27M mutations in histone H3. However, synergistic oncogenic mechanisms that induce and maintain tumor cell phenotype have yet to be deciphered.In 20 30% cases, these tumors altered BMP signaling pathway mutation on I receptor ALK2, encoded by ACVR1. potential impact non-mutated for ACVR1 is less clear. By...