Layana Costa Alves

ORCID: 0000-0003-3512-7872
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About
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Research Areas
  • Tuberculosis Research and Epidemiology
  • Poverty, Education, and Child Welfare
  • Child Nutrition and Water Access
  • Health Systems, Economic Evaluations, Quality of Life
  • Healthcare Systems and Reforms
  • Global Maternal and Child Health
  • Health, Nursing, Elderly Care
  • COVID-19 epidemiological studies
  • COVID-19 Clinical Research Studies
  • COVID-19 and healthcare impacts
  • COVID-19 and Mental Health
  • COVID-19 diagnosis using AI
  • Homelessness and Social Issues
  • HIV/AIDS Impact and Responses
  • Global Health and Epidemiology
  • Employment and Welfare Studies
  • Healthcare cost, quality, practices
  • Disaster Response and Management
  • COVID-19 Pandemic Impacts
  • Viral Infections and Outbreaks Research
  • Global Public Health Policies and Epidemiology
  • Chronic Disease Management Strategies
  • Immune responses and vaccinations
  • Diagnosis and treatment of tuberculosis
  • Physical Education and Gymnastics

Universidade Federal da Bahia
2021-2025

Universidade de Itaúna
2024

Ministry of Health
2024

Ministério da Saúde
2022-2024

Ministério da Saúde
2021-2023

Instituto de Saúde
2022-2023

Universidade de Brasília
2021-2022

Fundação Oswaldo Cruz
2011-2021

Disruptions in tuberculosis services have been reported around the world since emergence of COVID-19 pandemic. However, pandemic's effect on preventive treatment (TPT) has poorly explored. We compared TPT-notified prescriptions and outcomes before during pandemic Brazil. Retrospective cohort using secondary data from Brazilian TPT information system five cities with over 1000 notifications. The number was analysed 6 months after healthcare workers' training, 2018, to July 2021. proportion by...

10.1016/j.lana.2023.100444 article EN cc-by-nc-nd The Lancet Regional Health - Americas 2023-02-10

Tuberculosis (TB) is the leading infectious disease cause of death worldwide. In recent years, stringent measures to contain spread SARS-CoV-2 have led considerable disruptions healthcare services for TB in many countries. The extent which these affected testing, treatment initiation and outcomes has not been comprehensively assessed. We aimed estimate service occurring during COVID-19 pandemic Brazil, India, South Africa. obtained country-level programme laboratory data used autoregressive...

10.1371/journal.pgph.0003309 article EN cc-by PLOS Global Public Health 2025-01-07

Almost 200,000 deaths from COVID-19 were reported in Brazil 2020. The case fatality rate of a new infectious disease can vary by different risk factors and over time. We analysed the trends associated rates Brazilian public hospital admissions during first wave pandemic.A retrospective cohort all COVID-19-related between epidemiological weeks 10-40 Public Health System (SUS) was delimited available reimbursement records. Smoothing time series survival analyses conducted to evaluate (CFR)...

10.1371/journal.pone.0254633 article EN cc-by PLoS ONE 2021-07-16

Background In Brazil, many individuals with tuberculosis (TB) do not receive appropriate care due to delayed or missed diagnosis, ineffective treatment regimens, loss-to-follow-up. This study aimed estimate the health losses and TB program costs attributable each gap in cascade for disease Brazil. Methods findings We constructed a Markov model simulating lifetime outcomes (e.g., death, cure, postinfectious sequelae) developing stratified by age, human immunodeficiency virus (HIV) status,...

10.1371/journal.pmed.1004361 article EN cc-by PLoS Medicine 2024-03-21

Individuals who were formerly incarcerated have high tuberculosis incidence, but are generally not considered among the risk groups eligible for prevention. We investigated potential health impact and cost-effectiveness of Mycobacterium infection screening preventive treatment (TPT) individuals in Brazil. Using published evidence Brazil, we constructed a Markov state transition model estimating tuberculosis-related outcomes costs incarcerated, by simulating transitions between states over...

10.1016/s2214-109x(24)00221-3 article EN cc-by The Lancet Global Health 2024-08-14

Abstract Background Malaria causes 400 thousand deaths worldwide annually. In 2018, 25% (187,693) of the total malaria cases in Americas were Brazil, with nearly all (99%) Brazilian Amazon region. The Bolsa Família Programme (BFP) is a conditional cash transfer (CCT) programme launched 2003 to reduce poverty and has led improvements health outcomes. CCT programmes may burden by alleviating promoting access healthcare, however this relationship underexplored. This study investigated...

10.1186/s12889-021-11255-0 article EN cc-by BMC Public Health 2021-06-29

Reliable subnational estimates of TB incidence would allow national policy makers to focus disease control resources in areas highest need. We developed an approach for generating small area incidence, and the fraction individuals missed by routine case detection, based on available notification mortality data. demonstrate feasibility this creating municipality-level burden Brazil. a mathematical model describing relationship between notifications deaths, allowing known biases each these...

10.1371/journal.pgph.0000725 article EN cc-by PLOS Global Public Health 2022-09-21

To analyse the mortality trends in children under five years old Brazil from 2017 to 2020 and influence of COVID-19 2020. A retrospective study employing secondary data Brazilian Mortality Information System. Deaths according cause were extracted disaggregated into early, late, postneonatal, 1 4-year-old periods. Corrected rates per 1,000 live births relative risk ratio for death calculated. There 34,070 deaths, being 417 (1.2%) was 0.17 1000 births, reaching 0.006 early neonatal period,...

10.1016/j.jped.2022.03.004 article EN cc-by-nc-nd Jornal de Pediatria 2022-04-20

Tuberculosis (TB) is a preventable and curable disease. In Brazil, TB treatment outcomes are particularly worse among homeless populations who either of black race, malnourished or living with HIV/AIDS other comorbidities. This study therefore evaluated factors associated unsuccessful population (HP) compared to those shelter.The was composed 284,874 people diagnosed in Brazil between 2015 2020 reported the Information System for Notifiable Diseases (SINAN), which 7,749 (2.72%) were 277,125...

10.1371/journal.pntd.0011685 article EN cc-by PLoS neglected tropical diseases 2023-10-20

<title>ABSTRACT</title> <sec> <title>Objective.</title> To analyze the temporal trend of tuberculosis incidence and mortality rates in Brazil between 2011 2019. </sec> <title>Methods.</title> This was an ecological time series study Data were extracted from Notifiable Disease Information System Mortality System, population estimates Brazilian Institute Geography Statistics. Trends analyzed by Joinpoint regression, which recognizes inflection points for analysis. <title>Results.</title> The...

10.26633/rpsp.2023.152 article EN cc-by-nc-nd Revista Panamericana de Salud Pública 2023-11-06

Abstract: Brazil was heavily affected by COVID-19 both with death toll and economically, absence of a centralized Federal Government response. Tuberculosis (TB) notifications decreased in 2020 but partial recovery observed 2021. We have previously shown sharp (93%) reduction TB preventive treatment among five Brazilian cities more than 1,000 hypothesized would also recover. updated the previous analysis adding other that hold until 2022. Data aggregated 2-week periods were extracted from...

10.1590/0102-311xen192923 article EN cc-by Cadernos de Saúde Pública 2024-01-01

To describe the profile of hospital deaths in Brazil according to cause admission during pre-pandemic (2019) and pandemic periods (2020).Descriptive study based on individual-level records all admissions with death outcomes reimbursed by Brazilian National Health System 2019 2020.The number increased 16.7% 2020 compared (522,686 vs 609,755). Coronavirus disease (COVID-19) was associated 19.5% (118,879) 2020, surpassing diseases circulatory system (15.4%, 93,735) respiratory (14.9%,...

10.1016/j.ijid.2021.09.077 article EN cc-by International Journal of Infectious Diseases 2021-10-02

Objetivou-se analisar as indicações de tratamento para tuberculose latente no sistema notificação brasileiro, 2018 a 2022. Realizou-se um estudo descritivo, com dados secundários, referentes às realizadas da Brasil, janeiro junho Foram apuradas frequências absoluta e relativa, apresentadas em mapas temáticos. registradas 85.822 notificações, sendo “contatos pessoas tuberculose” indicação mais frequente (57,2%). Como quarta comum, observou-se o campo “outra” (7,7%), reservado eventuais...

10.32811/25954482-2023v6n2.750 article PT cc-by Revista de Saúde Pública do Paraná 2023-06-20

The article seeks to assess the Brazilian health system ability respond challenges imposed by coronavirus disease 2019 (COVID-19) pandemic measuring capacity of hospitals care for COVID-19 cases in 450 Health Regions country during year 2020. Hospital refers availability hospital beds, equipment, and human resources.We used longitudinal data from National Register Facilities (CNES) regarding resources necessary patients with inpatient facilities (public or private) January December Among...

10.1017/dmp.2022.214 article EN Disaster Medicine and Public Health Preparedness 2022-08-22

Abstract Background Formerly incarcerated individuals experience high tuberculosis (TB) incidence rates but are generally not considered among risk groups eligible for TB prevention. We investigated the potential health impact and cost-effectiveness of Mycobacterium (Mtb) infection screening preventive treatment (TPT) formerly in Brazil. Methods Using published evidence Brazil, we constructed a Markov state transition model simulating TB-related outcomes costs individuals. The analysis...

10.1101/2024.01.03.23300373 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2024-01-04

Abstract Tuberculosis (TB) is the leading infectious disease cause of death worldwide. In recent years, stringent measures to contain spread SARS-CoV-2 have led considerable disruptions healthcare services for TB in many countries. The extent which these affected testing, treatment initiation and outcomes has not been comprehensively assessed. We aimed estimate service occurring during COVID-19 pandemic Brazil, India, South Africa. obtained country-level programme laboratory data used...

10.1101/2024.05.16.24307503 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2024-05-16

O Brasil apresenta polarização epidemiológica, com elevadas taxas de mortalidade por doenças crônicas não transmissíveis e alta incidência moléstias infectoparasitárias. As ações saúde devem ser desenvolvidas a partir da análise microrregional é essencial que o fisioterapeuta conheça cenário epidemiológico. OBJETIVO: mapear perfil socioeconômico, prevalência DCNT e/ou infectoparasitárias risco familiar. MÉTODOS: Estudo transversal, realizado à população atendida nas CIFs- UIT (parecer...

10.24862/cco.v19i4.2021 article PT cc-by Conexão Ciência (Online) 2024-12-04

Objective: We assessed the Brazilian health system's ability to respond challenges imposed by Covid-19 pandemic considering hospital capacity in 450 Health Regions of country 2020. Hospital referred availability beds, equipment, and human resources. Methods: Data came from National Register Facilities on resources inpatient facilities January December,2020. Assessed were professionals, medical equipment. A synthetic indicator, Installed Capacity Index (ICI) was calculated using Principal...

10.1101/2021.06.17.21259121 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-06-21

<h3>Introduction</h3> Health conditions and functionality problems related to ageing affect the ability live independently, leading placement of elders in a long-stay institution. This phenomenon has been increasing Brazil. study analyzes functional dependence its associated factors this population group. <h3>Methods</h3> is cross-sectional with elderly residents institutions four Brazilian cities. The study9s questionnaire included socio-demographic health-related variables assessment...

10.1136/jech.2011.142976n.15 article EN Journal of Epidemiology & Community Health 2011-08-01

<h3>Introduction</h3> Cognitive impairment and depression are among the health conditions that affect ability of elders to live independently, leading their placement at long-stay institutions. This phenomenon has been increasing in Brazil. study analyzes prevalence these its associated factors who <h3>Methods</h3> is a cross-sectional with elderly residents institutions four Brazilian cities. The study9s questionnaire included socio-demographic health-related variables assessment...

10.1136/jech.2011.142976m.97 article EN Journal of Epidemiology & Community Health 2011-08-01
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