A5051044519- Eosinophilic Esophagitis
- Esophageal and GI Pathology
- Gut microbiota and health
- Gastroesophageal reflux and treatments
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Diverticular Disease and Complications
- Clinical Nutrition and Gastroenterology
- Gastrointestinal motility and disorders
- Kidney Stones and Urolithiasis Treatments
- Diet and metabolism studies
- Gastric Cancer Management and Outcomes
- Phonocardiography and Auscultation Techniques
- Hepatitis C virus research
- Helicobacter pylori-related gastroenterology studies
- Clostridium difficile and Clostridium perfringens research
- Iron Metabolism and Disorders
- Engineering Diagnostics and Reliability
- Animal Virus Infections Studies
- Drug-Induced Hepatotoxicity and Protection
- Mosquito-borne diseases and control
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Tracheal and airway disorders
- Esophageal Cancer Research and Treatment
- Airway Management and Intubation Techniques
Chulalongkorn University
2018-2024
King Chulalongkorn Memorial Hospital
2019-2023
Thai Red Cross Society
2018-2023
Microbiota-dysbiosis-induced gut leakage is a pathophysiologic change in chronic kidney disease (CKD), leading to the production of several uremic toxins and their absorption into bloodstream worsen renal complications. We evaluate benefits resistant maltodextrin (RMD) chitosan oligosaccharide (COS) supplements cell culture CKD-induced rats. The RMD exerted significant anti-inflammatory effect vitro intestinal occludin zonula occluden-1 up-regulation CKD rats compared with inulin COS. While...
Acetaminophen (APAP) overdose is one of the major causes acute liver failure. Severe inflammation and production oxidative stress occur due to toxic APAP metabolites glutathione depletion. Growing evidence has proved that vitamin D (VD) exerts anti-inflammatory antioxidative functions. Our objective was explore protective role calcitriol (VD3) in APAP-induced injury. Methods: Adult male mice were randomized into three groups; control (n = 8), VD3 group 8). All mice, except controls, received...
Dyssynergic defecation (DD) is a type of functional constipation that requires specialized test for diagnosis. However, these tests are only accessible in tertiary care because they require devices not available elsewhere. In this work, we present explainable multi-modal deep learning models can pre-screen patients with DD, using affordable data small hospitals i.e. abdominal X-ray images and symptom questionnaires; the output classifies whether DD or not. To enhance model's performance,...
An increase in postprandial intestinal gas plays a role bloating symptoms. We aim to study the utility of spot breath hydrogen (H2) level predicting response low fermentable oligo-, di-, mono-saccharides, and polyols (FODMAPs) diet.Patients with functional gastrointestinal disorders diagnosed by Rome IV criteria bothersome for > 6 months were prospectively enrolled. Patients completed 7-day food diaries collected sample 2 hours after their usual lunch at baseline 4 weeks FODMAPs dietary...
Background Hepatitis B virus (HBV) pregenomic RNA (pgRNA) has gained increasing attention owing to its role in replication of covalently closed circular DNA (cccDNA) HBV. This marker the potential be used clinical programs aimed manage HBV infections. However, several reports on pgRNA levels cases have conflicting results. is easily degraded when exposed heat and other environmental stressors. stability pgRNA, during blood sample collection before standard automated quantification, never...
Helicobacter pylori (HP) infection remains a significant global public health problem. This study aimed to the prevalence of HP and treatment outcomes in Thailand.We retrospectively reviewed results urea breath test (UBT) performed at King Chulalongkorn Memorial Hospital between 2018 2021. The was evaluated dyspeptic patients undergoing UBT screening. In with known infection, regimen success rate each patient were recorded.One-thousand nine-hundred two included this study. 20.77% (UBT...
Abstract Emerging research on the microbiome highlights significant role of gut health in development kidney stones, indicating that an imbalance bacteria, or dysbiosis, can influence formation stones by altering oxalate metabolism and urinary metabolite profiles. Notably, presence specific bacteria such as Enterococcus Oxalobacter spp., known to affect absorption, is linked urolithiasis, prompting further investigation into gut's calcium stone disease. This study investigates effects...
Chronic kidney disease (CKD) affects more than 850 million people worldwide, contributing to morbidity and mortality, particularly through cardiovascular (CVD). The altered composition in CKD patients leads increased production absorption of uremic toxins such as trimethylamine (TMA) its oxidized form, N-oxide (TMAO), which are associated with risks. This study investigated the potential supplementary interventions high-carotenoid-content gac fruit extract probiotics mitigate serum TMAO by...
Patients are required to undergo specialized tests for dyssynergic defecation diagnosis. However, these limited tertiary healthcare centers. The aim of this paper is prescreen potential patients from primary and secondary centers further diagnostic by using easily obtainable data. We proposed an integrated model which utilizes symptom questionnaire abdominal radiograph. First, we applied some the most popular tree-based machine learning algorithms on questionnaire. best set features was...
Abstract Background Gastrointestinal stromal tumor (GIST) was the most common mesenchymal of gastrointestinal tract predominately occurring in stomach. Although GIST a rare disease, it considered to be life-threatening malignancy. Objective To explore current status gastric Thai patients. Method The medical records patients who were diagnosed with histologically proven from 2012 2016 King Chulalongkorn Memorial Hospital reviewed. Results Of 22 patients, there 14 (63.6%) females and 8 (36.4%)...