A5061210786- Fibroblast Growth Factor Research
- Epigenetics and DNA Methylation
- Dietary Effects on Health
- Circadian rhythm and melatonin
- Diagnosis and Treatment of Venous Diseases
- Thermoregulation and physiological responses
- Menopause: Health Impacts and Treatments
- Bariatric Surgery and Outcomes
- Birth, Development, and Health
- Psychological and Temporal Perspectives Research
- Kruppel-like factors research
- Cancer, Hypoxia, and Metabolism
- Gestational Diabetes Research and Management
- Genetic Syndromes and Imprinting
- Human Health and Disease
- Growth Hormone and Insulin-like Growth Factors
- Hormonal and reproductive studies
North-Western State Medical University named after I.I. Mechnikov
2018-2020
Fibroblast Growth Factor 21 (FGF21) regulates mainly glucose and lipid metabolism. It improves insulin sensitivity, increases high-density lipoprotein, decreases serum triglyceride, low-density blood level body weight. However, high circulating FGF21 levels have been found in the case of type 2 diabetes, chronic heart disease, non-alcoholic fatty liver obesity other. These findings may indicate resistance or compensatory response to metabolic stress. Thus, can be seen as a potential marker...
To investigate the impact of fibroblast growth factor 21 (FGF-21) on severity androgen deficiency in young and middle-aged men with type 2 diabetes mellitus.The study comprised 100 mellitus, cardiovascular multi-morbidity, obesity (study group) 20 healthy aged 35-50 years. The group was further divided into two subgroups. Patients subgroup 1 received standard treatment for disease. were treated conventional therapy concurrently testosterone undecanoate. baseline examination included...
Objective: To evaluate the possibility of using fibroblast growth factor 21 (FGF 21) as a marker metabolic disorders and premature aging in polymorbid cardiovascular pathology. Research methods: 199 men aged 35-55 years who were stratified into 3 groups examined: group A - 117 patients with type 2 diabetes mellitus (type diabetes), disease (PCVD), obesity, androgen deficiency anxiety-depressive (ADD); B 55 PCVD, obesity ADD; C control (n = 27). The examination included laboratory study level...
Objective. To evaluate melatonin (MT) excretion patterns in patients with polymorbid cardiovascular diseases (coronary artery disease, hypertension, metabolic syndrome), anxiety and depressive disorders, to determine the targets for therapeutic intervention this group of patients. Design methods . The study included 40 men (mean age — 37,11 ± 6,93 years) 10 healthy 37,5 4,95 years). We used complex psychological test methods, laboratory tests instrumental evaluation system....
BACKGROUND: Gestational diabetes mellitus is a significant medical and social problem in most countries. Despite the relatively high level of development modern medicine, following growth obesity type 2 diabetes, prevalence gestational also increasing worldwide.
 AIM: To identify frequency structure carbohydrate metabolism disorders to compare blood pressure random sample pregnant women registered Perinatal center.
 MATHERIALS AND METHODS: The analysis data examination who are...