A5051607689- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Antimicrobial Peptides and Activities
- Advancements in Transdermal Drug Delivery
- Gut microbiota and health
- Wound Healing and Treatments
- RNA and protein synthesis mechanisms
- Oral microbiology and periodontitis research
- Tryptophan and brain disorders
- Antibiotic Use and Resistance
- Infective Endocarditis Diagnosis and Management
- Pharmaceutical and Antibiotic Environmental Impacts
- Sinusitis and nasal conditions
- Streptococcal Infections and Treatments
- Microbial infections and disease research
- Burn Injury Management and Outcomes
- Bacterial Genetics and Biotechnology
- Bacteriophages and microbial interactions
- Tuberculosis Research and Epidemiology
- Bacterial Identification and Susceptibility Testing
- Bacterial Infections and Vaccines
- Phenothiazines and Benzothiazines Synthesis and Activities
- Enterobacteriaceae and Cronobacter Research
- PARP inhibition in cancer therapy
- Nasal Surgery and Airway Studies
Hamedan University of Medical Sciences
2022-2025
Shahrekord University of Medical Sciences
2019
Abstract Background Pseudomonas aeruginosa is an opportunistic pathogen in the health-care systems and one of primary causative agents with high mortality hospitalized patients, particularly immunocompromised. The limitation effective antibiotic administration multidrug-resistant extensively drug-resistant P. isolates leads to development nosocomial infections health problems. Quorum sensing system contributes biofilm formation, expression bacterial virulence factors, drug resistance,...
Abstract The threat of methicillin-resistant Staphylococcus aureus (MRSA) is increasing worldwide, making it significantly necessary to discover a novel way dealing with related infections. quick spread MRSA isolates among infected individuals has heightened public health concerns and limited treatment options. Vancomycin (VAN) can be applied treat severe infections, the indiscriminate administration this antimicrobial agent caused several in medical settings. Owing advantageous...
Background: The etiology of meningitis, an infection and inflammation the meningeal membranes surrounding brain spinal cord, is multifactorial. Among infectious etiologies are viruses, bacteria, parasites, fungi. Objectives: objective this study to utilize molecular polymerase chain reaction (PCR) method detect bacterial infections causing meningitis in cerebrospinal fluid (CSF) samples from hospitalized patients suspected having meningitis. Subsequently, a comparison made between PCR...
Methicillin-resistant Staphylococcus aureus (MRSA) is recognized as a significant pathogen playing crucial role in causing bacterial infections of skin and soft tissues due to its high capacity for biofilm formation. Niosome-based gel systems offer potential enhancing transdermal drug delivery increasing the effectiveness loaded drugs. The current research investigates feasibility niosomal formulating topical administration teicoplanin (TEC). thin film hydration method was used niosome...
Objectives This study aims to investigate the prevalence and mechanisms of fluoroquinolone resistance in Acinetobacter baumannii strains isolated from hospitals Hamadan, west Iran. It investigates role specific genes mutations contributing this resistance. In addition, effects carbonyl cyanide 3-chlorophenylhydrazone (CCCP) on susceptibility A. fluoroquinolones will be evaluated identify potential strategies combat growing problem. Methods A total 102 isolates were collected various clinical...
Staphylococcus aureus, a prominent bacterial pathogen, presents formidable medical challenges owing to its rapid development of resistance. The emergence multidrug resistant (MDR) S. aureus strains has become pressing concern for healthcare systems, driving researchers explore novel therapeutic strategies managing infections associated with this pathogen. In pursuit, niosomal-based platforms have emerged as promising candidates effectively target and fight conventional antimicrobial Niosomes...
Abstract The Increase in infections caused by resistant strains of Pseudomonas aeruginosa poses a formidable challenge to global healthcare systems. P. is capable causing severe human across diverse anatomical sites, presenting considerable therapeutic obstacles due its heightened drug resistance. Niosomal delivery systems offer enhanced pharmaceutical potential for loaded contents their desirable properties, mainly providing controlled-release profile. This study aimed formulate an...
Background: The rise in multidrug‐resistant pathogens poses a formidable challenge treating hospital‐acquired infections, particularly those caused by Klebsiella pneumoniae . Biofilm formation is critical factor contributing to antibiotic resistance, enhancing bacterial adherence and persistence. K. strains vary virulence factors, influencing their pathogenicity resistance profiles. This study aimed comprehensively analyze patterns, biofilm clinical isolates of from Hamadan hospitals....
The COVID-19 virus is a single-stranded from the Coronaviridae family and has genome of about 29881 bp, which causes acute respiratory disease. One way transmission respiratory, reason for significant mutagenesis in different parts with its mechanisms, including -1 ribosomal frameshifting. Various that have undergone most severe mutations include spike protein, leads to emergence new variants. Most observed are located S protein region known as RBD (Receptor-Binding Domain), binds ACE2...
Background and aims: Increasing the prevalence of nosocomial infections by multidrug resistant (MDR) Pseudomonas aeruginosa has severely challenged choice treatment led to an increased mortality rate. Thus, this study investigated frequency class I II integrons its association with MDR. Materials Methods: A total 175 P. isolates were collected from Shahrekord teaching hospitals Isfahan Shahid Chamran hospital during 12 months (from April 2008 March 2009). Antibiotic susceptibility was...