- Anorectal Disease Treatments and Outcomes
- Pelvic floor disorders treatments
- Colorectal Cancer Surgical Treatments
- Hernia repair and management
- Diverticular Disease and Complications
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Cardiac, Anesthesia and Surgical Outcomes
- Urinary Bladder and Prostate Research
- Cancer survivorship and care
- Congenital gastrointestinal and neural anomalies
- Pelvic and Acetabular Injuries
- Stoma care and complications
- Enhanced Recovery After Surgery
- Medical Malpractice and Liability Issues
- Esophageal and GI Pathology
- Gastrointestinal motility and disorders
- Anesthesia and Pain Management
- Colorectal Cancer Treatments and Studies
- Congenital Diaphragmatic Hernia Studies
- Pressure Ulcer Prevention and Management
- Intestinal and Peritoneal Adhesions
- Childhood Cancer Survivors' Quality of Life
- Patient Safety and Medication Errors
- Minimally Invasive Surgical Techniques
Manchester University NHS Foundation Trust
2018-2025
University of Manchester
2012-2025
Manchester Academic Health Science Centre
2024-2025
Wythenshawe Hospital
2015-2024
Cleveland Clinic
2023
Memorial Sloan Kettering Cancer Center
2019
National Health Service
2018
Castle Hill Hospital
2003-2014
University of Hull
2003-2013
Leeds Teaching Hospitals NHS Trust
2012-2013
An elective defunctioning ileostomy is commonly employed to attenuate the morbidity that may arise from distal anastomotic leakage. The magnitude of risk associated with subsequent closure difficult estimate as many data small series. This study looked at rate complications and predictive factors in a large series patients.The National Surgical Quality Improvement Program database was queried for patients who had an between 2005 2010. Patient demographics, preoperative operative variables...
The aim of this study was to delineate the impact smoking on postoperative outcomes after colorectal resection for malignant and benign processes.Studies date have implicated as a risk factor increased complications. However, there is paucity data effects surgery in particular compared with processes.The American College Surgeon's National Surgical Quality Improvement Program (2005-2010) database queried patients undergoing elective major cancer, diverticular disease, or inflammatory bowel...
Local recurrence after curative excision for rectal cancer is frequently regarded as a failure of surgery. The macroscopic quality the excised mesorectum total mesorectal has been proposed means assessment adequacy This study was designed to determine utility grading in prediction local and overall surgery.All patients undergoing resection primary adenocarcinoma rectum had prospectively applied their specimens, according classification by Quirke et al. (Grades 1-3; 3 best). outcome...
Abstract Objective Transanal endoscopic microsurgery (TEM) is considered to be a safe and effective treatment for selected rectal neoplasms. We demonstrate that in addition the recognized clinical benefits of less invasive TEM approach, there are substantial economic benefits. Method reviewed our prospective database patients undergoing excision lesion between July 1997 December 2003. A cost analysis was undertaken, including procedural related costs compared with relevant open procedures....
Surgical cases that include trainees are associated with worse outcomes in comparison those attending surgeons alone.This study aimed to identify whether resident involvement partial colectomy was when evaluated by surgical approach and experience.This is a retrospective using the National Quality Improvement Program database.This evaluates included database.All patients were who underwent including both open laparoscopic approaches.Residents involved.The primary outcome measures association...
Abstract Background Complications following reversal of Hartmann's procedure are common, with morbidity rates up to 50 per cent, and a mortality rate as high 10 cent. This is based on case series heterogeneous data collection analysis. study determined risk factors for complications reversal. Methods Patients who underwent elective open laparoscopic were identified from the American College Surgeons National Surgical Quality Improvement Program database (2005–2010). The programme collects...
Objectives High-resolution anorectal manometry (HRAM) is the established investigation in faecal incontinence (FI). However, provocative tests (functional lumen imaging probe (FLIP) and anal acoustic reflectometry (AAR)) have been proposed as alternatives. This study uniquely explores all three methods correlation with FI symptoms subtypes. Methods was a prospective observational of patients attending tertiary pelvic floor unit between August 2022 January 2024. Patients underwent HRAM, FLIP...
<title>Abstract</title> Personality prediction from CVs using advanced NLP is quite a significant area of interest in contemporary human resource management and recruitment processes. The study generates an innovative approach to making predictions, with textual data extracted sent for analysis regarding the Big-5 personality traits person. We devise rather powerful framework quantitatively extract subtle cues unstructured text techniques, particular transformer-based models incorporation...
Studies have shown an association between baseline quality of life (Qol) and survival in advanced cancers. The aim this study was to investigate their predictive value long term after elective colorectal cancer resection.A consecutive series patients undergoing surgery for nonmetastatic disease were recruited 2003/04. Patients completed standardized questionnaires (HADS, FACTC, MRS, PANAS) prior 6 weeks surgery. Univariate (log-rank test) multivariate analyses (Cox proportional hazards)...
BACKGROUND: Abdominoperineal excision of rectum has been associated with poor oncological specimens and high local recurrence rates in comparison restorative surgery. The role recent changes operative position yet to be evaluated. OBJECTIVES: This study aimed determine whether a change the perineal phase from Lloyd-Davies prone jackknife might improve margins outcomes. METHODS: A single-institution review prospectively maintained database comparing quality outcomes after abdominoperineal...
Introduction Faecal incontinence (FI) is a common condition with significant impact on quality of life (QoL). Neuromodulation treatments delivered by members the multidisciplinary team including sacral nerve stimulation (SNS) and percutaneous tibial (PTNS) are options for FI refractory to conservative management. The aim this study was assess whether successful treatment one neuromodulation modality corresponds success in other. Methods A retrospective review prospectively managed database...
Vascular endothelial growth factor (VEGF) and psychosocial factors have both been shown to independent prognostic value in colorectal cancer. Recently, an association between VEGF has reported patients with ovarian cancer.A consecutive series of eligible undergoing elective resection for cancer were invited participate. Standardized measures various aspects quality life (QoL) administered 5-12 days before surgery, again 6-8 weeks after the operation, blood samples obtained at same times....