Fergal J. Fleming

ORCID: 0000-0003-0553-1591
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About
Contact & Profiles
Research Areas
  • Colorectal Cancer Surgical Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Colorectal Cancer Screening and Detection
  • Colorectal and Anal Carcinomas
  • Hernia repair and management
  • Gastric Cancer Management and Outcomes
  • Diverticular Disease and Complications
  • Colorectal Cancer Treatments and Studies
  • Appendicitis Diagnosis and Management
  • Enhanced Recovery After Surgery
  • Pelvic and Acetabular Injuries
  • Anorectal Disease Treatments and Outcomes
  • Aortic aneurysm repair treatments
  • Venous Thromboembolism Diagnosis and Management
  • Esophageal and GI Pathology
  • Nutrition and Health in Aging
  • Intestinal and Peritoneal Adhesions
  • Genetic factors in colorectal cancer
  • Abdominal Surgery and Complications
  • Frailty in Older Adults
  • Clinical practice guidelines implementation
  • Stoma care and complications
  • Surgical Simulation and Training
  • Blood transfusion and management
  • Breast Cancer Treatment Studies

University of Rochester Medical Center
2016-2025

Twitter (United States)
2022-2024

Royal Alexandra Hospital
2024

University of Rochester
2010-2023

University of Southampton
2023

Southampton General Hospital
2004-2023

St. Vincent's University Hospital
2002-2022

Collaborative Group (United States)
2022

University Hospitals of Cleveland
2017

American Society of Colon and Rectal Surgeons
2013-2017

The impact of intraoperative erythrocyte transfusion on outcomes anemic patients undergoing noncardiac surgery has not been well characterized. objective this study was to examine the association between blood and mortality morbidity in with severe anemia (hematocrit less than 30%) who are exposed one or two units erythrocytes intraoperatively.This a retrospective analysis 30-day 10,100 general, vascular, orthopedic surgery. We estimated separate multivariate logistic regression models for...

10.1097/aln.0b013e3182054d06 article EN Anesthesiology 2011-01-15

Background Previous studies have demonstrated that obesity is paradoxically associated with a lower risk of mortality after noncardiac surgery. This study will determine the impact modified metabolic syndrome (defined as presence obesity, hypertension, and diabetes) on perioperative outcomes. Methods based data from 310,208 patients in American College Surgeons National Surgical Quality Improvement Program database. We estimated separate multivariate logistic regression models for 30-day...

10.1097/aln.0b013e3181eff32e article EN Anesthesiology 2010-08-31

To identify predictors of positive circumferential resection margin following rectal cancer in the United States.Positive is associated with a high rate local recurrence and poor morbidity mortality for patients. Prior study has shown compliance national guidelines, but whether this finding reflected patient outcomes yet to be shown.Patients who underwent stage I-III were identified from 2010-2011 National Cancer Database. The primary outcome was margin. relationship between patient,...

10.1097/sla.0000000000001391 article EN Annals of Surgery 2015-10-16

An elective defunctioning ileostomy is commonly employed to attenuate the morbidity that may arise from distal anastomotic leakage. The magnitude of risk associated with subsequent closure difficult estimate as many data small series. This study looked at rate complications and predictive factors in a large series patients.The National Surgical Quality Improvement Program database was queried for patients who had an between 2005 2010. Patient demographics, preoperative operative variables...

10.1111/codi.12029 article EN Colorectal Disease 2012-09-13

The aim of this study was to delineate the impact smoking on postoperative outcomes after colorectal resection for malignant and benign processes.Studies date have implicated as a risk factor increased complications. However, there is paucity data effects surgery in particular compared with processes.The American College Surgeon's National Surgical Quality Improvement Program (2005-2010) database queried patients undergoing elective major cancer, diverticular disease, or inflammatory bowel...

10.1097/sla.0b013e3182708cc5 article EN Annals of Surgery 2012-10-11

The American Society of Colon and Rectal Surgeons is dedicated to ensuring high-quality patient care by advancing the science, prevention, management disorders diseases colon, rectum, anus. Clinical Practice Guidelines Committee composed society members who are chosen because they have demonstrated expertise in specialty colon rectal surgery. This committee was created lead international efforts defining quality for conditions related accompanied development clinical practice guidelines...

10.1097/dcr.0000000000000982 article EN Diseases of the Colon & Rectum 2017-12-07

Given scarce data regarding the relationship among age, complications, and survival beyond 30-day postoperative period for oncology patients in United States, this study identified age-related differences complications rate cause of 1-year mortality following colon cancer surgery. The NY State Cancer Registry Statewide Planning Research Cooperative System stage I–III resections (2004–2011). Multivariable logistic regression analyses assessed age (<65, 65–74, ⩾75), survival, death. Among 24...

10.1038/bjc.2016.421 article EN cc-by-nc-sa British Journal of Cancer 2017-01-01

BACKGROUND: Twenty-nine percent of postileostomy discharges are readmitted, most commonly because dehydration. However, there is a lack detailed data specifically evaluating factors associated with readmission In addition, patients history an ileostomy have often been excluded from previous studies and therefore represent group understudied ileostomates. OBJECTIVE: This study aimed to evaluate available at discharge 30-day for dehydration, rather than all-cause readmissions. DESIGN: was...

10.1097/dcr.0000000000001137 article EN Diseases of the Colon & Rectum 2018-10-04
Charles S. Parsons Nathan I. Shapiro Randall Cooper Aleksandr Tichter Arden M. Morris and 95 more Bruce Wolfe Donald M. Yealy Karla V. Ballman Kathleen O’Connor Olga Owens Thomas Diflo Alyssa Hayward Lillian Adrianna Hayes Joe H. Patton Hikmatullah Arif Laura Hennessey Erika M. Wolff Farhood Farjah Kelsey Pullar Brett Faine Cathy Fairfield Dionne A. Skeete Debbie Lew Karla Bernardi Naila Dhanani Oscar Olavarria Stephanie Marquez Tien C. Ko Vance Y. Sohn Alan E. Jones Deepti Patki Matthew Kutcher Rebekah K. Peacock Bruce Chung Damien Carter David MacKenzie Debra Burris Joseph Mack Terilee Gerry Emily E. Anderson Darrell A. Campbell Fergal J. Fleming David B. Hoyt J.J. Tepas Richard Whitten SreyRam Kuy Daniel Lessler Jason Maggi Kristyn Pierce Marcovalerio Melis Mohamad Abouzeid Paresh Shah Prashant Sinha William Chiang Amy P. Rushing Steven Steinberg Elliott Skopin Heather VanDusen Kimberly Deeney Mary Guiden Meridith Weiss Miriam Hernandez Brandon Tudor Careen Foster Shaina Schaetzel Dayna Morgan John Tschirhart Julie Wallick Katherine Mandell Ryan Martinez Sean Wells Brant Putnam Dennis Kim Erin C. Howell Lara H. Spence Ross J. Fleischman Darin J. Saltzman Debbie Mireles Formosa Chen Gregory J. Moran Kavitha Pathmarajah Lisandra Uribe Paul J. Schmit Robert S. Bennion Cindy Hsu Krishnan Raghavendran Nathan Haas Norman Olbrich Pauline Park Amber K. Sabbatini Daniel Kim Estel Williams Karen Horvath Zoe Parr Karen F. Miller Kelly M. Moser Abigail Wiebusch Julianna Yu Scott Osborn Billie Johnsson

Use of antibiotics for the treatment appendicitis is safe and has been found to be noninferior appendectomy based on self-reported health status at 30 days. Identifying patient characteristics associated with a greater likelihood within days in those who initiate could support more individualized decision-making.To assess factors undergoing initiating appendicitis.In this cohort study using data from Comparison Outcomes Antibiotic Drugs Appendectomy (CODA) randomized clinical trial, among...

10.1001/jamasurg.2021.6900 article EN JAMA Surgery 2022-01-12

In human breast cancer, the growth factor receptor HER2 is associated with disease progression and resistance to endocrine treatment. Growth induced mitogen activated protein kinase activity can phosphorylate not only oestrogen receptor, but also its coactivator proteins AIB1 SRC-1.To determine whether insensitivity treatment in positive patients enhanced expression of proteins, transcriptional regulator, PEA3, coregulatory SRC-1, was assessed a cohort cancer known status.PEA3, AIB1, SRC-1...

10.1136/jcp.2004.016733 article EN Journal of Clinical Pathology 2004-09-27

Studies to date examining the impact of laparoscopy in IPAA have failed demonstrate a significant, consistent benefit terms reduction short-term morbidity or length stay.The aim this study was establish operative approach (laparoscopic open) on outcomes after formation.With use American College Surgeons National Surgical Quality Improvement Program participant file (2005-2008), records patients who underwent open laparoscopic with diverting ileostomy were examined.Risk-adjusted 30-day and...

10.1007/dcr.0b013e3181fb4232 article EN Diseases of the Colon & Rectum 2011-02-01

Studies to date examining the impact of laparoscopy in resection for Crohn's disease on short-term morbidity have been limited by small study populations. The aim this was establish operative approach (laparoscopic or open) outcomes after ileocolic disease.Ileocolic resections were identified using Current Procedural Terminology (CPT) and International Classification Disease, Ninth Revision, Clinical Modification (ICD-9-CM) codes from National Surgical Quality Improvement Program (NSQIP)...

10.1111/j.1463-1318.2011.02756.x article EN Colorectal Disease 2011-08-10

High BMI is often used as a proxy for obesity and has been considered risk factor the development of an incisional hernia after abdominal surgery. However, does not accurately reflect fat distribution.The purpose this work was to investigate relationship among different measurements hernia.This retrospective cohort study.The study included single academic institution in New York from 2003 2010.The consists 193 patients who underwent colorectal cancer resection.Preoperative CT scans were...

10.1097/dcr.0000000000000261 article EN Diseases of the Colon & Rectum 2015-01-13

National Comprehensive Cancer Network treatment guidelines for patients with locally advanced rectal cancer include neoadjuvant chemoradiation followed by total mesorectal excision and adjuvant chemotherapy. The objective of the current study was to examine rate chemotherapy associated survival in stage II/III cancer.The 2006 2011 Data Base queried AJCC clinical who underwent surgical resection. A mixed effects multivariable logistic regression identified factors receipt Cox proportional...

10.1002/cncr.30261 article EN Cancer 2016-08-25
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