- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Screening and Detection
- Colorectal and Anal Carcinomas
- Hernia repair and management
- Gastric Cancer Management and Outcomes
- Diverticular Disease and Complications
- Colorectal Cancer Treatments and Studies
- Appendicitis Diagnosis and Management
- Enhanced Recovery After Surgery
- Pelvic and Acetabular Injuries
- Anorectal Disease Treatments and Outcomes
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Esophageal and GI Pathology
- Nutrition and Health in Aging
- Intestinal and Peritoneal Adhesions
- Genetic factors in colorectal cancer
- Abdominal Surgery and Complications
- Frailty in Older Adults
- Clinical practice guidelines implementation
- Stoma care and complications
- Surgical Simulation and Training
- Blood transfusion and management
- Breast Cancer Treatment Studies
University of Rochester Medical Center
2016-2025
Twitter (United States)
2022-2024
Royal Alexandra Hospital
2024
University of Rochester
2010-2023
University of Southampton
2023
Southampton General Hospital
2004-2023
St. Vincent's University Hospital
2002-2022
Collaborative Group (United States)
2022
University Hospitals of Cleveland
2017
American Society of Colon and Rectal Surgeons
2013-2017
The impact of intraoperative erythrocyte transfusion on outcomes anemic patients undergoing noncardiac surgery has not been well characterized. objective this study was to examine the association between blood and mortality morbidity in with severe anemia (hematocrit less than 30%) who are exposed one or two units erythrocytes intraoperatively.This a retrospective analysis 30-day 10,100 general, vascular, orthopedic surgery. We estimated separate multivariate logistic regression models for...
Background Previous studies have demonstrated that obesity is paradoxically associated with a lower risk of mortality after noncardiac surgery. This study will determine the impact modified metabolic syndrome (defined as presence obesity, hypertension, and diabetes) on perioperative outcomes. Methods based data from 310,208 patients in American College Surgeons National Surgical Quality Improvement Program database. We estimated separate multivariate logistic regression models for 30-day...
To identify predictors of positive circumferential resection margin following rectal cancer in the United States.Positive is associated with a high rate local recurrence and poor morbidity mortality for patients. Prior study has shown compliance national guidelines, but whether this finding reflected patient outcomes yet to be shown.Patients who underwent stage I-III were identified from 2010-2011 National Cancer Database. The primary outcome was margin. relationship between patient,...
An elective defunctioning ileostomy is commonly employed to attenuate the morbidity that may arise from distal anastomotic leakage. The magnitude of risk associated with subsequent closure difficult estimate as many data small series. This study looked at rate complications and predictive factors in a large series patients.The National Surgical Quality Improvement Program database was queried for patients who had an between 2005 2010. Patient demographics, preoperative operative variables...
The aim of this study was to delineate the impact smoking on postoperative outcomes after colorectal resection for malignant and benign processes.Studies date have implicated as a risk factor increased complications. However, there is paucity data effects surgery in particular compared with processes.The American College Surgeon's National Surgical Quality Improvement Program (2005-2010) database queried patients undergoing elective major cancer, diverticular disease, or inflammatory bowel...
The American Society of Colon and Rectal Surgeons is dedicated to ensuring high-quality patient care by advancing the science, prevention, management disorders diseases colon, rectum, anus. Clinical Practice Guidelines Committee composed society members who are chosen because they have demonstrated expertise in specialty colon rectal surgery. This committee was created lead international efforts defining quality for conditions related accompanied development clinical practice guidelines...
Given scarce data regarding the relationship among age, complications, and survival beyond 30-day postoperative period for oncology patients in United States, this study identified age-related differences complications rate cause of 1-year mortality following colon cancer surgery. The NY State Cancer Registry Statewide Planning Research Cooperative System stage I–III resections (2004–2011). Multivariable logistic regression analyses assessed age (<65, 65–74, ⩾75), survival, death. Among 24...
BACKGROUND: Twenty-nine percent of postileostomy discharges are readmitted, most commonly because dehydration. However, there is a lack detailed data specifically evaluating factors associated with readmission In addition, patients history an ileostomy have often been excluded from previous studies and therefore represent group understudied ileostomates. OBJECTIVE: This study aimed to evaluate available at discharge 30-day for dehydration, rather than all-cause readmissions. DESIGN: was...
Use of antibiotics for the treatment appendicitis is safe and has been found to be noninferior appendectomy based on self-reported health status at 30 days. Identifying patient characteristics associated with a greater likelihood within days in those who initiate could support more individualized decision-making.To assess factors undergoing initiating appendicitis.In this cohort study using data from Comparison Outcomes Antibiotic Drugs Appendectomy (CODA) randomized clinical trial, among...
In human breast cancer, the growth factor receptor HER2 is associated with disease progression and resistance to endocrine treatment. Growth induced mitogen activated protein kinase activity can phosphorylate not only oestrogen receptor, but also its coactivator proteins AIB1 SRC-1.To determine whether insensitivity treatment in positive patients enhanced expression of proteins, transcriptional regulator, PEA3, coregulatory SRC-1, was assessed a cohort cancer known status.PEA3, AIB1, SRC-1...
Studies to date examining the impact of laparoscopy in IPAA have failed demonstrate a significant, consistent benefit terms reduction short-term morbidity or length stay.The aim this study was establish operative approach (laparoscopic open) on outcomes after formation.With use American College Surgeons National Surgical Quality Improvement Program participant file (2005-2008), records patients who underwent open laparoscopic with diverting ileostomy were examined.Risk-adjusted 30-day and...
Studies to date examining the impact of laparoscopy in resection for Crohn's disease on short-term morbidity have been limited by small study populations. The aim this was establish operative approach (laparoscopic or open) outcomes after ileocolic disease.Ileocolic resections were identified using Current Procedural Terminology (CPT) and International Classification Disease, Ninth Revision, Clinical Modification (ICD-9-CM) codes from National Surgical Quality Improvement Program (NSQIP)...
High BMI is often used as a proxy for obesity and has been considered risk factor the development of an incisional hernia after abdominal surgery. However, does not accurately reflect fat distribution.The purpose this work was to investigate relationship among different measurements hernia.This retrospective cohort study.The study included single academic institution in New York from 2003 2010.The consists 193 patients who underwent colorectal cancer resection.Preoperative CT scans were...
National Comprehensive Cancer Network treatment guidelines for patients with locally advanced rectal cancer include neoadjuvant chemoradiation followed by total mesorectal excision and adjuvant chemotherapy. The objective of the current study was to examine rate chemotherapy associated survival in stage II/III cancer.The 2006 2011 Data Base queried AJCC clinical who underwent surgical resection. A mixed effects multivariable logistic regression identified factors receipt Cox proportional...