A5048601724- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Advanced MRI Techniques and Applications
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Long-Term Effects of COVID-19
- Transcranial Magnetic Stimulation Studies
- Radiomics and Machine Learning in Medical Imaging
- Parkinson's Disease Mechanisms and Treatments
- MRI in cancer diagnosis
- COVID-19 and Mental Health
- Intensive Care Unit Cognitive Disorders
- Neurological disorders and treatments
- Neurological Disease Mechanisms and Treatments
- EEG and Brain-Computer Interfaces
- Traumatic Brain Injury Research
- Medical Imaging Techniques and Applications
- Brain Tumor Detection and Classification
- Health, Environment, Cognitive Aging
- Traumatic Brain Injury and Neurovascular Disturbances
- Neuroinflammation and Neurodegeneration Mechanisms
- Face and Expression Recognition
- Neurobiology of Language and Bilingualism
Universitat de Barcelona
2015-2025
Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine
2020-2025
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2011-2025
Institut d'Investigacions Biomèdiques de Barcelona
2015-2024
Fundació Clínic per a la Recerca Biomèdica
2024
Biomedical Research Networking Center on Neurodegenerative Diseases
2022
Hospital Clínic de Barcelona
2010-2020
University of Oslo
2015-2020
Institut Guttmann
2012
École Normale Supérieure - PSL
2008
The purpose of this work was to evaluate changes in the connectivity patterns a set cognitively relevant, dynamically interrelated brain networks association with cognitive deficits Parkinson's disease (PD) using resting-state functional MRI.Sixty-five nondemented PD patients and 36 matched healthy controls were included.Thirty-four percent classified as having mild impairment (MCI) based on performance attention/executive, visuospatial/visuoperceptual (VS/VP) memory functions.A data-driven...
Significance Here we show that developmental and adult aging-related changes in cortical thickness follow closely the genetic organization of cerebral cortex. A total 1,633 MRI scans from 974 participants 4.1 to 88.5 y age were used measure longitudinal thickness, topographic pattern change was compared with relationship between subdivisions maximal shared influence, obtained an independent sample 406 middle-aged twins. Cortical due maturation adhered cortex, indicating individual...
Abstract Graph‐theoretical analyses of functional networks obtained with resting‐state magnetic resonance imaging (fMRI) have recently proven to be a useful approach for the study substrates underlying cognitive deficits in different diseases. We used this technique investigate whether Parkinson's disease (PD) are associated changes global and local network measures. Thirty‐six healthy controls (HC) 66 PD patients matched age, sex, education were classified as having mild impairment (MCI) or...
Abstract Objective To identify CT-acquisition parameters accounting for radiomics variability and to develop a post-acquisition CT-image correction method reduce improve classification in both phantom clinical applications. Methods protocols were prospectively tested phantom. The multi-centric retrospective study included CT scans of patients with colorectal/renal cancer liver metastases. Ninety-three features first order texture extracted. Intraclass correlation coefficients (ICCs) between...
Obesity is a major health problem in modern societies. It has been related to abnormal functional organization of brain networks believed process homeostatic (internal) and/or salience (external) information. This study used resting‐state magnetic resonance imaging analysis delineate possible changes obesity. A group 18 healthy adult participants with obesity were compared 16 lean while performing task, the data being evaluated by independent component analysis. Participants also completed...
The study of brain activity and connectivity at rest provides a unique opportunity for the investigation substrates cognitive outcome after traumatic axonal injury. This knowledge may contribute to improve clinical management rehabilitation programs.To functional magnetic resonance imaging abnormalities in signal amplitude their relationship patients with chronic severe injury.Observational study.University Barcelona Hospital Clinic de Barcelona, Institut Guttmann-Neurorehabilitation...
Neuroimaging studies of familial Alzheimer's disease allow investigation the process before clinical onset. We performed semi-automated MRI analysis to evaluate cortical thickness (CTh), grey matter (GM) volumes, and GM diffusivity indexes
One of the most prevalent symptoms post-COVID condition is cognitive impairment, which results in a significant degree disability and low quality life. In studies with large sample sizes, attention, memory, executive function were reported as long-term symptoms. This study aims to describe dysfunction individuals, compare objective neuropsychological performance those individuals without complaints, identify short exams that can differentiate from controls. To address these aims, Nautilus...
Patients with post-coronavirus disease 2019 (COVID-19) conditions typically experience cognitive problems. Some studies have linked COVID-19 severity long-term damage, while others did not observe such associations. This discrepancy can be attributed to methodological and sample variations. We aimed clarify the relationship between outcomes determine whether initial symptomatology predict Cognitive evaluations were performed on 109 healthy controls 319 post-COVID individuals categorized into...
<h3>Objective:</h3> This study explores the functional and structural patterns of connectivity underlying working memory impairment after severe traumatic axonal injury. <h3>Methods:</h3> We performed an fMRI n-back task acquired diffusion tensor images (DTI) in a group 19 chronic-stage patients with brain injury (TBI) evidence matched healthy controls. image analyses FSL software data were analyzed using probabilistic independent component analysis. Fractional anisotropy (FA) maps from DTI...
There is evidence longitudinal atrophy in posterior brain areas early-onset Alzheimer's disease (EOAD; aged<65years), but no studies have been conducted an EOAD cohort with fluid biomarkers characterization. We used 3T-MRI and Freesurfer 6.0 to investigate cortical subcortical gray matter loss at two years 12 patients (A+T+N+) compared 19 controls (A-T-N-) from the Hospital Clínic Barcelona cohort. explored group differences patterns we correlated baseline CSF-biomarkers levels EOAD....