A5051058058- Ovarian function and disorders
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Hypothalamic control of reproductive hormones
- Reproductive Health and Technologies
- Gestational Diabetes Research and Management
- Diabetes Treatment and Management
- Hormonal and reproductive studies
- Growth Hormone and Insulin-like Growth Factors
- Posttraumatic Stress Disorder Research
- Estrogen and related hormone effects
- Bariatric Surgery and Outcomes
- Diabetes Management and Research
- Fatty Acid Research and Health
- Maternal Mental Health During Pregnancy and Postpartum
- Oral microbiology and periodontitis research
- Birth, Development, and Health
- Menopause: Health Impacts and Treatments
- Phytoestrogen effects and research
- Prenatal Screening and Diagnostics
- Metabolism, Diabetes, and Cancer
- Pregnancy and preeclampsia studies
- Stress Responses and Cortisol
- Resilience and Mental Health
- Hearing, Cochlea, Tinnitus, Genetics
Baton Rouge Clinic
2024
Woman's Hospital
2011-2022
Reproductive Medicine Associates of New Jersey
2003-2008
Weatherford College
2008
Reproductive Medicine Associates of New York
2007-2008
Tulane University
1981-2008
Pennington Biomedical Research Center
2007
University of Pennsylvania
2005-2006
Philadelphia University
2006
Emory University
2005
ObjectiveTo study the efficacy and safety of GLP-1 analog liraglutide 3 mg (LIRA mg) vs. placebo (PL) for reduction body weight (BW) hyperandrogenism in women with obesity polycystic ovary syndrome (PCOS).DesignRandomized, double-blind, placebo-controlled trial.SettingHospital-based outpatient endocrine metabolic center.Patient(s)Women diagnosed PCOS (NIH criteria) were randomly assigned to LIRA (n = 55) or PL 27) once daily 32 weeks lifestyle intervention.Intervention(s)Study visits at...
Abstract Context: Insulin resistance and obesity are common features of the polycystic ovary syndrome (PCOS). Weight loss use insulin-lowering drugs have been shown to improve both reproductive metabolic aspects PCOS. Objective: We evaluated exenatide (EX) metformin (MET), alone in combination (COM), on menstrual cyclicity, hormonal parameters, profiles, inflammatory markers overweight, insulin-resistant women with Design, Setting, Participants: Sixty overweight oligoovulatory PCOS (body...
To determine whether male age influences embryo development and reproductive potential in assisted technology cycles.Retrospective cohort analysis.Private IVF center.One thousand twenty-three partners participating anonymous oocyte donation cycles.Infertile couples undergoing 1,023 cycles.Live birth rate.A significant increase pregnancy loss, decrease live rate, blastocyst formation rate were noted men >50 years of age. There was no difference implantation or early through the cleavage stage...
Two-thirds of pregnant women exceed gestational weight gain (GWG) recommendations. Because excess GWG is associated with adverse outcomes for mother and child, development scalable cost-effective approaches to deliver intensive lifestyle programs during pregnancy urgent.The aim this study was decrease the proportion who Institute Medicine (IOM) 2009 guidelines.In a parallel-arm randomized controlled trial, 54 (age 18-40 years) were overweight (n=25) or obese (n=29) enrolled test whether an...
Abstract Context Glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors reduce weight improve insulin sensitivity via different mechanisms. Objective The efficacy of once-weekly exenatide (EQW) dapagliflozin (DAPA) alone coadministered (EQW/DAPA), DAPA/extended-release (ER) metformin (DAPA/MET), phentermine topiramate extended release (PHEN/TPM) on metabolic parameters, body composition, sex hormones were examined in obese women with PCOS. Methods Nondiabetic...
Objective: To determine the effect of estrogen replacement therapy (ERT) on serum androgen levels in postmenopausal women. Methods: We measured dehydroepiandrosterone (DHEA), DHEA-sulfate, testosterone, estradiol (E2), LH, FSH, and sex hormone binding globulin 8:00 am fasting samples from a previous randomized, blinded, placebo-controlled crossover study which 28 women (27 naturally menopausal) were given 2 mg/day oral micronized estradiol. The treatment arms 12 weeks with 6-week washout....
Accessible summary • Multiple experiences of disaster are associated with worse mental health. On the other hand, some women who exposed to multiple disasters have better health after second than first. Women low social support and high levels daily hassles less likely be resilient when a later disaster. Few studies assessed results exposures Our objective was examine effect experiencing Hurricane Gustav on previously Katrina. A total 102 from Southern Louisiana were interviewed by...
Few studies have specifically examined the relationship between periodontal disease and gestational diabetes mellitus (GDM). The objective of this study was to examine whether maternal is associated with GDM.A case-control conducted 53 pregnant women GDM 106 without at Woman's Hospital, Baton Rouge, Louisiana. examinations were performed by a calibrated dentist who masked diabetic status women. Periodontitis defined as presence any site probing depth (PD) >or=4 mm or clinical attachment loss...
Natural disaster is often a cause of psychopathology, and women are vulnerable to post-traumatic stress disorder (PTSD) depression. Depression also common after woman gives birth. However, no research has addressed postpartum women's mental health natural disaster. Interviews were conducted in 2006–2007 with who had been pregnant during or shortly Hurricane Katrina. 292 New Orleans Baton Rouge interviewed at delivery 2 months postpartum. was assessed using the Edinburgh Scale PTSD...
Background: After a natural disaster, mental disorders often become long-term public health concern. Previous studies under smaller-scale disaster conditions suggest loss of psychosocial resources is associated with psychological distress. Methods: We examined the occurrence depression 6 and 12 months postpartum among 208 women residing in New Orleans Baton Rouge, Louisiana, who were pregnant during or immediately after Hurricane Katrina's landfall. Based on Conservation Resources (COR)...
The aim was to investigate the impact of polycystic ovary syndrome (PCOS) on regulation lipolysis by catecholamine and for first time atrial natriuretic peptide (ANP) before after 16 wk aerobic training.Eight hyperandrogenic obese women with PCOS [age, 25 +/- 1 yr; body mass index (BMI), 32.0 1.6 kg/m(2)] seven healthy BMI-matched controls participated. Studies were performed a 16-wk exercise training program in cross-sectionally group controls.Lipolysis measured vitro isolated adipocytes...
In this study, we report the effects of cyclic hormone replacement therapy on carbohydrate metabolism in six women with premature ovarian failure. Using tolbutamide-modified iv glucose tolerance tests patients were evaluated during three different intervals their second treatment cycle: no replacement, estradiol-only (E2-only) and E2-plus-medroxyprogesterone acetate (MPA) replacement. Insulin sensitivity effectiveness derived using insulin levels obtained from analyzed minimal model computer...
A specific and sensitive RIA was developed for measuring immunoreactive LHRH (IR-LHRH) in methanol acid-extracted human plasma. Heparinized blood samples were obtained from normal adult women men, the plasma extracted with methanol, acidified, lyophilized, stored at -20 C until assayed LHRH. The lowest detectable levels of IR-LHRH 1.0-3.5 ml ranged 0.975-1.95 pg/assay tube, recovery synthetic averaged 88.6 +/- 2.4% (SE). Gel chromatographic separation analysis revealed comparable elution...
Objective: Little is known about the effects of disaster exposure and intensity on development mental disorders among pregnant women. The aim this study was to examine effect Hurricane Katrina health in women.Design: Prospective cohort epidemiological study.Setting: Tertiary hospitals New Orleans Baton Rouge, USA.Participants: Women who were during or became immediately after hurricane.Main outcome measures: Post-traumatic stress disorder (PTSD) depression.Results: frequency PTSD higher...