A5000973684- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Ovarian function and disorders
- Reproductive Health and Technologies
- Genomic variations and chromosomal abnormalities
- Sperm and Testicular Function
- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Molecular Biology Techniques and Applications
- Animal Genetics and Reproduction
- Genetic Syndromes and Imprinting
- Demographic Trends and Gender Preferences
- Irish and British Studies
- Acute Ischemic Stroke Management
- CRISPR and Genetic Engineering
- Gynecological conditions and treatments
- Pluripotent Stem Cells Research
- Artificial Intelligence in Healthcare and Education
- Cancer Genomics and Diagnostics
- Reproductive Health and Contraception
- Chromosomal and Genetic Variations
- Gene expression and cancer classification
- Mechanical Circulatory Support Devices
- Law, AI, and Intellectual Property
Our Lady of Lourdes Medical Center
2022-2024
Reproductive Biology Associates
2015-2023
New Hope Fertility Center
2023
Virtua Health
2022-2023
Florida Urology Associates
2022
Texas Children's Hospital
2016
Reproductive Medicine Associates of New Jersey
2000-2009
Johnson University
2007-2009
Reproductive Medicine Associates of New York
2003-2008
Weatherford College
2008
Identifying the genes responsible for human diseases requires combining information about gene position with clues biological function. The recent availability of whole-genome data sets RNA and protein expression provides powerful new sources functional insight. Here we illustrate how such can expedite disease-gene discovery, by using them to identify causing Leigh syndrome, French-Canadian type (LSFC, Online Mendelian Inheritance in Man no. 220111), a cytochrome c oxidase deficiency that...
To determine whether male age influences embryo development and reproductive potential in assisted technology cycles.Retrospective cohort analysis.Private IVF center.One thousand twenty-three partners participating anonymous oocyte donation cycles.Infertile couples undergoing 1,023 cycles.Live birth rate.A significant increase pregnancy loss, decrease live rate, blastocyst formation rate were noted men >50 years of age. There was no difference implantation or early through the cleavage stage...
ObjectiveTo perform a series of analyses characterizing an artificial intelligence (AI) model for ranking blastocyst-stage embryos. The primary objective was to evaluate the benefit predicting clinical pregnancy, whereas secondary identify limitations that may impact use.DesignRetrospective study.SettingConsortium 11 assisted reproductive technology centers in United States.Patient(s)Static images 5,923 transferred blastocysts and 2,614 nontransferred aneuploid...
Preimplantation genetic testing commonly employs simplistic copy-number analyses to screen for aneuploidy in blastocyst trophectoderm biopsies. Interpreting intermediate copy number alone as evidence of mosaicism has led suboptimal estimation its prevalence. Because originates from mitotic nondisjunction, utilizing SNP microarray technology identify the cell-division origins might provide a more accurate The present study develops and validates method determining origin human by using both...
Assessing fertilized human embryos is crucial for in vitro fertilization, a task being revolutionized by artificial intelligence. Existing models used embryo quality assessment and ploidy detection could be significantly improved effectively utilizing time-lapse imaging to identify critical developmental time points maximizing prediction accuracy. Addressing this, we develop compare various status across distinct development stages. We present BELA, state-of-the-art model that surpasses...
The COVID-19 pandemic has posed unique concerns and potential risks to women now pregnant or considering childbearing. Although no professional societies have issued recommendations that avoid conception at this time, several organizations recommended a moratorium on infertility services including both medically assisted reproduction reproductive technology shortly after the World Health Organization declared infection be pandemic. Reasons cited for undertaking these extraordinary measures...
Differential CYP1A1 inducibility, reflecting variations in aromatic hydrocarbon receptor (AHR) affinity among inbred mouse strains, is an important determinant of environmental toxicity. We took advantage the Ahr polymorphism C57BL/6 and DBA/2 mice to develop oligonucleotide-hybridization screening approach for rapid identification DNA sequence differences between alleles. Oligonucleotides containing single-base changes at polymorphic sites were immobilized on a solid support hybridized with...
Abstract Assessing fertilized human embryos is crucial for in vitro-fertilization (IVF), a task being revolutionized by artificial intelligence and deep learning. Existing models used embryo quality assessment chromosomal abnormality (ploidy) detection could be significantly improved effectively utilizing time-lapse imaging to identify critical developmental time points maximizing prediction accuracy. Addressing this, we developed compared various ploidy status across distinct development...