A5029803966- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Heavy Metal Exposure and Toxicity
- COVID-19 and Mental Health
- Arsenic contamination and mitigation
- Virology and Viral Diseases
- SARS-CoV-2 detection and testing
- Body Contouring and Surgery
- Therapeutic Uses of Natural Elements
- Health, Environment, Cognitive Aging
- COVID-19 and healthcare impacts
- Healthcare Systems and Reforms
- Public Health and Environmental Issues
- COVID-19 Impact on Reproduction
- Dye analysis and toxicity
- Maternal Mental Health During Pregnancy and Postpartum
- Influenza Virus Research Studies
- Environmental Justice and Health Disparities
- Bacterial Infections and Vaccines
- Attention Deficit Hyperactivity Disorder
- Pregnancy and Medication Impact
- Heavy metals in environment
- Environmental and Social Impact Assessments
Universidad del Desarrollo
2020-2025
Clínica Alemana
2022-2025
San Sebastián University
2025
Instituto de Salud Pública de Chile
2024
Universidad del Desarrollo del Estado de Puebla
2021
University of Chile
2018-2020
Ministry of Health
2015
Arsenic chronic exposure, particularly in its inorganic form, represents a significant public health concern. This study was conducted Arica, the northernmost city country, whose inhabitants have been exposed to arsenic both naturally through drinking water and anthropogenically due toxic waste disposal site. We explored changes levels cohort of pregnant women their children over decade, identifying exposure trends determinants. used data on maternal urine samples during pregnancy, collected...
Abstract Background Seroprevalence studies provide an accurate measure of SARS-CoV-2 spread and the presence asymptomatic cases. They also information on uneven impact pandemic, pointing out vulnerable groups to prioritize which is particularly relevant in unequal societies. However, due their high cost, they limited evidence spatial pandemic specially Our objective was estimate prevalence antibodies Chile model its risk distribution. Methods During Oct–Nov 2020, we conducted a...
Chile has achieved the highest coverage for vaccines against SARS-CoV-2 virus worldwide.
Introduction: The association of total arsenic exposure with impaired glucose tolerance and gestational diabetes has been shown; however, evidence regarding urinary inorganic in pregnant women is still limited. Our aim was to evaluate the between concentration among living Arica, Chile. Methods: Cross-sectional study receiving care at primary health centers urban Arica. concentration, while outcome. evaluated using multiple logistic regression models adjusted by age, education level,...
The metabolic response to a maximal exercise test in physically inactive adults remains poorly understood, particularly regarding the role of adiponectin, an adipokine with insulin-sensitizing and anti-inflammatory properties. Adiponectin circulates three isoforms—low (LMW), medium (MMW), high-molecular-weight (HMW)—with differing bioactivities. While is known influence adiponectin levels, evidence conflicting, few studies have explored isoform-specific changes. This study aimed evaluate...
Prevention of infectious diseases is based on host protection, especially using vaccines. Several factors have been linked to the acceptance vaccines in population. Chile achieved high COVID-19 vaccination coverage early pandemic. The study aimed determine prevalence antigens and antibodies, status, geographical distribution, related vaccine acceptability. In two Chilean cities, fourth round a population-based seroprevalence cross-sectional survey was conducted May 2024. 654 participants...
Chile is among the most successful nations worldwide in terms of its COVID-19 vaccine rollout. By 31 December 2021, 84.1% population was fully vaccinated, and 56.1% received booster doses using different vaccines. In this context, we aimed to estimate prevalence anti-SARS-CoV-2 antibodies following infection vaccination campaign. Using a three-stage stratified sampling, performed population-based cross-sectional serosurvey based on representative sample three Chilean cities. Selected...
The spatial-temporal dynamics of Bordetella pertussis remains as a highly interesting case in infectious disease epidemiology. Despite large-scale vaccination programs place for over 50 years around the world, frequent outbreaks are still reported many countries. Here, we use annual time series incidence from thirteen different regions Chile (1952–2010) to study Pertussis. period 1975–1995 was characterized by strong 4 year cycle, while last two decades (1990–2010) were resurgence without...
Using levels of neutralizing antibodies (nAbs), we evaluate the successful Chilean SARS-CoV-2 vaccine campaign, which combines different technologies and heterologous boosters. From a population-based study performed in November 2021, randomly selected 120 seropositive individuals, organized into six groups positive samples (20 subjects each) according to natural infection history five most frequent vaccination schemes. We conclude that booster dose, regardless technology or infection, mRNA...
In unequal economies, the spread of first waves COVID-19 was usually associated with low socioeconomic status individuals and their families. Chile exemplified this. By mid-2020, had one highest SARS-CoV-2 infection rates in world predominantly poorer areas. A year later, country launched a universal vaccination campaign based on national strategy immunization established 1975. 2022, presented coverages globally, reaching 94.3% population primary scheme by end 2022. This study analyzes...
The rapid emergence of COVID-19 necessitated policy responses worldwide, focusing on vaccination and mobility restrictions. However, studies individual non-pharmacological preventive measures are less common. In particular, Chile represents a unique scenario for analyzing the adoption changes amid aggressive communication campaigns. This study aims to provide insights into public adherence in face diseases, using cohort 386 participants from 2021 2022. was achieved by employing questionnaire...
The first wave of SARS-CoV-2 infection in Chile occurred during the cold season reaching a peak by end June 2020, with 80 % cases concentrated its capital, Santiago. main objective this study was to estimate attack rate large, densely populated city more than seven million inhabitants. Since number confirmed provides biased information due individuals' potential self-selection, mostly related asymptomatic patients and testing access, we measured antibodies against assess prevalence city, as...
The study compared immunity to the original SARS-CoV-2 virus (Wuhan) and Omicron variant using neutralizing antibodies (NAbs), that provide a good approximation of protective immunity. results might help determine immunization strategies.Unlike previous studies, we analyzed NAbs in random sample 110 IgG positive sera from individuals who participated population-based seroprevalence transversal study, carried out May 2022 two Chilean cities, country with high vaccination coverage.Our findings...
Abstract Objective: Chile is among the most successful nations worldwide in COVID-19 vaccine rollout. By December 31st, 2021, 84.1% of population was fully vaccinated, and 56.1% received booster doses using DIFFERENT TYPES OF VACCINES. In this context, we aimed to estimate anti-SARS-CoV-2 antibodies following infection vaccination campaign.Study design: Population-based cross-sectional serosurvey based on a representative sample cities Santiago, Coquimbo/La Serena, Talca used previous...
The rapid emergence of COVID-19 urged policy responses worldwide, focusing on vaccination and mobility restrictions. Chile represents a unique scenario for analyzing personal preventive measures amid intensive communication campaigns. This study aims to explore changes in population adherence non-pharmacological during the pandemic factors that explain this each year.
Older adults are at a higher risk of severe illness and death from COVID-19. This vulnerability increases in those who live long-term care facilities due to overcrowding, greater physical dependence, contact with health workers. Evidence on the impact pandemic these establishments lowand middle-income countries has been scant. study aims determine seroprevalence SARS-CoV-2 older people residing estimate infection after first wave pandemic.A cross-sectional design 2099 residents three regions...
Abstract Using levels of neutralizing antibodies (nAbs), we evaluate the successful Chilean SARS-CoV-2 vaccine campaign, which combines technologies and heterologous boosters. In 120 randomly selected seropositive individuals from a population-based study, conclude that booster dose, regardless technology or natural infection, mRNA vaccines significantly improve nAbs response.
Background: Seroprevalence studies provide an accurate measure of SARS-CoV-2 spread and the presence asymptomatic cases. They also information on uneven impact pandemic, pointing out vulnerable groups to prioritize who is particularly relevant in unequal societies. Here, we estimate prevalence antibodies three urban centers Chile model its spatial risk distribution. Methods :We conducted a population-based serosurvey Santiago, Talca, Coquimbo–La Serena (2,493 individuals) explored...
Introduction: Population in Arica's city has been exposed to arsenic of natural and anthropogenic origin. In 2009, an environmental health center was created order surveillance exposure polimetals, provide medical care population propose intervention measures. Objective: To assess factors that predict the urine concentration served at period 2009-2015. Method: The analyzed recruited Arica, Chile between 2009 2015. database provided included sociodemographic information, dwelling...
Abstract Objective: Chile is among the most successful nations worldwide in COVID-19 vaccine rollout. By December 31st, 2021, 84.1% of population was fully vaccinated, and 56.1% received booster doses using DIFFERENT TYPES OF VACCINES. In this context, we aimed to estimate anti-SARS-CoV-2 antibodies following infection vaccination campaign.Study design: Population-based cross-sectional serosurvey based on a representative sample cities Santiago, Coquimbo/La Serena, Talca used previous...