A5023561639- Synthesis and Biological Activity
- Research on scale insects
- Protein Tyrosine Phosphatases
- Agricultural Practices and Plant Genetics
- Insect-Plant Interactions and Control
- Drug-Induced Hepatotoxicity and Protection
- Insect Resistance and Genetics
- Galectins and Cancer Biology
- RNA modifications and cancer
- Aquaculture disease management and microbiota
- Insect Pest Control Strategies
- Traditional and Medicinal Uses of Annonaceae
- Nitrogen and Sulfur Effects on Brassica
- Venomous Animal Envenomation and Studies
- Phytochemicals and Medicinal Plants
- Chalcogenide Semiconductor Thin Films
- Lipid Membrane Structure and Behavior
- Diverse Scientific Research Studies
- Complementary and Alternative Medicine Studies
- Neurobiology and Insect Physiology Research
- Environmental Toxicology and Ecotoxicology
- Advances in Cucurbitaceae Research
- Hepatitis C virus research
- Redox biology and oxidative stress
- Animal Genetics and Reproduction
Manipal Academy of Higher Education
2024
National Institute of Solar Energy
2024
Institute of Biological Chemistry, Academia Sinica
2018-2023
Dr. Rajendra Prasad Government Medical College
2016-2023
Manipal University Jaipur
2023
Central Drug Research Institute
2022
Academia Sinica
2019-2021
National Tsing Hua University
2019-2021
Indian Institute of Natural Resins and Gums
2009-2020
Banaras Hindu University
1987-2020
Abstract T-Cell Protein Tyrosine Phosphatase (TCPTP, PTPN2) is a non-receptor type protein tyrosine phosphatase that ubiquitously expressed in human cells. TCPTP critical component of variety key signaling pathways are directly associated with the formation cancer and inflammation. Thus, understanding molecular mechanism activation regulation essential for development therapeutics. Under basal conditions, largely inactive, although how this achieved poorly understood. By combining...
When a mother's own milk is not available, WHO recommends pasteurised donor human as the first alternative.1WHODonor for low-birth-weight infants.https://www.who.int/elena/titles/donormilk_infants/en/Date: 2019Date accessed: April 30, 2020Google Scholar Human banks screen and recruit donors, have wide-ranging precautions to ensure safety of milk. Screened principally feeds babies very low birthweight, protecting them from range complications,2Quigley M Embleton ND McGuire W Formula versus...
The T-cell protein tyrosine phosphatase (TCPTP/PTPN2) targets a broad variety of substrates across different subcellular compartments. In spite that, the structural basis for regulation TCPTP's activity remains elusive. Here, we investigated whether TCPTP is regulated by potential allosteric site in comparable manner to its most similar PTP family member (PTP1B/PTPN1). We determined two crystal structures at 1.7 and 1.9 Å resolutions that include helix α7 C-terminus. Helix has been...
The myocardial ischaemia/reperfusion (I/R) injury is almost inevitable since reperfusion the only established treatment for acute infarction (AMI). To date there no effective strategy available reducing I/R injury. Our aim was to elucidate mechanisms underlying and develop a new attenuating damage it causes.Using mouse model by ligation of left anterior descending artery, we found an increase in activity protein tyrosine phosphatases (PTPs) myocardium during I/R. Treating I/R-mice with...
The structure and protein histochemistry of the hinge epidermis chequered water snake, Natrix piscator , throughout sloughing cycle has been described. Hinge epidermis, like scale undergoes cyclic changes in its organization six consecutive stages are itemized during one complete cycle. In contrast to beta layer, alpha presumptive layer could not be distinguished stratum germinativum, 1–2 layers undifferentiated epidermal cells, mesos Oberhautchen constitute stage 1. 2, cell increase number...
The structure and histochemistry of proteinaceous constituents in cellular components various layers the epidermis chequered water snake, Natrix piscator , throughout sloughing cycle have been described. Histologically, six consecutive stages are recognized during one complete cycle. In Stage I, immediately following sloughing, consists an inner stratum germinativum, or two undifferentiated epidermal cells new outer generation represented by Oberhautchen, β‐layer, mesos layer α‐layer which...
Polyphenol content and antioxidant activity in methanolic extracts of 10 fenugreek (Trigonella foenum graecum .L) genotypes from north India were evaluated, using different vitro assays, together with total carotenoid, α-tocopherol ascorbate content.The was evaluated (Phosphomolybdenum method), ferric reducing power (FRAP) assay, 1,1-diphenyl-2-picrylhydrazyl (DPPH) 2,2'-azinobis (3ethylbenzothiazoline)-6-sulphonate (ABTS) hydroxy radical scavenging superoxide nitric oxide...
Genetic elements are known to influence susceptibility tuberculosis (TB). P2X7R is a candidate gene with multiple single-nucleotide polymorphisms (SNPs) that has the potential an individual's ability kill intracellular pathogen Mycobacterium tuberculosis.To explore role of five functional in or resistance TB North Indian Punjabi population.A case-control study was conducted among 245 patients (145 pulmonary [PTB] and 100 extra-pulmonary [EPTB]) 247 healthy controls. DNA extracted from...
Two lepidopteran predators, Eublemma amabilis and Pseudohypatopa pulverea Aprostocetus purpureus an endoparasitoid have emerged as a major threat to lac cultivation. The objectives of the current study were identify some potential insecticides bio-pesticides against biotic stress crop. Field evaluation spinosad 2.5SC, indoxacarb 14.5SC, fipronil 5SC, ethofenprox 10EC three commercial formulations Bacillus thuringiensis var. kurstaki on rangeeni kusmi culture reveal significant reduction in...
BackgroundThe use of magnesium sulfate as an adjuvant in neuraxial block has gained popularity, with the aim improving and enhancing quality duration anesthesia, delaying onset postoperative pain, thus reducing demand for rescue analgesics. However, until today, there been no consensus regards ideal dose subarachnoid block. The present study was designed to examine whether addition intrathecal (50 100 mg) would enhance analgesic efficacy bupivacaine. We hypothesized that additive effect...
Crop protection plays a significant role in safeguarding productivity against insect pests. Likewise treatment of broodlac (seed material) is the starting point for achieving sustained lac production. Broodlac happen to be major source pest infestation on new crops. Laboratory and field experiments were conducted investigate biosafety chlorantraniliprole insect, Kerria lacca (Kerr) find out its efficacy key lepidopteran predators by dipping insecticide solutions 5, 10 15 min duration. Seven...
Treatment of broodlac (lac encrusted host sticks with fully mature living mother lac cells ready to produce young ones) is ecofriendly and cost effective tool for managing the biotic stress harbouring seed material. This study aims bring down pest population by treating Response insecticides on emergence predators parasitoids from treated was assessed under laboratory conditions dipping kusmi in insecticidal formulations subsequent inoculation host, Flemingia semialata field. Broodlac...