A5063880931- Autism Spectrum Disorder Research
- Child Nutrition and Feeding Issues
- Birth, Development, and Health
- Eating Disorders and Behaviors
- Reproductive System and Pregnancy
- Substance Abuse Treatment and Outcomes
- Respiratory viral infections research
- Microbial Metabolism and Applications
- Homelessness and Social Issues
- COVID-19 Impact on Reproduction
- Vibrio bacteria research studies
- Family Dynamics and Relationships
- Plant Pathogenic Bacteria Studies
- Virology and Viral Diseases
- Urban, Neighborhood, and Segregation Studies
- Vitamin D Research Studies
- Gestational Diabetes Research and Management
- Cannabis and Cannabinoid Research
- Essential Oils and Antimicrobial Activity
- Neurotransmitter Receptor Influence on Behavior
- Animal Virus Infections Studies
- Neuroendocrine regulation and behavior
- Child Development and Digital Technology
- Burkholderia infections and melioidosis
- Adolescent and Pediatric Healthcare
Government College University, Lahore
2025
University of the Punjab
2024
The University of Queensland
2016-2023
University of Veterinary and Animal Sciences
2015-2021
Queensland Centre for Mental Health Research
2019
Belmont Center for Comprehensive Treatment
1998-1999
University of Aberdeen
1972
North Eastern Space Applications Centre
1972
Leighton Hospital
1972
Migraine Trust
1972
Background. The contribution of human rhinovirus (HRV) to severe acute respiratory illness (ARI) is unclear. Objective. To assess the association between HRV species detection and ARI hospitalizations. Methods. Children <5 years old hospitalized for were prospectively enrolled December 2003 April 2005 in 3 US counties. Asymptomatic controls March 2004 October clinics. Nasal throat swab samples tested other viruses (ie, syncytial virus, metapneumovirus, parainfluenza influenza virus) by...
Newcastle disease (ND) is one of the most deadly diseases poultry around globe. The endemic in Pakistan and recurrent outbreaks are being reported regularly wild captive, rural commercial flocks. Though, efforts have been made to characterize causative agent some parts country, genetic nature strains circulating throughout currently lacking. To ascertain genetics NDV, 452 blood samples were collected from 113 flocks, originating all provinces Pakistan, showing high mortality (30–80%)....
Emerging evidence suggests that gestational or developmental vitamin D (DVD) deficiency is associated with an increased risk of autism spectrum disorder (ASD). ASD a neurodevelopmental characterized by impairments in social interaction, lack verbal and non-verbal communications, stereotyped repetitive behaviors hyper-activities. There are several other clinical features commonly comorbid ASD, including olfactory impairments, anxiety delays motor development. Here we investigate these animal...
Anthropogenic activities, such as industrial discharge, cargo handling, and untreated wastewater release, have led to significant heavy metal contamination along the Karachi coastline, posing risks marine life human health. Current study evaluated health associated with consuming five fish species (Trichiurus lepturus, Sillago sihama, Acanthopagrus arabicus, Otolithes cuvieri, Nemipterus japonicus) by analysing muscle tissues for arsenic, chromium, copper, nickel accumulation. japonicus...
Abstract Developmental vitamin D (DVD)-deficiency is an epidemiologically established risk factor for autism. Emerging studies also highlight the involvement of gut microbiome/gut physiology in The current study aims to examine effect DVD-deficiency on a broad range autism-relevant behavioural phenotypes and health. Vitamin deficient rat dams exhibited altered maternal care, DVD-deficient pups showed increased ultrasonic vocalizations as adolescents, social behaviour impairments repetitive...
A multidisciplinary, collaborative project was conducted to determine the prevalence and distribution of soil-borne zoonotic pathogens in Lahore district Pakistan ascertain its Public Health Significance. Using a grid-based sampling strategy, soil samples (n = 145) were collected from villages 29, 5 samples/village) examined for Bacillus anthracis, Burkholderia mallei/pseudomallei, Coxiella burnetii, Francisella tularensis, Yersinia pestis using real time PCR assays. Chemical analysis also...
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders which are more common in males. The 'prenatal sex steroid' hypothesis links excessive sex-steroid exposure during foetal life with the behavioural differences observed ASD. However, reason why steroid may be remains unclear. Epidemiological studies have identified several environmental risk factors associated ASD, including developmental vitamin D (DVD) deficiency. We demonstrated an animal model that DVD-deficiency...
Abstract Dopaminergic (DA) dysfunction is a significant feature in the pathophysiology of schizophrenia. Established developmental risk factors for schizophrenia such as maternal immune activation (MIA) or vitamin D (DVD) deficiency, when modelled animals, reveal differentiation early DA neurons foetal brains delayed suggesting this may be convergent aetiological pathway. Here we have assessed effects prenatal hypoxia, another well-known factor schizophrenia, on developing systems. Pregnant...
Aim of the present study was to determine In-vitro antibacterial activity ethanolic extract E. globulus leaves against common multidrug resistant poultry pathogens. Phytochemical analysis through HPLC revealed that kaempeferol (7.315min) followed by querecetin (6.655min) and myrecetin (3.655min). Percent area (6826.88%) highest, (5516.22%) (163.748%). investigation GCMS showed highest retention time (min) α-pinene (20.43) α-terpineol (20.15) accompanied spathulenol (11.97), piperitone...
ABSTRACT The characteristics that predicted to treatment outcome were determined separately for 157 adolescent drag abusers who received inpatient and 296 outpatient treatment. criterion used was the degree of reduction in substance use/abuse. Of 33 predictor variables analyzed, twelve found predict outcome, fifteen outcome. Only two variables, school, not considering use be harmful one's health worse both settings. A number prognostic adolescents are different from those reported earlier...
ABSTRACT It is a common belief that growing up without father, and in the poverty related to fatherlessness, are "root causes" of crime drug trafficking, possibly also substance use for adolescent males. This popular or assumption most often applied sons families this inner city African-American community. To test hypothesis, following two groups subjects were compared on their illegal behavior, alcohol use/abuse: (1) who grew with both biological parents, (2) living only mother siblings,...
Abstract An increase in dopamine (DA) synthesis capacity the dorsal striatum (DS) during prodromal stage of schizophrenia becomes more pronounced as patients progress to full disorder. Understanding this progression is critical intervening disease course. We developed an animal model—Enhanced Dopamine Prodromal Schizophrenia (EDiPS)—which uses a genetic construct DA DS male rats. assessed pre-pulse inhibition (PPI) and amphetamine (AMPH)-induced locomotion (0.6 mg/kg) EDiPS animals...
ABSTRACT In a study of multi-city sample adolescent substance abusers (N = 487), it was found that the degree or severity use and related problems less for African-American than White subjects, except crack heroin. This confirmation findings earlier research occurred after controlling differences between Black subsamples on types family organization, living arrangements, SES, whether welfare. SES not to be significantly use/abuse; but there use/abuse if An unexpected finding no significant...
The drug-resistance behavior of Methicillin-resistant Staphylococcus aureus (MRSA) has made it difficult to treat. This study aimed discover some fruit juice's anti-MRSA potential and the presence enterotoxin genesin MRSA.MRSA strains were confirmed phenotypically by disc diffusion method. well-diffusion method Minimum inhibitory concentration (MIC)were used determine antibacterial effects juices. Congo red test ring tests performed analyze biofilm-forming ability. PCR detected...
Background: Staphylococcus aureus (S. aureus) is one of the leading causes skin infections and food poisoning worldwide. Citrus fruits enriched with phytochemicals can exhibit anti-staphylococcal activity. Objective: The study aims to investigate in vitro susceptibility citrus against S. harboured enterotoxin genes among handlers, personnel, environment. Methods: was isolated from Methicillin-Resistant (MRSA) screening performed using cefoxitin antibiotic discs. antimicrobial activity...
Abstract Developmental vitamin D (DVD)-deficiency is an epidemiologically established risk factor for autism. Emerging studies also highlight the involvement of gut microbiome/gut physiology in The current study aims to examine effect DVD-deficiency on a broad range autism-relevant behavioural phenotypes and health. Vitamin deficient rat dams exhibited altered maternal care, DVD-deficient pups showed increased ultrasonic vocalizations as adolescents, social behaviour impairments repetitive...
The present study was designed to evaluate the antimicrobial activity of E. globulus leaves in broiler chicks. Total (n=255) day-old chicks were segregated into five groups i.e. Pathogenic coli, S. pullorum, gallinarum and C. perfringens type A control negative group. Each bacterial challenged (1x 107 CFU) group divided positive, antibiotic, probiotic Experimental birds exposed at different ages. At 35th day experiment log reduction for each determined. highest coli Type colonies count found...
Preeclampsia is a pregnancy disorder characterized by hypertension. Epidemiological studies have associated preeclampsia with an increased risk of neurodevelopmental disorders in offspring, such as autism and schizophrenia. has also been linked maternal vitamin D deficiency, another candidate factor autism. Our laboratory established gestational vitamin-D-deficient rat model that shows consistent robust behavioural phenotypes autism- schizophrenia-related animal models. Therefore, we...