A5023691157- Gastric Cancer Management and Outcomes
- Food Security and Health in Diverse Populations
- Esophageal Cancer Research and Treatment
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Obesity, Physical Activity, Diet
- COVID-19 Pandemic Impacts
- Urban Agriculture and Sustainability
- Health Systems, Economic Evaluations, Quality of Life
- Colorectal Cancer Treatments and Studies
- Economic and Financial Impacts of Cancer
- Eosinophilic Esophagitis
- Cardiovascular Health and Risk Factors
- Radioactive Decay and Measurement Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- COVID-19 and Mental Health
- Diabetes Management and Education
- Diet and metabolism studies
- Chronic Disease Management Strategies
- Child Nutrition and Water Access
- Pharmacology and Obesity Treatment
- Bariatric Surgery and Outcomes
- Medical Imaging Techniques and Applications
- Obesity and Health Practices
- Child Nutrition and Feeding Issues
Columbia University
2019-2023
Tufts University
2022-2023
Columbia University Irving Medical Center
2019-2022
Health Innovations (United States)
2021
University of Missouri
2011
Breast Cancer Care
2011
Abstract Objective: To examine associations between sociodemographic and mental health characteristics with household risk for food insecurity during the COVID-19 outbreak. Design: Cross-sectional online survey analysed using univariable tests a multivariable logistic regression model. Setting: The United States week of 30 March 2020. Participants: A convenience sample 1965 American adults Amazon’s Mechanical Turk platform. Participants reporting prior to pandemic were excluded from...
Background Produce prescription programs, providing free or discounted produce and nutrition education to patients with diet-related conditions within health care systems, have been shown improve dietary quality cardiometabolic risk factors. The potential impact of implementing programs for diabetes on long-term gains, costs, cost-effectiveness in the United States has not established. Methods Results We used a validated state-transition microsimulation model (Diabetes, Obesity,...
Importance Medically tailored meals (MTMs) are associated with lower health care utilization among patients complex diet-related diseases but not a covered benefit in Medicare or Medicaid. The potential impact of extending insurance coverage for MTMs nationally remains unknown. Objective To estimate 1- and 10-year changes annual hospitalizations, expenditures, overall policy cost-effectiveness national MTM US disease limited instrumental activities daily living who have Medicaid, Medicare,...
Bariatric surgery is recommended for patients with severe obesity (body mass index ≥40) and type 2 diabetes (T2D). However, the most cost-effective treatment remains unclear may depend on patient's T2D severity.
The Food and Drug Administration has approved several pharmacotherapies for the treatment of obesity. This study assesses cost-effectiveness six lifestyle intervention people with mild obesity (body mass indices [BMIs] 30 to 35).
COVID-19 has affected the health and well-being of almost every American. The aim this study was to examine sustained impacts prevention measures on diet exercise habits, risk for food insecurity, quality life among adults in U.S. We conducted a longitudinal using convenience sample participants recruited via Amazon's Mechanical Turk (MTurk) platform between March 30 April 7, 2020, 8 months into outbreak, from November 2 21, 2020. compared self-reported habits insecurity shortly after...
Abstract The Food Compass is a nutrient profiling system (NPS) to characterize the healthfulness of diverse foods, beverages and meals. In nationally representative cohort 47,999 U.S. adults, we validated person’s individual Score (i.FCS), ranging from 1 (least healthful) 100 (most based on cumulative scores items consumed, against: (a) Healthy Eating Index (HEI) 2015; (b) clinical risk factors health conditions; (c) all-cause mortality. Nationally, mean (SD) i.FCS was 35.5 (10.9)....
Current guidelines recommend surveillance for patients with nondysplastic Barrett's esophagus (NDBE) but do not include a recommended age discontinuing surveillance. This study aimed to determine the optimal last of NDBE stratified by sex and level comorbidity.We used 3 independently developed models simulate diagnosed NDBE, varying in age, sex, comorbidity (no, mild, moderate, severe). All had received regular until their current age. We calculated incremental costs quality-adjusted...
Critical temporal changes such as weekly fluctuations in surveillance systems often reflect laboratory testing capacity, access to or healthcare facilities, preferences. Many studies have noted but few described day-of-the-week (DoW) effects SARS-CoV-2 over the major waves of novel coronavirus 2019 pandemic (COVID-19). We examined DoW by non-pharmaceutical intervention phases adjusting for wave-specific signatures using John Hopkins University’s (JHU’s) Center Systems Science and Engineering...
Summary Objective To test the hypothesis that children in Food FARMacia—a six‐month food insecurity intervention from May 2019 to January 2020—would have smaller age‐adjusted, sex‐specific body mass index (BMI z ) gains than matched counterparts. Methods In this proof‐of‐concept study, we performed a difference‐in‐differences (DiD) analysis of propensity‐score cohort among paediatric primary care patients aged <6 years with household insecurity. Children anthropometric measures prior and...
Abstract Objective To examine associations between sociodemographic and mental health characteristics with household food insecurity as a result of the COVID-19 outbreak. Design Cross-sectional online survey analyzed using univariable tests multivariable logistic regression model. Setting The United States during week March 30, 2020. Participants Convenience sample 1,965 American adults Amazon’s Mechanical Turk (MTurk) platform. reporting prior to pandemic were excluded from analyses....
The 5-year survival rate of patients with metastatic gastric cancer (GC) is only 5%. However, trials have demonstrated promising antitumor activity for targeted therapies/immunotherapies among chemorefractory GC patients. Pembrolizumab has shown particular efficacy programmed death ligand-1 (PD-L1) expression and high microsatellite instability (MSI-H). aim this study was to assess the effectiveness cost-effectiveness biomarker-guided second-line treatment.We constructed a Markov...
Background Few simulation models have incorporated the interplay of diabetes, obesity, and cardiovascular disease (CVD); their upstream lifestyle biological risk factors; downstream effects on health disparities economic consequences. Methods We developed validated a US Diabetes, Obesity, Cardiovascular Disease Microsimulation (DOC-M) model that incorporates demographic, clinical, factors to jointly predict overall racial-ethnic groups-specific CVD, cause-specific mortality for adult...
Abstract Background The 2020 National Comprehensive Cancer Network guidelines recommend neoadjuvant FOLFIRINOX or gemcitabine plus nab‐paclitaxel (G‐nP) for borderline resectable/locally advanced pancreatic ductal adenocarcinoma (BR/LA PDAC). Aim purpose of our study was to compare treatment outcomes, toxicity profiles, costs, and quality‐of‐life measures between these two treatments further inform clinical decision‐making. Methods Results We developed a decision‐analytic mathematical model...
e15517 Background: Gastric cancer is the third leading cause of cancer-related mortality, with only a 30% five-year survival rate. Patients who progress after one round systemic therapy face an especially poor prognosis. The National Comprehensive Cancer Network guidelines include both pembrolizumab (PEM) and ramucirumab plus paclitaxel (RAM/PAC) as second-line (2L) for gastric based on data from Phase II KEYNOTE-059 III RAINBOW trials, respectively. Recently, KEYNOTE-061 trial reported...
e16793 Background: The 2019 NCCN guidelines recommend neoadjuvant FOLFIRINOX or gemcitabine plus nab-paclitaxel (G-nP) for locally advanced and borderline resectable pancreatic ductal adenocarcinoma (BR/LA PDAC). Neoadjuvant G-nP have yet to be directly compared in a prospective, randomized trial with BR/LA PDAC patients. purpose of our study was incorporate treatment outcomes, toxicity profiles, costs, quality-of-life measures further inform clinical decision-making. Methods: We developed...