- Oral health in cancer treatment
- Head and Neck Cancer Studies
- Dental Implant Techniques and Outcomes
- Sports Performance and Training
- Sports injuries and prevention
- Epilepsy research and treatment
- Dental materials and restorations
- Pharmacological Effects and Toxicity Studies
- Cancer Diagnosis and Treatment
- Neonatal and fetal brain pathology
- Bone Tissue Engineering Materials
- Muscle activation and electromyography studies
- Traumatic Brain Injury Research
- Cardiovascular and exercise physiology
- Titanium Alloys Microstructure and Properties
- Neurological and metabolic disorders
- Musculoskeletal Disorders and Rehabilitation
- Dental Erosion and Treatment
- Advanced Sensor and Energy Harvesting Materials
- Shoulder Injury and Treatment
- Laser Applications in Dentistry and Medicine
- Archaeology and Natural History
- Surgical site infection prevention
- Antibiotic Use and Resistance
- Pharmaceutical Practices and Patient Outcomes
University of Bristol
2014-2023
Musgrove Park Hospital
2020-2023
University Of Bristol Dental Hospital
2014-2023
University Hospitals Bristol and Weston NHS Foundation Trust
2022
University Hospitals Bristol NHS Foundation Trust
2022
Somerset NHS Foundation Trust
2021
Kent and Canterbury Hospital
1998
King's College Hospital
1998
Epilepsy Society
1998
National Hospital for Neurology and Neurosurgery
1995-1998
Sudden death, often seizure related, may occur in patients with epilepsy. Population-based incidence is probably on the order of 1:1,000/year. The much higher selected groups, however. We wished to establish sudden unexpected death (SUD) a young cohort severe epilepsy and learning difficulties. study included 310 pupils enrolled at special residential school between April 1970 1993. follow-up period totaling 4,135 person-years residence as well time after leaving. Age sex standardized...
To assess the effects of concurrent strength (S) and endurance (E) training on S E development, one group (4 young men 4 women) trained leg for other (S+E). A second men, (E+S). consisted five 3-min bouts a cycle ergometer at power output corresponding to that requiring 90-100% oxygen uptake during maximal exercise (VO2 max). six sets 15-20 repetitions with heaviest possible weight press (combined hip knee extension) machine. Training was done 3 days/wk 22 wk. Needle biopsy samples from...
Substantial psychological and neurobehavioural evidence is available to support the hypothesis that traumatic brain injury (TBI) a risk factor for subsequent psychiatric disorders. However, studies utilizing established diagnostic schemes study these outcomes after TBI are scarce, no have included an assessment of personality disorders in addition major This utilizes structured interviews measure prevalence DSM-III(R) sample 18 subjects derived from rehabilitation programme. Results revealed...
To compare the responses to doing strength (S) training on alternate days with endurance (E) vs both types of same per week, seven young men (group A-2 d) did S and E together in single sessions 2 d·wk−1 for 20 wk. A second group (B-4 d, N = 8) other d·wk−1. was six eight sets 15–20 RM a leg press weight machine. 3-min bouts cycle ergometer exercise at 90–100% V̇O2max B-4 d (25%) increased 1 more (P < 0.05) than (13%), but groups similarly (A-2 knee extensor (31%, 34%) flexor (12%, 14%)...
<h3>OBJECTIVES</h3> To study the circumstances of death in sudden epilepsy. <h3>METHODS</h3> Self referred bereaved relatives patients with epilepsy who had died suddenly were interviewed information obtained substantiated through other sources—namely, coroners’ officers’ reports, postmortem previous medical records, and EEG reports. <h3>RESULTS</h3> Of 34 cases, 26 classified as unexpected deaths (SUDEP). Twenty four cases SUDEP unwitnessed. Evidence indicative or suggestive a seizure was...
The M wave (muscle compound action potential) has been shown to enlarge between successive 3-s voluntary contractions of the human thenar and extensor digitorum brevis (EDB) muscles. changes, which affected both amplitude area wave, were more obvious in than EDB In muscles mean was already significantly enlarged after first contraction close maximal value by third (mean increase 23.6 +/- 12.6% control). gradual, reaching a maximum 29.3 14.1% at 100 s. After ceased, subsided rapidly had...
Severe amotivation, apathy, and abulia, significantly retard rehabilitation following traumatic brain injury. Preliminary, uncontrolled research has suggested possible benefit with amantadine for this behavioural syndrome. This N of 1, double-blind, placebo-controlled study employed 100 mg three times daily in one such patient. Therapists nurses completed inventories scoring efforts towards initiation therapeutic activities during each session, progress therapy, participation therapy. Four...
Six women and 6 men trained the elbow flexors 3 days per week for 20 wks, one arm performing in each session 3-5 sets of 10 maximal concentric actions on an accommodating resistance device, other 8-12 coupled eccentric/concentric a weight training device. With results collapsed across two modes, made significantly (p < 0.05) greater relative increases than strength measured (116 vs. 46%) (99 devices, absolute (3.5 -1.3 N.m) (13.7 -3.2%) isokinetic dynamometer. Absolute (cm2) (%) biceps,...
There is growing concern about the quality and safety of prescribing in UK. Added to increasing prevalence antimicrobial resistance, this makes a persuasive case for improving education antimicrobials within broader programme prescribing. Moreover, need not confined professionals who prescribe antimicrobials, it extends all are involved patient's journey from presentation outcome. The work Specialist Advisory Committee on Antimicrobial Resistance Professional Education has focused two areas....
Objectives Chlorhexidine ( CHX ) is in widespread use as a topical antimicrobial agent. Within the field of oral medicine, it used prevention ventilator‐associated pneumonia well treatment candidosis and microbial‐associated lichenoid reactions. The objective this study was to develop strategy for controlled, sustained delivery using nanoparticle technology. Methods applied hydroxyapatite, selected tooth analogue, conventional digluconate solutions aqueous suspensions hexametaphosphate...
Dental implants are an increasingly popular way to replace missing teeth. Whilst implant survival rates high, a small number fail soon after placement, with various factors, including bacterial contamination, capable of disrupting osseointegration. This work describes the development chlorhexidine-hexametaphosphate coatings for titanium that hydrolyse release antiseptic agent chlorhexidine. The aim was develop coating released sufficient chlorhexidine prevent biofilm formation, whilst...
Blimkie, C. J.R.; MacDougall, D.; Sale, Thonar, E.; Smith, K.; Garner, S. Author Information
Background: Oral cancer has the highest incidence of head and neck it is reported that number cases are rising every year. Many patients face struggle with speech, chewing, swallowing which can largely affect their nutrition as well psychosocial health, possibly due to altered anatomy oral cavity facial disfigurement. Patient expectations outcomes following treatment dental rehabilitation under in UK. Aim/Hypothesis: The aim this study was report on patient measures (PROMS) implants...
MacDougall, D.; Sale, Jacobs, I.; Garner, S.; Moroz, Dittmer, D. Author Information
To determine the success, survival, peri-implant health and prosthetic complications in head neck cancer patients receiving oral rehabilitation utilising dental implants between 2008 present day.Service evaluation. Survival Group: Retrospective review of records to implant survival complications. Success Examination success health.Survival 260 81 individuals, median follow up 49.2 months. 89.3% at 96 months, no further failures 133 40.9% individuals required repair or remake prosthesis by 72...
Blimkie, C. J.R.; MacDougall, D.; Sale, Thonar, E.; Smith, K.; Garner, S. Author Information
Radiotherapy to the head and neck region has oral side effects can lead catastrophic dental deterioration, but this is largely preventable. This article describes case of a patient whose dentition was irreparably compromised after radical radiotherapy for soft palate cancer. The had fairly well maintained at pre-radiotherapy screen, – notably dry mouth reduced access cleaning coupled with high-sugar diet intended aid recovery, led rapid progression caries tooth wear. Additionally, service...