Frances E. Broyles

ORCID: 0000-0003-3680-197X
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About
Contact & Profiles
Research Areas
  • Diabetes Management and Research
  • Pituitary Gland Disorders and Treatments
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipoproteins and Cardiovascular Health
  • Diabetes and associated disorders
  • Growth Hormone and Insulin-like Growth Factors
  • Diabetes Treatment and Management
  • Diet and metabolism studies
  • Pancreatic function and diabetes
  • Metabolism, Diabetes, and Cancer
  • Adrenal Hormones and Disorders
  • Adrenal and Paraganglionic Tumors
  • Blood Pressure and Hypertension Studies
  • Adipose Tissue and Metabolism
  • Cancer, Lipids, and Metabolism
  • Cardiovascular Health and Disease Prevention
  • Vitamin K Research Studies
  • Hormonal Regulation and Hypertension
  • Stress Responses and Cortisol
  • Estrogen and related hormone effects
  • Pharmaceutical Economics and Policy
  • Pharmaceutical Practices and Patient Outcomes
  • Glioma Diagnosis and Treatment
  • Hormonal and reproductive studies
  • Reproductive Health and Contraception

Group for the Analysis of Development
2023-2025

Rainier Clinical Research Center
2025

Neuroscience Institute
2016-2017

Swedish Medical Center
2016-2017

University of Louisville
2016

Neurological Surgery
2016

University of Washington
1994-2001

University of Iowa
1996

Northwest University
1996

Pacific Biomarkers (United States)
1996

Automated insulin delivery (AID) systems have been shown to be beneficial for patients with type 1 diabetes, but data are needed from randomized, controlled trials regarding their role in the management of insulin-treated 2 diabetes. In this 13-week, multicenter trial, adults diabetes were randomly assigned a 2:1 ratio receive AID or continue pretrial insulin-delivery method (control group); both groups received continuous glucose monitoring (CGM). The primary outcome was glycated hemoglobin...

10.1056/nejmoa2415948 article EN New England Journal of Medicine 2025-03-19

OBJECTIVE Successful transsphenoidal surgery for adrenocorticotropin hormone (ACTH)–producing pituitary tumors is associated with subnormal postoperative serum cortisol levels, which may guide decisions regarding immediate reoperation. However, little known about the detailed temporal course of changes in period, and relationship dynamics to remission late recurrence. METHODS A single-center retrospective cohort analysis was performed all patients undergoing from 2007 through 2015....

10.3171/2017.6.jns17635 article EN Journal of neurosurgery 2017-12-22

This study examined whether psychological stress and the infusion of epinephrine increase plasma lipid apoprotein concentrations in normolipidemic hyperlipidemic men. Subjects were studied during three separate 6-hour laboratory sessions: a control session, which subjects rested quietly while blood samples hemodynamic measurements obtained; presented with two challenging mental tasks, followed by quiet rest; an received low-dose rest. The manipulations produced expected changes...

10.1097/00006842-199503000-00009 article EN Psychosomatic Medicine 1995-01-01

BACKGROUND: Atorvastatin, a new HMG-CoA reductase inhibitor in clinical development has demonstrated an acceptable safety profile and marked cholesterol triglyceride reduction at doses ranging from 10-80 mg/day. Since bile acid sequestering resins are often used combination with HMGRIs to enhance reduction, this trial was conducted explore the use of atorvastatin alone combined colestipol patients primary hyperlipidemia. METHODS AND RESULTS: One hundred six low-density lipoprotein (LDL) >4.1...

10.1177/107424849600100205 article EN Journal of Cardiovascular Pharmacology and Therapeutics 1996-04-01

OBJECTIVE: To determine the efficacy and safety of pravastatin in treatment subjects with Type III hyperlipoproteinemia. DESIGN: Randomized, double-blind, placebo-controlled, crossover study. SETTING: Four lipid research clinics United States. PATIENTS: Twenty between 18 70 years old three diagnostic features hyperlipoproteinemia: very-low-density lipoprotein cholesterol (VLDL-C)/total plasma triglyceride ratio excess 0.30; beta-migrating VLDL pattern on agarose-gel electrophoresis;...

10.1097/00045391-199611000-00004 article EN American Journal of Therapeutics 1996-11-01

The urinary free cortisol (UFC) test is widely used for the screening of Cushing's syndrome. This case study illustrates potential failure UFC to correctly diagnose disease (CD), indicating that use other complementary tests may be necessary this in some cases. (CD) a condition characterized by elevation levels caused an ACTH-secreting pituitary adenoma. Failure accurately identify and treat patients with could lead increased risk mortality worsened morbidity compared control population....

10.1002/ccr3.647 article EN cc-by-nc-nd Clinical Case Reports 2016-11-09

Objective: Pasireotide is approved for treatment of adults with Cushing disease (CD) persistent hypercortisolism whom surgery has failed or not an option. Effective medical therapy CD may increase the susceptibility relative hypocortisolism during acute stress because a patient's inability to compensate by increasing endogenous adrenocorticotropic hormone (ACTH) and cortisol secretion. We describe patient on pasireotide 7 years in biochemical eucortisolemia was achieved but subsequently...

10.4158/ep171745.cr article EN cc-by-nc-nd AACE Clinical Case Reports 2017-05-24

Heinonen, Therese M; Schrott, Helmut; Broyles, Frances; Shurzinske, Linda; Black, Donald M Author Information

10.1097/00042192-199603040-00093 article EN Menopause The Journal of The North American Menopause Society 1996-01-01
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