- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Hepatitis C virus research
- Pediatric Hepatobiliary Diseases and Treatments
- Diversity and Career in Medicine
- Gastrointestinal Bleeding Diagnosis and Treatment
- Nutrition and Health in Aging
- Pancreatic and Hepatic Oncology Research
- Hepatitis B Virus Studies
- Pancreatitis Pathology and Treatment
- Colorectal Cancer Screening and Detection
- Antiplatelet Therapy and Cardiovascular Diseases
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- SARS-CoV-2 and COVID-19 Research
- Lung Cancer Treatments and Mutations
- Viral Infections and Outbreaks Research
- Atrial Fibrillation Management and Outcomes
- Multiple and Secondary Primary Cancers
- Healthcare cost, quality, practices
- Inflammatory Biomarkers in Disease Prognosis
- Neuroendocrine Tumor Research Advances
- Head and Neck Cancer Studies
Montefiore Medical Center
2023-2025
Aga Khan University
2012-2025
Aga Khan University Hospital
2012-2024
Albert Einstein College of Medicine
2023
Rosalind Franklin University of Medicine and Science
2021
Northwestern Medicine
2021
Karachi School for Business and Leadership
2020
Grammar School
2020
Sindh Agriculture University
2018
Aga Khan University
2013-2017
Liver injury due to dengue viral infection is not uncommon. Acute liver a severe complicating factor in dengue, predisposing life-threatening hemorrhage, Disseminated Intravascular Coagulation (DIC) and encephalopathy. Therefore we sought determine the frequency of hepatitis compare outcome (length stay, hospital mortality, complications) between patients Dengue who have mild/moderate (ALT 23-300 IU/L) v/s acute > 300 IU/L). A Cohort study inpatients with done at Aga Khan University Hospital...
HDV infection leads to the most aggressive form of human viral hepatitis for which there is no FDA-approved therapy. PEG IFN-lambda-1a (Lambda) has previously demonstrated a good tolerability profile in HBV and HCV patients compared IFN-alfa. The goal Phase 2 LIMT-1 trial was evaluate safety efficacy Lambda monotherapy with HDV.
Abstract Background The global use of kidney replacement therapy (KRT) has increased, mirroring the incidence acute injury and chronic disease. Despite its growing clinical usage, patient outcomes with KRT modalities remain controversial. In this meta-analysis, we sought to compare mortality patients any disease requiring peritoneal dialysis (PD), hemodialysis (HD), or continuous renal (CRRT). Methods investigation was conducted according Preferred Reporting Items for Systematic Reviews...
Females and ethnic minorities are underrepresented in the first senior authorships positions of academic publications. This stems from various structural systemic inequalities discrimination journal peer-review process, as well educational, institutional, organizational cultures.A retrospective bibliometric study design was used to investigate representation gender racial/ethnic groups authorship critical care randomized controlled trials 12 high-impact journals 2000 2022.In 1398 included...
Summary Goat farming in Pakistan depends on indigenous breeds that have adapted to specific agro‐ecological conditions. has a rich resource of goat breeds, and the genetic diversity these is largely unknown. In this study, population structure were characterized from seven using 50K SNP chip. The analysis showed Bugi toori goats highest inbreeding level, consistent with linkage disequilibrium, lowest long run heterozygosity segments. This indicates breed should be prioritized future...
Cirrhosis produces variety of symptoms which eventually lead to a negative impact on Health Related Quality Life (HRQOL). The general aim this study was evaluate the magnitude poor HRQOL and assess factors related with in patients CLD Pakistan.This cross sectional conducted gastroenterology outpatient clinics Aga Khan University Hospital, Karachi adult cirrhosis. In chronic liver disease questionnaire (CLDQ) used these CLDQ score as an outcome measure determine HRQOL.273 participants were...
With 4.9 to 35 instances per 100000 cases, hyperparathyroidism is one of the rarest causes acute pancreatitis. The major cause primary a parathyroid adenoma, which can manifest clinically in various ways.
The analysis of autopsy data from 1928 to 1972 shows that the relative frequency lung cancer has undergone a fourfold increase till about 1962, and since then remained practically constant. right is more often seat carcinoma than left upper lobes lower lobes. For females upper-lower lobe asymmetry not significant. nonuniform distribution tumor sites explained on basis 'contact hypothesis'. Some age sex factors have been studied.
Acute pancreatitis (AP) is a multi-causal disease with high rate of hospitalisation. Only few clinical studies have investigated the aetiological background, severity, and outcome AP in Pakistan. Hence, this study was carried out to determine aforementioned factors correlate them outcomes tertiary care setting. This cross-sectional, retrospective conducted at Department Gastroenterology, Aga Khan University Hospital, Karachi, from January 1, 2022, December 31, 2022. Data analysed using...
Malnutrition is a common problem in patients with liver cirrhosis and tools for nutritional assessment are under debate. We conducted this study to assess prevalence of malnutrition cirrhotic using PCM score BIA. Additionally we compared BIA detecting patient population. This was cross sectional two tertiary care hospitals Karachi Pakistan on adults cirrhosis. assessed by anthropometric measurements biological specimens (ii) Body cell mass as estimated the present 122 (73%) which most had...
Gastro-pleural and gastro-cutaneous fistulae formation are rare yet life-threatening complications post-bariatric surgery. To our knowledge so far only limited cases of gastro-pleural post gastric sleeve surgery have been reported in the literature with their corresponding management. Therefore, we reporting a case placement an endoscopic stent management fistula laparoscopic gastrectomy.A 42 years old Pakistani, female morbidly obese patient, underwent gastrectomy. Within week after...
The autopsy data from 1928 to 1972 the Pathology Department of Wilhelminen Hospital have been evaluated. During this period 1,296 cases carcinoma large intestine were observed. incidence rate colorectal has steadily increasing, and during past 30 years doubled. relative proportion colon rectum (2:1) remained remarkably constant all period. It is shown that different sections significantly rates occurrence carcinoma. character frequency-site distribution identical for two sexes unchanged over...