- SARS-CoV-2 detection and testing
- Cell Image Analysis Techniques
- SARS-CoV-2 and COVID-19 Research
- Biosensors and Analytical Detection
- Respiratory viral infections research
- Urological Disorders and Treatments
- Computational Drug Discovery Methods
- Cholinesterase and Neurodegenerative Diseases
- Water Quality and Pollution Assessment
- Growth Hormone and Insulin-like Growth Factors
- Sexual Differentiation and Disorders
- Pharmacogenetics and Drug Metabolism
- Water Quality Monitoring and Analysis
- PI3K/AKT/mTOR signaling in cancer
- Metabolism, Diabetes, and Cancer
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Water Quality Monitoring Technologies
Centro de Excelencia en Procesos y Productos de Córdoba
2009-2023
Ministerio de Ciencia y Tecnología
2009
Georg Speyer Haus
2003
Human carboxylesterases 1 and 2 (CES1 CES2) catalyze the hydrolysis of many exogenous compounds. Alterations in CES sequences could lead to variability both inactivation drugs activation prodrugs. The human CES1 gene encodes for enzyme carboxylesterase 1, a serine esterase governing metabolic deactivation numerous therapeutic agents. Some theses are antiviral oseltamivir used treat some types influenza infections methylphenidate employed treatment patients with attention deficit. Gly143Glu...
Background The current COVID-19 pandemic has overloaded the diagnostic capacity of laboratories by gold standard method rRT-PCR. This disease a high spread rate and almost quarter infected individuals never develop symptoms. In this scenario, active surveillance is crucial to stop virus propagation. Methods Between July 2020 April 2021, 11,580 oropharyngeal swab samples collected in closed semi-closed institutions were processed for SARS-CoV-2 detection pools, implementing strategy first...
The emergence of more virulent and transmissible variants the type 2 coronavirus causing severe acute respiratory syndrome (SARS-CoV-2) has triggered expensive genomic surveillance that proves difficult to sustain over time.Development a simple low-cost one-step RT-qPCR assay with High Resolution Melting (HRM-RTqPCR) analysis for detection mutations associated SARS-CoV-2 Gamma (P.1) Lambda (C.37) variants. In silico melting simulation was performed select amplicons in spike-gene identify...
The emergence of more virulent and transmissible variants the type 2 coronavirus causing severe acute respiratory syndrome (SARS-CoV-2) has triggered expensive genomic surveillance that proves difficult to sustain over time. Development a simple low-cost one-step RT-qPCR assay with High Resolution Melting (HRM-RTqPCR) analysis for detection mutations associated SARS-CoV-2 Gamma (P.1) Lambda (C.37) variants. In silico melting simulation was performed select amplicons in spike-gene identify...
The study of inland water properties and dynamics is crucial for understanding processes like eutrophication algal blooms. This integrates field, lab, satellite data analysis to investigate the interplay between chemical, biological, optical their relationship with quality in a highly eutrophic reservoir. Environmental analysis, including rainfall, surface temperature, levels, reveals significant influence on dominance different algae species. Higher precipitation leads cooler temperatures...
Abstract Background The current COVID-19 pandemic has overloaded the diagnostic capacity of laboratories by gold standard method rRT-PCR. This disease a high spread rate and almost quarter infected individuals never develop symptoms. In this scenario, active surveillance is crucial to stop virus propagation. Methods Between July 2020 April 2021, 11580 oropharyngeal swab samples collected in closed semi-closed institutions were processed for SARS-CoV-2 detection pools, implementing strategy...