A5084112377- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Biosensors and Analytical Detection
- Respiratory viral infections research
- COVID-19 epidemiological studies
- Long-Term Effects of COVID-19
- Tuberculosis Research and Epidemiology
- Immunotherapy and Immune Responses
- Sports Performance and Training
- vaccines and immunoinformatics approaches
- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Sports and Physical Education Research
- Animal Virus Infections Studies
- Sepsis Diagnosis and Treatment
- Bacillus and Francisella bacterial research
- Children's Physical and Motor Development
- Literary and Cultural Studies
Ministerio de Salud
2021-2024
Heterologous vaccination against coronavirus disease 2019 (COVID-19) provides a rational strategy to rapidly increase coverage in many regions of the world. Although data regarding messenger RNA (mRNA) and ChAdOx1 vaccine combinations are available, there is limited information about combination these platforms with other vaccines widely used developing countries, such as BBIBP-CorV Sputnik V. Here, we assess immunogenicity reactogenicity 15 1,314 participants. We evaluate immunoglobulin G...
Abstract The range of vaccines developed against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) provides a unique opportunity to study immunization across different platforms. In single-center cohort, we analyzed the humoral and cellular immune compartments following five disease 2019 (COVID-19) spanning three technologies (adenoviral, mRNA inactivated virus) administered in 16 combinations. For adenoviral inactivated-virus vaccines, heterologous combinations were generally...
<bold>Objetivo.</bold> Conocer la efectividad de vacunación contra SARS-CoV-2 para prevenir el desarrollo enfermedad y muerte por COVID-19 en Córdoba, Argentina, periodo enero-junio 2021. <bold>Métodos.</bold> Se llevó a cabo un estudio cohorte retrospectivo 1 139 458 residentes provincia Córdoba. construyeron modelos regresión logística múltiple que relacionaron con infección o COVID-19, considerando comorbilidades factores riesgo enfermedades crónicas ajustando sexo edad....
Monkeypox (Mpox) is a zoonotic disease caused by the monkeypox virus (MPXV). MPXV can be transmitted close contact with lesions, body fluids, respiratory droplets, and contaminated materials. A new pattern of spread among sexual networks has been recently described. The present work aimed to report epidemiological genomic characterization 2022 outbreak in central Argentina. total 113 scabs and/or lesion swab specimens were studied. infection was confirmed 46.0% studied patients, all whom...
Background The current COVID-19 pandemic has overloaded the diagnostic capacity of laboratories by gold standard method rRT-PCR. This disease a high spread rate and almost quarter infected individuals never develop symptoms. In this scenario, active surveillance is crucial to stop virus propagation. Methods Between July 2020 April 2021, 11,580 oropharyngeal swab samples collected in closed semi-closed institutions were processed for SARS-CoV-2 detection pools, implementing strategy first...
Abstract Background SARS-CoV-2 variants of concern (VOC) and interest (VOI) present mutations in reference to the original virus, being more transmissible. We implemented a rapid strategy for screening VOC/VOIs using real time RT-PCR performed monitoring surveillance our region. Methods consecutive real-time RT-PCRs detection relevant mutations/deletions Spike protein (TaqMan™ Mutation Panel, Applied Biosystems) were implemented. An algorithm was established 3941 RNA samples (Cts<30)...
Los estudios seroepidemiológicos permiten conocer la distribución indirecta de las enfermedades, detectando marcadores séricos inmunidad y demostrando infecciones no diagnosticadas en población general. El objetivo fue estimar seroprevalencia anticuerpos contra el SARS-CoV-2, Córdoba, Argentina, entre diciembre 2020 enero 2021, e identificar factores asociados a contagiosidad del virus. Se realizó un estudio observacional transversal, base poblacional, con 3.225 individuos mayores 2 años,...
ABSTRACT The emergence of COVID-19 in 2020 significantly enhanced the application wastewater monitoring for detecting SARS-CoV-2 circulation within communities. From October 2021 to 2022, we collected 406 samples weekly from Córdoba Central Pipeline Network (BG-WWTP) and six specific sewer manholes sanitary zones (SZs). Following WHO guidelines, processed detected RNA variants using real-time PCR. Monitoring at SZ level allowed development a viral activity flow map, pinpointing key areas...
Abstract Several vaccines have been found effective against COVID-19, usually administered in homologous regimens, with the same vaccine used for prime and boost doses. However, recent studies demonstrated improved protection via heterologous mix-and-match COVID-19 combinations, a direct comparison among these regimens is needed to identify best employment strategies. Here, we show single-cohort of changes humoral cellular immune compartments following five different spanning three...
Abstract Background The current COVID-19 pandemic has overloaded the diagnostic capacity of laboratories by gold standard method rRT-PCR. This disease a high spread rate and almost quarter infected individuals never develop symptoms. In this scenario, active surveillance is crucial to stop virus propagation. Methods Between July 2020 April 2021, 11580 oropharyngeal swab samples collected in closed semi-closed institutions were processed for SARS-CoV-2 detection pools, implementing strategy...