Lúcio Otávio Nunes

ORCID: 0000-0003-3707-2633
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Lipid Membrane Structure and Behavior
  • Biochemical and Structural Characterization
  • Chemical Synthesis and Analysis
  • Force Microscopy Techniques and Applications
  • Immune Response and Inflammation
  • Polydiacetylene-based materials and applications
  • Probiotics and Fermented Foods

Universidade Federal dos Vales do Jequitinhonha e Mucuri
2020-2025

Background/Objectives: This study investigates the structural and biophysical properties of wild-type antimicrobial peptide LyeTx I, isolated from venom spider Lycosa erythrognatha, its analog I-b, designed to enhance antibacterial activity, selectivity, membrane interactions by acetylation increased amphipathicty. Methods: To understand mechanisms behind these enhanced properties, comparative analyses structural, topological, biophysical, thermodynamic aspects between each phospholipid...

10.3390/antibiotics14010066 article EN cc-by Antibiotics 2025-01-10
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