A5032915212- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Catalytic Alkyne Reactions
- Catalytic C–H Functionalization Methods
- Crystallography and molecular interactions
- Sulfur-Based Synthesis Techniques
- Click Chemistry and Applications
- Asymmetric Synthesis and Catalysis
- Synthesis and Catalytic Reactions
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Reactions
- Chemical Synthesis and Analysis
- Asymmetric Hydrogenation and Catalysis
- Oxidative Organic Chemistry Reactions
- Fluorine in Organic Chemistry
- Carbon dioxide utilization in catalysis
- Catalytic Cross-Coupling Reactions
St. Xavier's College (Autonomous)
2014-2021
St Xavier’s College
2014-2021
Vellore Institute of Technology University
2016
Ruthenium-catalyzed simple, cascade and one-pot synthesis of cinnoline-fused diones has been carried out by the C–H activation phthalazinones/pyridazinones.
The <italic>Z</italic>-selectivity observed in imine and alkene motifs after 5-<italic>exo-dig</italic> cyclization of propargyl alcohol isothiocyanate is rare the literature this selectivity can be attributed to electronic steric factors motif respectively.
Abstract This study presents an efficient procedure for synthesis of 3,4,5‐trisubstituted 3 H ‐oxazol‐2‐ones and 3,4‐disubstituted (Z)‐oxazolidin‐2‐ones from substituted propargyl alcohols aryl/alkyl isocyanates in the presence LiO t Bu, a base, DMF, solvent. one‐step, low‐cost gram scale exhibits superior atom economy, good to excellent yields, enhanced substrate scope and, high functional group tolerance uses column chromatography‐free purifications. Further, product containing bromo...
Palladium( ii )acetate is found to be an efficient catalyst for the single-step conversion of secondary propargyl alcohols 1,3-diarylpropanone derivatives under mild basic conditions.
Abstract 5‐ exo ‐dig is a versatile Baldwin tool to predict and make useful heterocyclic compounds from nucleophiles electrophiles. In order aid this, novel metal‐free method proposed produce [1,3]‐oxathiole‐2‐thiones readily synthesized propargyl alcohols easily accessible carbon disulfide, where both secondary primary are compatible this methodology. This procedure simple, versatile, atom economy functional group tolerance resulting in moderate excellent yields. Finally, the process was...
Abstract The bond selectivity is caused by the traceless directing nature of hydroxyl group propargyl alcohol.
Abstract This report confirms that sodium tertiary‐pentoxide is a very effective base for the nucleophilic addition of acetylenes to aldehydes and ketones in 1,4‐dioxane at room temperature. These mild operationally simple procedures have been working well with variety aromatic heteroaromatic also equally aliphatic, ketones. A clean product secondary tertiary propargylic alcohols were obtained from 70–94% yield. process has explored bulk scale synthesis on selected molecules adapted column...