A5023495325- Reproductive tract infections research
- Cervical Cancer and HPV Research
- Genital Health and Disease
- BRCA gene mutations in cancer
- Psoriasis: Treatment and Pathogenesis
- Syphilis Diagnosis and Treatment
- HIV, Drug Use, Sexual Risk
- Cancer-related molecular mechanisms research
- Asthma and respiratory diseases
- Microbial infections and disease research
- Sex work and related issues
- Viral-associated cancers and disorders
- Hepatitis B Virus Studies
- Biomedical Ethics and Regulation
- Reproductive Health and Technologies
- Adolescent Sexual and Reproductive Health
- Medical and Health Sciences Research
- Family and Disability Support Research
- Dermatology and Skin Diseases
- Behavioral and Psychological Studies
- Pharmacogenetics and Drug Metabolism
- Estrogen and related hormone effects
- Bacterial Infections and Vaccines
- Patient Safety and Medication Errors
- Hydrogels: synthesis, properties, applications
Odense University Hospital
2025
University of Southern Denmark
2025
University of Oslo
2012-2024
Norwegian Institute of Public Health
1998-2024
NYU Langone Health
2018-2021
Icahn School of Medicine at Mount Sinai
2020
Oslo University Hospital
2005-2018
New York University
2016-2018
Norwegian Veterinary Institute
2018
University of Pennsylvania
2014
Journal Article Is the prevalence of psoriasis increasing? A 30‐year follow‐up a population‐based cohort Get access K. Danielsen, Danielsen Department Dermatology, Neurology and Orthopaedic Clinic, University Hospital North Norway, Tromsø, NorwayDepartment Community Medicine, Faculty Health Sciences, Norway Kjersti Danielsen. E‐mail: kjersti.danielsen@unn.no Search for other works by this author on: Oxford Academic Google Scholar A.O. Olsen, Olsen Rheumatology, Dermatology Infectious...
Monozygotic (MZ) twins do not show complete concordance for many complex diseases; example, discordance rates autoimmune diseases are 20%–80%. MZ indicates a role epigenetic or environmental factors in disease. We used discordant psoriasis to search genome-wide differences DNA methylation and gene expression CD4+ CD8+ cells using Illumina's HumanMethylation27 HT-12 assays, respectively. Analysis of these data revealed no differentially methylated expressed genes between co-twins when...
Mycoplasma genitalium (MG) causes urethritis and cervicitis, potentially causing reproductive complications. Resistance in MG to first-line (azithromycin) second-line (moxifloxacin) treatment has increased. We examined the clinical analytical performance of new Conformité Européene (CE)/in vitro diagnostics (IVD) Aptima assay (CE/IVD AMG; Hologic); prevalence MG, Chlamydia trachomatis (CT) Neisseria gonorrhoeae (NG); resistance azithromycin moxifloxacin Denmark, Norway Sweden 2016.From...
Gonorrhoea cases increased steeply in women aged 20 to 24 years across 15 EU/EEA countries July December 2022 and January June 2023 with, respectively, 73% 89% more reported than expected, based on historical data from 2015 2019. Smaller increases among men due heterosexual transmission were observed nine countries. Interventions raise awareness young people about sexually transmitted infection risks are needed, emphasising the benefit of safe sexual practices testing.
Gonorrhea may become untreatable, and new treatment options are essential. Verified resistance to spectinomycin is exceedingly rare. However, we describe a high-level spectinomycin-resistant (MIC, >1,024 μg/ml) Neisseria gonorrhoeae strain from Norway with novel mechanism. The determinant was deletion of codon 27 (valine) K28E alteration in the ribosomal protein 5S. traditional gene (16S rRNA) wild type. Despite this rare finding, available for ceftriaxone-resistant urogenital gonorrhea...
Questions remain concerning to what extent age and sex may modify the suggested association between psoriasis metabolic syndrome in general population.To investigate within a large population-based cohort by sex.A cross-sectional study including 10 521 participants aged 30-79 years from Tromsø Study was performed; 1137 reported lifetime of mainly mild character. The new harmonized definition used multivariable logistic regression analysis.There uniformly higher prevalence men women with...
New cases of gonorrhoea (Neisseria gonorrhoeae) and chlamydia (Chlamydia trachomatis) infections have been steadily increasing in Scandinavian countries over the last decade. There is a particular urgency reducing new as isolation multiple drug resistant strains becoming more frequent. The aim this study was to determine prevalence sites infection common sexually transmissible (STIs) men who sex with (MSM).We performed retrospective analysis three major STIs, gonorrhoea, Mycoplasma...
Abstract Objectives Mycoplasma genitalium is a common cause of non‐gonococcal urethritis ( NGU ) in Western Europe, but not routinely tested for all clinics. A high prevalence macrolide‐resistant M. has been reported. An easy to use test that can predict likely macrolide treatment failure potentially very valuable. We report the development rapid and reliable real‐time PCR ‐assay which detects relevant resistance loci 23S rRNA gene. Methods ‐positive clinical samples were collected between...
Piscine orthoreovirus (PRV-1) causes heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). Recently, a novel PRV (formerly PRV-Om, here called PRV-3), was found rainbow trout (Oncorhynchus mykiss) with HSMI-like disease. is considered to be an emerging pathogen salmonids. In this study, molecular antigenic characterization of PRV-3 performed. Erythrocytes are the main target cells for PRV, blood samples that were collected from experimentally challenged fish...
Abstract The association between certain human papillomaviruses (HPV) and cervical intraepithelial neoplasia (CIN) is well documented, but there uncertainty about the strength of role co‐factors unclear. This population‐based case‐control study in Norwegian women 20–44 years age included 103 cases with histologically confirmed CIN II–III 234 age‐matched randomly selected controls. Cytological specimens from cervix were analyzed using polymerase chain reaction (PCR). In all, 91% 15% controls...
Abstract To investigate whether anthropometric indices as body height, body‐mass index (BMI) and body‐surface area (BSA) have any influence on the risk of cutaneous malignant melanoma (CMM), we analyzed height weight data from a Norwegian screening survey running between 1963 1975 comprising 1.3 million individuals followed for 14 to 26 years. Among females, CMM was diagnosed in 2814 incident cases, while number among males 2144 during 22,988,345 person‐years follow‐up. With adjustment age,...
In 2009, both Norway and Denmark initiated routine quadrivalent human papillomavirus vaccination (qHPV) for 12-year-old girls; however, also introduced free-of-charge multi-cohort older age groups in 2008. We aim to describe trends genital warts (GWs) incidence rates (IRs) among men women qHPV vaccine coverage 2006–2015. linked multiple national health registries via personal identifiers access data on GWs aged 12–35 years residing calculated age-specific age-standardized IRs, IR before...
This study presents the nationwide epidemiology of Neisseria gonorrhoeae, using whole-genome sequencing all culture-positive cases, which comprise roughly 40 % cases gonorrhea reported in Norway from 2016 to 2017. Isolates were assigned sequence types and Bayesian analysis clusters variation genes coding for antibiotic resistance was linked phenotypic data. The also included isolates taken same patients different anatomical sites at one or more time points. Comparing these allows observation...
To study the combined effect of smoking and human papillomavirus (HPV) type 16 infection in high-grade cervical intraepithelial neoplasia, we analyzed data from a Norwegian population-based case-control including 90 patients 216 controls, 20-44 years age. We assessed HPV-16 status both by polymerase chain reaction detecting virus DNA enzyme-linked immunosorbent assay antibodies against capsid. Smoking was associated with neoplasia grade II-III HPV-16-positive individuals. Using jointly...
Several recent studies have reported different associations between HLA specificities and human papillomavirus (HPV)-associated disease of the cervix. We report distribution DQA1 DQB1 genes HPV infection in a population-based case–control study including 92 patients with histologically verified cervical intraepithelial neoplasia grade II-III (CIN II-III) (thus moderate severe dysplasia carcinoma situ) 225 control subjects. found an overrepresentation DQA1*0102-DQB1*0602 haplotype among...
Few evidence-based practices, defined as the use of empirically supported research and clinical expertise for children with autism, have been successfully implemented sustained in schools. This study examined perspectives school personnel ( n = 39) on implementing a social engagement intervention autism. Semi-structured interviews, informed by Domitrovich et al. (2008) framework, were conducted. Participants asked about (1) factors that affect general implementation (2) their specific...
Objective: Several surgical approaches are being used in the reconstruction of long-gap esophageal atresia. We investigated which methods Nordic countries and postoperative complications that occurred first year life. Methods: This study is a retrospective multicenter study, where medical records on children with atresia Gross type C or D born period from 1 January 2000 to May 2017 were reviewed. Results: Forty-four patients included this forty-three one D. Thirty-six statistical analysis....
In this study we assessed the quality of health care for infertile patients as expressed by themselves. The implementation existing structured plan infertility investigation and treatment was also reviewed. DESIGN AND DATA: sample consisted all 361 women registered with an diagnosis during 1982 at Rikshospitalet. Their medical records were reviewed in 1988. process outcome it appeared analyzed each individual patient. A questionnaire distributed to 1988 72.6% responded. questions included...
OBJECTIVES: To assess if seropositivity to human papillomavirus type 16 capsids is a better marker of sexual history than the presence HPV DNA. STUDY DESIGN: A population based age stratified random sample 234 Norwegian women (mean 32.8 years, range 20-44) was examined for serum antibodies, cervical DNA, cytology and in relation behaviour. RESULTS: Neither nor at first intercourse associated with antibodies. Adjusted ORs 4-5; 6-10 > 10 versus 0-1 lifetime partners, were 13.1 (95% CI...
Background Psoriasis is a chronic T-cell-mediated immunological skin disease. The occurrence of the disease appears to differ with geography and ethnicity. There need for epidemiological data obtained from defined population-based studies, sex-specific differences observed in natural history require more attention. Objectives To describe risk psoriasis Norway by age sex. Patients/methods A health survey was conducted 1998 Norwegian twins aged 19–31 years. present study based upon...
Counts of nuclei in enzyme digested endosperms barley cultivar Bomi show that the final number cells, 170000, is reached between 18 and 21d after anthesis. Based on cell profiles transverse mid-grain sections, starchy endosperm cells divide up to day 14. Thereafter, proliferation restricted aleurone layer.
In the present study, leukocyte DNA from 143 patients with familial clustering of breast and/or ovarian cancer and tumour 96 carcinomas were screened for base mutations in estrogen receptor gene (ESR). Three a family history carrying Gly160Cys germline substitution. This alteration was also detected eight (four females four males) 729 controls (366 female, 363 males), indicating that substitution probably represents polymorphism. However, 229 female whom known, one two who had sister variant...