A5058368740- Extracellular vesicles in disease
- MicroRNA in disease regulation
- Marine Invertebrate Physiology and Ecology
- Advanced Fluorescence Microscopy Techniques
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- Sperm and Testicular Function
- Cell Image Analysis Techniques
- Mesenchymal stem cell research
- Optical Imaging and Spectroscopy Techniques
- Wound Healing and Treatments
- Corneal Surgery and Treatments
- Advanced Electron Microscopy Techniques and Applications
- Cancer Research and Treatments
- Photoacoustic and Ultrasonic Imaging
- Molecular Biology Techniques and Applications
- Autism Spectrum Disorder Research
- RNA Interference and Gene Delivery
- Infant Development and Preterm Care
- Family and Disability Support Research
Bushehr University of Medical Sciences
2021-2024
Biotechnology Research Center
2021
Background and Aim . Down syndrome (DS) is the most common reason for disabilities caused by genetic disorders. Due to special nature of this disease needs children with syndrome, they are required receive their families’ support. Therefore, recognition problems also alternatives resolving them promoting life quality very useful. Also, since limited qualitative studies have been conducted, it seems necessary design a study. Method This study was conducted content analysis method through...
Regenerative effects of sea anemone-derived exosomes on human foreskin fibroblasts (HFFs) were investigated. Water-based extracts from regenerating Aulactinia stella tissue collected at various time points, and extracted after inducing wounds. Both the extract tested HFF for proliferation in vitro wound healing. In silico analysis explored protein–protein docking between regenerative exosome proteins receptors. The MTT (3-(4,5-dimethylthiazol-2yl)-2,5 diphenyltetrazolium bromide assay...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and rapidly spread worldwide.Since then, scientists have searched to find an effective treatment for disease .In this regard, several antiviral drugs are currently undergoing clinical trial studies evaluate their safety efficacy the of COVID-19.Some these been designed based on fact that SARS-CoV-2 is a positive-sense single-stranded RNA virus previous showed anti-RNA virus, single strand inhibiting...
Abstract Background One of the main cause male infertility is non-obstructive azoospermia, which not manageable medically. The first aim current research was to show effect extracellular vesicle-contained conditioned media (CM) instead mesenchymal stromal/stem cells (MSCs) for treatment azoospermia. In next step, we aimed study differentiation potential MSCs into spermatocytes after injection in mice seminiferous tubules. This has provided an applied busulfan-induced azoospermia using...
Abstract One of the main cause male infertility is non-obstructive azoospermia, which not manageable medically. The first aim current research was to show effect extracellular vesicle-contained conditioned media (CM) instead mesenchymal stromal/stem cells (MSCs) for treatment azoospermia. In next step, we aimed study differentiation potential MSCs into spermatocytes after injection in mice seminiferous tubules. This has provided an applied busulfan-induced azoospermia using adipose...
Abstract This study evaluated the possible regenerative effects of proliferating sea anemone cells-derived exosomes on human foreskin fibroblasts (HFF). Water-based extracts from Aulactinia stella tissue 48 h after regeneration was collected. The anemone, species were wounded middle column and extracted 0 h, 24 72 96 wound induction. extract separately analyzed HFF using MTT for proliferation in vitro healing cell migration test. Additionally, an in-silico analysis performed to investigate...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 is rapidly spreading worldwide. Scientists are searching to find an effective treatment for disease (COVID-19). Several antiviral drugs currently undergoing clinical trial studies evaluate their safety and efficacy the of COVID-19. SARS-CoV-2 a positive-sense single-stranded RNA virus. Previous showed anti-RNA virus, single strand inhibiting antisense RNAs (asRNAs), on silencing virus replication,...
FACT is a developed technique using no acrylamide for clearing tissues. As the lipid removal normally harmful process and it causes loss of biological molecules such as proteins on other hand crucial transparency efficient antibody staining throughout whole tissue especially microscopy imaging, suitable since makes chemical bonding membrane intracellular with extracellular matrix creating massive 3D structural support to fortify during processing. Compared acrylamide-based techniques,...
Abstract Free of Acrylamide Sodium Fast Free-of-Acrylamide Clearing Tissue (FACT) is a developed technique using no acrylamide for clearing tissues. As the lipid removal normally harmful process and it causes loss biological molecules such as proteins on other hand crucial transparency efficient antibody staining throughout whole tissue especially microscopy imaging, FACT suitable since makes chemical bonding membrane intracellular with extracellular matrix creating massive three-dimensional...