A5065369223- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hemodynamic Monitoring and Therapy
- Pneumonia and Respiratory Infections
- Ultrasound in Clinical Applications
- Emergency and Acute Care Studies
- Respiratory Support and Mechanisms
- Acute Myocardial Infarction Research
- Nosocomial Infections in ICU
- Heart Failure Treatment and Management
- COVID-19 Clinical Research Studies
- Complementary and Alternative Medicine Studies
- Heart Rate Variability and Autonomic Control
- Tuberculosis Research and Epidemiology
- Long-Term Effects of COVID-19
- Healthcare and Venom Research
- Infectious Encephalopathies and Encephalitis
- Blood Pressure and Hypertension Studies
- Gastroesophageal reflux and treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Potassium and Related Disorders
- Cardiac electrophysiology and arrhythmias
- Patient Satisfaction in Healthcare
- Bee Products Chemical Analysis
- Atrial Fibrillation Management and Outcomes
Hospital Fatuma Bourguiba Monastir
2017-2025
University of Monastir
2015-2025
Hôpital Sahloul
2020
Zinc supplementation has been considered a potential therapy for coronavirus disease 2019 (COVID-19). We aimed to examine zinc efficacy in adult patients with COVID-19 infection.We conducted prospective, randomized, double-blind, placebo-controlled multicenter trial. Patients who were tested positive without end-organ failure randomized oral (n = 231) or matching placebo 239) 15 days. The primary combined outcome was death due intensive care unit (ICU) admission ≤30 days after randomization....
This study aims to evaluate the effectiveness and tolerability of a phytotherapeutic topical gel (Douloff®) compared oral paracetamol for acute pain resulting from minor limb soft tissue injuries. A prospective, multicenter, randomized, double-blind conducted over 13 months in three EDs. Patients aged 18 years older, with injuries, were randomized into Douloff® (n = 765) 750) groups. The primary outcome was resolution rate (reduction at least 50% intensity, measured by numeric rating scale...
Abstract Objectives We aim to determine the benefit of two different doses magnesium sulfate (MgSO 4 ) compared placebo in rate control rapid atrial fibrillation ( AF managed emergency department ED ). Methods undertook a randomized, controlled, double‐blind clinical trial three university hospital s between August 2009 and December 2014. Patients > 18 years with (>120 beats/min) were enrolled randomized 9 g intravenous MgSO (high‐dose group, n = 153), 4.5 (low‐dose 148), or serum...
Introduction: Duration of antibiotic treatment in acute exacerbation COPD (AECOPD) is most commonly based on expert opinion. Typical administration periods range from 5 to 7 days. A 2-day course with levofloxacin was not previously assessed. We performed a randomized clinical trial evaluate the efficacy versus 7-day patients AECOPD. Methods and analysis: Patients AECOPD were receive for 2 days placebo ( n = 155) or 155). All received common dose intravenous prednisone daily The primary...
Introduction: Identifying heart failure (HF) in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) can be challenging. Lung ultrasound sonography (LUS) B-lines quantification has recently gained a large place the diagnosis HF, but its diagnostic performance AECOPD remains poorly studied. Purpose: This study aimed to assess contribution LUS score (LUS score) HF patients. Patients and methods: is prospective cross-sectional multicenter cohort including patients admitted...
Objectives: To evaluate the efficacy and safety of early administration low-dose intranasal ketamine on reducing need for opioid nonopioid analgesic agents in emergency department (ED) patients with acute moderate to severe limbs’ trauma pain. Patients Methods: This is a double-blind, randomized, prospective, controlled study conducted ED. The included were randomly assigned pulverization or placebo. Protocol treatment was given at triage. primary outcome opioids during ED stay. Secondary...
Abstract Background Ultrasonographic B-lines have recently emerged as a bedside imaging tool for the differential diagnosis of acute dyspnea in Emergency Department (ED). However, despite its simplicity, LUS has not fully penetrated emergency department. This study aimed to assess accuracy and reproducibility ultrasonographic performed by medicine (EM) residents congestive heart failure (CHF) patients admitted ED dyspnea. Patients methods is cross-sectional prospective conducted between...
Aim of the study The diagnosis heart failure in emergency department (ED) is challenging. aim this was to evaluate systolic time intervals (STIs) using phonoelectrocardiography for (HF) ED patients with undifferentiated dyspnea. Methods A total 855 dyspnea and suspected HF were prospectively enrolled. They underwent echocardiographic measurements left ventricular ejection fraction (LVEF), B-type natriuretic peptide (BNP) testing computerised assess STIs including electromechanical activation...
Abstract Objectives Nonsteroidal anti‐inflammatory drugs (NSAIDs) and acetaminophen (also called paracetamol) are the most frequent analgesics used to relieve posttrauma pain in emergency department (ED). However, utility of combining both treatments is still controversial. We sought explore benefits an NSAID with compared alone, or treatment posttraumatic extremity after discharge from ED. Methods This a prospective, randomized controlled trial, carried out single ED March 2017 November...
<b><i>Background:</i></b> Digoxin is a substrate of P-glycoprotein (P-gp) and organic anion transporting polypeptide transporters that are encoded by <i>ABCB1</i> <i>SLCO1B3</i> genes. Genetic polymorphisms in both genes may explain inter-individual variability serum digoxin concentration (SDC). This study evaluates the possible effect most common on SDC after single oral dose Tunisian atrial fibrillation (AF) patients....
Little is known about the pattern and appropriateness of antibiotic prescriptions in patients with acute respiratory tract infections (ARTIs).Describe antibiotics used to treat ARTIs Tunisian primary care offices emergency departments (EDs), assess their use.It was a prospective multicenter cross-sectional observational clinical study conducted at 63 6 EDS during period 8 months. Appropriateness prescription evaluated by trained physicians using medication index (MAI). The MAI ratings...
Background A number of factors may offset the cardioprotective effects glucose‐insulin‐potassium (GIK) on outcome patients with acute coronary syndrome, such as hyperglycemia induced by this cocktail infusion. We performed a study to evaluate effect intensive insulin therapy in association GIK 1‐year hospitalized for syndrome. Methods and Results In randomized prospective controlled trial we included 772 non–ST‐segment elevation Patients were into 3 groups: GIKI 2 group, who received 24...
Short-acting β2 -agonists are the mainstay of treatment patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD) in emergency department (ED). It is still unclear whether addition short-acting anticholinergics clinically more effective care compared to alone hypercapnic AECOPD.The objective was evaluate combining ipratropium bromide (IB) terbutaline reduces hospital and intensive unit (ICU) admission rates AECOPD patients.In this double-blind controlled trial, who were...
Abstract Background Emergency medicine is particularly well suited to simulation training. However, evidence for the efficacy of simulation-based medical training remains limited especially manage high-risk cases such as acute asthma. Objective The objective our study was compare performance high-fidelity (HFS) and interactive video-case challenge-based (IVC) final-year students in management Methods This a prospective randomized controlled conducted at emergency department (ED) Monastir...
Introduction Duration of antibiotic treatment in acute exacerbation COPD (AECOPD) is most commonly based on expert opinion. Biomarker guided strategy increasingly recommended to limit unnecessary use. We performed a randomized controlled study evaluate the efficacy 2-day versus C-reactive protein (CRP)-guided with levofloxacin patients AECOPD. Methods Patients AECOPD were receive oral daily for 7 days unless serum CRP level decreased by at least 50% from baseline value or two days;...
Abstract Background Chest pain remains one of the most challenging serious complaints in emergency department (ED). A prompt and accurate risk stratification tool for chest patients is paramount to help physcian effectively progrnosticate outcomes. HEART score considered best scores stratification. However, validation studies were not performed populations different from those included original one. Objective To validate as a prognostication tool, among Tunisian ED with undifferentiated...
Renal colic (RC) is a common urologic emergency often leading to significant pain and recurrent hospital visits. This study aimed compare the efficacy safety of piroxicam versus paracetamol in preventing recurrence readmission patients treated for RC discharged from department (ED).
<sec> <title>BACKGROUND</title> Control of hypertension has shown a decrease in blood pressure compared to usual care </sec> <title>OBJECTIVE</title> The Horoscope trial aimed assess the efficacy home (BP) telemonitoring (TLM) controlling BP reduction hypertensive patients with care. <title>METHODS</title> This is multi-center, prospective randomized, parallel-group comparing TLM during period 6 months hypertension. <title>RESULTS</title> We included 525 randomly assigned 1-1 ratio (TLM...
COPD is a major public health problem due to its high morbidity and mortality. The evolution of marked by the occurrence acute exacerbations (AECOPD). One causes AECOPD non-adherence treatment. Telemedicine an accessible educational tool that can help physicians provide continuous, support monitoring for patients with COPD.