A5013397653- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Coronary Interventions and Diagnostics
- Fluid Dynamics and Turbulent Flows
- Cardiac Imaging and Diagnostics
- Mechanical Circulatory Support Devices
- Congenital heart defects research
- Venous Thromboembolism Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Hydraulic and Pneumatic Systems
- Pulmonary Hypertension Research and Treatments
- Wind and Air Flow Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Orthopaedic implants and arthroplasty
- Cardiac pacing and defibrillation studies
- Coronary Artery Anomalies
- Vascular anomalies and interventions
- Cardiomyopathy and Myosin Studies
- Fluid Dynamics and Vibration Analysis
- Particle Dynamics in Fluid Flows
Georgia Institute of Technology
2009-2025
Emory University
2005-2025
The Wallace H. Coulter Department of Biomedical Engineering
2006-2025
Colorado State University
2010-2024
The Ohio State University
2016-2024
System Dynamics International (United States)
2024
Piedmont Atlanta Hospital
2021-2024
Children's Healthcare of Atlanta
2024
Nationwide Children's Hospital
2021
Texas Children's Hospital
2021
We present comprehensive particle image velocimetry measurements and direct numerical simulation (DNS) of physiological, pulsatile flow through a clinical quality bileaflet mechanical heart valve mounted in an idealized axisymmetric aorta geometry with sudden expansion modeling the aortic sinus region. Instantaneous ensemble-averaged velocity as well associated statistics leaflet kinematics are reported analyzed tandem to elucidate structure vorticity fields ensuing flow-structure...
Little is known about the impact of total cavopulmonary connection (TCPC) on resting and exercise hemodynamics in a single ventricle (SV) circulation. The aim this study was to elucidate mechanism using lumped parameter model SV Pulmonary vascular resistance (1.96+/-0.80 WU) systemic resistances (18.4+/-7.2 were obtained from catheterization data 40 patients with TCPC. TCPC (0.39+/-0.26 established computational fluid dynamic simulations conducted anatomically accurate three-dimensional...
The hemocompatibility of superhemophobic surfaces is investigated and compared with that hemophobic hemophilic surfaces. This analysis indicates only those a robust Cassie–Baxter state display significantly lower platelet adhesion activation. It envisioned the understanding gained through this work will lead to fabrication improved hemocompatible, medical implants. As service our authors readers, journal provides supporting information supplied by authors. Such materials are peer reviewed...
Abstract Vascular cell overgrowth and lumen size reduction in pulmonary vein stenosis (PVS) can result elevated PV pressure, hypertension, cardiac failure, death. Administration of chemotherapies such as rapamycin have shown promise by inhibiting the vascular proliferation; yet clinical success is limited due to complications restenosis off‐target effects. The lack vitro models recapitulate complex pathophysiology PVS has hindered identification disease mechanisms therapies. This study...
A new technique is presented for interpolating between grey-scale images in a medical data set. Registration neighboring slices achieved with modified control grid interpolation algorithm that selectively accepts displacement field updates manner optimized performance. cubic interpolator then applied to pixel intensities correlated by the fields. Special considerations are made efficiency, quality, and compression implementation of algorithm. Experimental results show method achieves good...
Presented here is a radically novel approach to reduce concentration polarization and, potentially, also fouling by colloids present in aqueous feeds: magnetically responsive micromixing membranes. Hydrophilic polymer chains, poly(2-hydroxyethyl methacrylate) (PHEMA), were grafted via controlled surface-initiated atom transfer radical polymerization (SI-ATRP) on the surface of polyamide composite nanofiltration (NF) membranes and then end-capped with superparamagnetic iron oxide magnetite...
Shear stress on blood cells and platelets transported in a turbulent flow dictates the fate biological activity of these cells. We present theoretical link between energy dissipation flows to shear that experience show for case physiological flow: (a) Newtonian assumption is valid, (b) eddies are universal most complex problems, (c) distribution possibly universal. Further we resolve long standing inconsistency hemolysis laminar using framework. This work demonstrates as opposed bulk or...
In this review, we critically examine the progress made in characterizing hemocompatibility of super-repellent surfaces and identify potential challenges opportunities for future research.