A5038158291- Retinal Diseases and Treatments
- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Ocular Oncology and Treatments
- Vascular Malformations Diagnosis and Treatment
- Toxoplasma gondii Research Studies
- Ocular Surface and Contact Lens
- Drug-Induced Ocular Toxicity
- Ocular Infections and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Corneal Surgery and Treatments
- Ocular Disorders and Treatments
- Research on Leishmaniasis Studies
- Retinopathy of Prematurity Studies
- Occupational Health and Burnout
- Hernia repair and management
- Bartonella species infections research
- Moyamoya disease diagnosis and treatment
- Esophageal and GI Pathology
- Maternal Mental Health During Pregnancy and Postpartum
Universidade Federal de São Paulo
2015-2024
Retina Clinic
2016-2024
Universidade Nova de Lisboa
2023-2024
Centro Hospitalar de Trás os Montes e Alto Douro
2023-2024
Center for Global Health
2024
Hospital da Senhora da Oliveira Guimarães
2022-2023
Hospital Santo António dos Capuchos
2023
Hospital de Santo António
2023
Centro Hospitalar de Lisboa Ocidental
2023
Instituto de Biologia Molecular e Celular
2022
<b><i>Introduction:</i></b> There are few real-life studies on the intravitreal 0.7-mg dexamethasone implant for treatment of diabetic macular edema (DME) conducted in Latin America. We aimed to assess effectiveness and safety this clinical practice. <b><i>Methods:</i></b> Twenty-seven centers from Brazil one Argentina provided information patients with DME treated Ozurdex. The efficacy outcome variables were best-corrected visual acuity (BCVA)...
Diabetic macular edema is the leading cause of blindness in young adults developed countries. Beyond metabolic control, several therapies have been studied such as laser treatment and intravitreal injections corticosteroids or anti-vascular endothelial growth factor drugs. In terms public health long-term with current available drugs very expensive new same better effect should be investigated. This study sought to evaluate efficacy safety ziv-aflibercept for diabetic edema.Seven consecutive...
To determine the effects of lens status on success rate primary pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment using either perfluoropropane gas (C3F8) or silicone oil (SO) tamponade.A retrospective chart analysis was made 97 eyes from 92 patients with no proliferative vitreoretinopathy that were treated 23-gauge PPV. Eyes included in this phakic (n = 28), pseudophakic 41), subject to simultaneous phacoemulsification, intraocular implantation, and PPV during repair 28)....
Abstract Background The purpose of the current study is to report anatomical and functional results off-label human amniotic membrane graft as primary intervention repair large giant macular holes in reoperations when wide internal limiting peeling was unsuccessful. Methods Retrospective chart review carried out five different centers identify all cases that had undergone for treatment or failed (MH). Data collected included age, gender, other concomitant diagnosis, symptoms duration, lens...
A insônia crônica é um fator relevante na depressão resistente ao tratamento (TRD), influenciando a eficácia das intervenções antidepressivas e contribuindo para persistência dos sintomas. Embora tradicionalmente considerada sintoma da depressão, evidências recentes indicam que pode desempenhar papel causal resistência tratamento, afetando mecanismos neurobiológicos como disfunção do eixo hipotálamo-hipófise-adrenal, neuroinflamação alterações plasticidade cerebral. Estratégias terapêuticas,...
Purpose To analyse the pooled safety data of intravitreal ziv-aflibercept (IVZ) therapy for various retinal conditions. Methods This was a retrospective, observational study which included patients from 14 participating centres who received IVZ. The medical records IVZ March 2015 through October 2017 were evaluated. Patient demographics and ocular details compiled. Ocular systemic adverse events that occurred within 1 month injections recorded defined as either procedure-related or...
The results of a patient with exudative age-related macular degeneration who received an intravitreal injection ziv-aflibercept (Zaltrap; Sanofi-Aventis, Paris, France) in the right eye are described. A complete ocular examination as well color fundus photography, optical coherence tomography, fluorescein angiography, microperimetry, full-field electroretinography, and multifocal electroretinography were performed repeated 1 month later. experienced subjective objective improvement visual...
Abstract Background Leishmania infantum is endemic in the Mediterranean region, presenting mostly as visceral leishmaniasis (VL). In Portugal, reporting of VL cases to public health authorities mandatory, but significant underreporting likely. This study aimed describe epidemiological and clinical aspects diagnosed hospitals Portuguese National Health Service (NHS), between 2010 2020. Methods Collaboration was requested every hospital NHS Mainland Portugal. Cases were screened through a...
We retrospectively evaluated a heavy silicone oil (HSO) as long-term intraocular endotamponade agent to treat complicated RD by inferior PVR in 25 eyes of patients. Patients underwent PPV and injection Oxane HD an internal tamponade agent. A comparison preoperative postoperative BCVA at month 1, 6, last visit was made the group which HSO removed not removed. Statistical calculations were performed using Wilcoxon test. The from 11 patients after mean 26.55 ± 21.38 months. remained inside...
We examined the structure-function relationship between two perimetric tests, frequency doubling technology (FDT) matrix and standard automated perimetry (SAP), optical coherence tomography (OCT) devices (time-domain spectral-domain).This cross-sectional study included 97 eyes from 29 healthy individuals, 68 individuals with early, moderate, or advanced primary open-angle glaucoma. The correlations overall sectorial parameters of retinal nerve fiber layer thickness (RNFL) measured Stratus...
To compare infusion and extrusion fluid volumes with three 25-gauge vitrectomy systems.The aspiration rates of systems from Alcon (Fort Worth, TX, USA), Bausch & Lomb (St Louis, MO, the Dutch Ophthalmic Research Centre (DORC, Zuidland, Netherlands) were measured in vitro using balanced saline solution different heights (40, 60, 80, 100, 120 cm) bottle, cutter velocities (800, 1100, 1500 cuts/ min) powers (100, 200, 300, 400, 500 mmHg).The flow differed among (p < 0.001 for all comparisons...
To evaluate the 6-month safety and efficacy of ziv-aflibercept intravitreal injections for treating exudative age-related macular degeneration.Fifteen patients with unilateral degeneration were enrolled. The best-corrected visual acuity was measured spectral domain optical coherence tomography performed at baseline monthly. Full-field electroretinography multifocal obtained 4, 13, 26 weeks after first injection. All received three monthly (1.25 mg) followed by as-needed treatment.Between...
To review long time treatment results in patients with small or medium sized choroidal melanoma who underwent surgical tumor endoresection as a primary when plaque radiotherapy was unable and declined enucleation.Patients were evaluated for best corrected visual acuity (BCVA), biomicroscopy, indirect ophthalmoscopy, retinography ultrasound well the usual systemic workup. Study inclusion required absence of scleral invasion metastasis an anterior margin not exceeding pars plana ciliary body....
BACKGROUND AND OBJECTIVE: To study the safety and efficacy of intravitreal injections ziv-aflibercept (IVI-ZA) (Zaltrap; Sanofi-Aventis Regeneron Pharmaceuticals, Tarrytown, NY) during a period 48 weeks in patients with diabetic macular edema (DME). PATIENTS METHODS: Seven consecutive DME were enrolled submitted to 12 IVI-ZA 4-week interval. The parameters included changes full-field electroretinogram (ERG) systemic or ocular complications, mean change from baseline best-corrected visual...
To establish the prevalence and risk factors for intravitreal dexamethasone implant migration into anterior chamber in eyes with macular edema.This was a multicenter, retrospective, observational chart review of data that included patients edema who had been treated at least one injection. Patients incomplete information during follow-up period were excluded.The 468 patients, considering number injections, 1.6%, significant associations between cataract surgery (P = 0.043) intraocular lens...
To evaluate the ultrasound biomicroscopy (UBM) images of recent postoperative 23-gauge vitrectomy using single- and 2-step techniques.Twelve consecutive eyes were randomized submitted to sutureless transconjunctival surgery divided in 2 groups: 1) a beveled trocar insert microcannula (single step) 2) stiletto blade perform first tunnel incision then (2 steps). All patients underwent 3-port with straight angled 20 degrees 30 degrees. Ultrasound examination was performed after 8 days 10 locate...
Susac's syndrome (SuS) is an uncommon disease characterized by retinal microangiopathy that may be assessed more accurately with optical coherence tomography angiography (OCTA), a new imaging technique which provides microvasculature map. The purpose of this case report to describe the multimodal findings SuS correlating OCTA functional tests.Retrospective review one clinical and evidence SuS. Color fundus photograph, fluorescein (FA), OCTA, microperimetry (MP) visual field (VF) tests were...
To evaluate the 52-week safety and efficacy of intravitreal ziv-aflibercept in patients with neovascular age-related macular degeneration.All received three monthly injections 0.05 mL (1.25 mg) followed by a pro re nata regimen. The best-corrected visual acuity spectral domain optical coherence tomography were obtained at baseline monthly. Full-field multifocal electroretinograms 4, 13, 26, 52 weeks. For some full-field electroretinography parameters, we calculated differences between weeks...
Purpose . To evaluate the best-corrected visual acuity (BCVA), central retinal thickness (CRT), and number of dexamethasone implants needed to treat cystoid macular edema (CME) from various etiologies over 12 months in vitrectomized nonvitrectomized eyes. Methods This multicenter retrospective cohort study included 112 patients with CME secondary diseases treated pro re nata (PRN) a 0.7 mg intravitreal implant for months. The BCVA, CRT, adverse events, safety data, were recorded. Results...
To determine the long-term anatomic outcomes and surgical complications of pars plana vitrectomy (PPV) 4-point Gore-Tex-sutured Akreos AO60 intraocular lens (IOL) scleral fixation. Retrospective, multicenter, multisurgeon case series. Ninety-seven patients in tertiary eye care centers. The underwent PPV fixation IOL using Gore-Tex CV-8 sutures between January 2015 April 2020. inclusion criteria were aphakia, no capsular support, a minimal 1 year follow-up. Uncorrected visual acuity (VA),...
Introduction Recurrent hospitalizations for worsening heart failure (WHF) represent a major global public health concern, resulting in significant individual morbimortality and socioeconomic costs. This real-life study aimed to determine the rate predictors of readmission WHF cohort outpatients with chronic (CHF) followed clinic (HFC) at university hospital. Methods We conducted longitudinal, observational, retrospective all consecutive CHF patients seen HFC São Francisco Xavier Hospital,...
UNO, FAUSTO MD; MALERBI, FERNANDO MAIA, MAURÍCIO FARAH, MICHEL EID ANDRÉ MAGALHÃES, OCTAVIANO JR MD Author Information