Ramalingam Karthik Raja

ORCID: 0000-0003-3782-046X
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About
Contact & Profiles
Research Areas
  • Research on Leishmaniasis Studies
  • Nanoparticles: synthesis and applications
  • Entomopathogenic Microorganisms in Pest Control
  • Insect Resistance and Genetics
  • Trypanosoma species research and implications
  • Insect Pest Control Strategies
  • Aquaculture disease management and microbiota
  • Insect and Arachnid Ecology and Behavior
  • Insect and Pesticide Research
  • Moringa oleifera research and applications
  • Nematode management and characterization studies
  • Fish Biology and Ecology Studies
  • Synthesis and Biological Evaluation
  • Enzyme function and inhibition
  • Synthesis and biological activity
  • Aquaculture Nutrition and Growth
  • Electrochemical sensors and biosensors
  • Algal biology and biofuel production
  • Marine Biology and Environmental Chemistry
  • Nanocomposite Films for Food Packaging
  • Neurobiology and Insect Physiology Research
  • Plant and animal studies
  • Environmental Toxicology and Ecotoxicology
  • Microbial Fuel Cells and Bioremediation
  • Invertebrate Immune Response Mechanisms

Saveetha University
2022-2025

SRM Institute of Science and Technology
2022-2025

Central Drug Research Institute
2014-2024

Tamil Nadu Agricultural University
2024

University of Pittsburgh
2023

Periyar University
2016-2022

Alagappa University
2020-2022

Vellore Institute of Technology University
2022

University of Lucknow
2014-2017

Government of Tamil Nadu
2015

Humankind is witnessing a gradual increase in cancer incidence, emphasizing the importance of early diagnosis and treatment, follow-up clinical protocols. Oral or mouth cancer, categorized under head neck cancers, requires effective screening for timely detection. This study proposes framework, OralNet, oral detection using histopathology images. The research encompasses four stages: (i) Image collection preprocessing, gathering preparing images analysis; (ii) feature extraction deep...

10.3390/biom13071090 article EN cc-by Biomolecules 2023-07-07

Synthesis of a novel series 23 triazole–butenolide conjugates utilizing click chemistry and their antileishmanial, antimalarial, antifilarial activity along with SAR, ADME predictions pharmacokinetic study are discussed.

10.1039/d2md00464j article EN RSC Medicinal Chemistry 2023-01-01

Novel β-carboline–quinazolinone hybrids are able to inhibit <italic>Leishmania donovani</italic> TR (LdTR). Molecular docking studies investigate possible binding sites were performed.

10.1039/c4md00298a article EN MedChemComm 2014-11-04

The Lantana camara Linn root extract derived gold nanoparticles (Au NPs) were characterized by Ultraviolet-Visible spectroscopy, X-ray diffraction, fourier transform-infrared, high resolution transmission electron microscopy, selected area diffraction pattern and energy dispersive analyses. In DPPH assay, the inhibitory concentration (IC50) of Au NPs gallic acid was 24.17 5.39 μg/ml, whereas, for cytotoxicity IC50 17.72 32.98 μg/ml on MBA-MB-231 Vero cells, respectively. Thus, possess...

10.1080/21691401.2016.1276923 article EN Artificial Cells Nanomedicine and Biotechnology 2017-01-09

Early childhood caries (ECC), a severe form of due to cross-kingdom interaction Candida albicans and Streptococcus mutans , is serious dental disease that affects majority the children with poor background. The present study investigated anti-infective potential thymol against C. S. dual species for management ECC. Thymol, plant derivative monoterpene group, has been well known its numerous biological activities. Thymol at 300 μg/ml concentration completely arrested growth proliferation...

10.3389/fphar.2021.760768 article EN cc-by Frontiers in Pharmacology 2021-11-19

A series of 2,3,4,9-tetrahydro-β-carboline tetrazole derivatives (14a-u) have been synthesized utilizing the Ugi multicomponent reaction and were identified as potential antileishmanial chemotypes. Most screened exhibited significant in vitro activity against promastigote (IC50 from 0.59 ± 0.35 to 31 1.27 μM) intracellular amastigote forms 1.57 0.12 17.6 0.2 L. donovani, their is comparable with standard drugs miltefosine sodium stibogluconate. The most active compound 14t was further...

10.1039/c7md00125h article EN MedChemComm 2017-01-01
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