A5014555166- Esophageal Cancer Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Gastrointestinal disorders and treatments
- Genetic factors in colorectal cancer
- Metastasis and carcinoma case studies
- Colorectal Cancer Surgical Treatments
- Radiomics and Machine Learning in Medical Imaging
- Dysphagia Assessment and Management
- Colorectal and Anal Carcinomas
- Tracheal and airway disorders
- Nutritional Studies and Diet
- Digestive system and related health
- Multiple and Secondary Primary Cancers
- Global Cancer Incidence and Screening
- Nutrition and Health Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Berberine and alkaloids research
- Lung Cancer Diagnosis and Treatment
- Stoma care and complications
- Pancreatic and Hepatic Oncology Research
The Maria Sklodowska-Curie National Research Institute of Oncology
2017-2025
National Institute of Oncology
2021-2025
Postgraduate School of Molecular Medicine
2019-2025
University of Oslo
2023-2025
Gdańsk Medical University
2023-2025
Oslo University Hospital
2024-2025
Institute for Postgraduate Medical Education
2025
MRC Cancer Unit
2020-2024
University of Cambridge
2020-2024
Cancer Research UK Cambridge Center
2022-2023
Although colonoscopy is widely used as a screening test to detect colorectal cancer, its effect on the risks of cancer and related death unclear.We performed pragmatic, randomized trial involving presumptively healthy men women 55 64 years age drawn from population registries in Poland, Norway, Sweden, Netherlands between 2009 2014. The participants were randomly assigned 1:2 ratio either receive an invitation undergo single (the invited group) or no usual-care group). primary end points...
Main Recommendations 1 ESGE suggests that high definition endoscopy, and dye or virtual chromoendoscopy, as well add-on devices, can be used in average risk patients to increase the endoscopist’s adenoma detection rate. However, their routine use must balanced against costs practical considerations. Weak recommendation, quality evidence. 2 recommends of systems individuals with Lynch syndrome. Strong 3 use, targeted biopsies, dye-based pancolonic chromoendoscopy for neoplasia surveillance...
To estimate the benefits, burden, and harms of implementing computer aided detection (CADe) polyps in colonoscopy population based screening programmes for colorectal cancer. Microsimulation modelling study. Cost effectiveness working package OperA (optimising cancer prevention through personalised treatment with artificial intelligence) project. A parallel guideline committee panel (BMJ Rapid recommendation) was consulted defining interventions selection outcome measures. Four cohorts 100...
Current guidelines recommend a 10-year interval between screening colonoscopies, but evidence is limited.To assess the long-term risk for colorectal cancer (CRC) and death from CRC after high- low-quality single negative colonoscopy.Observational study.Polish Colonoscopy Screening Program.Average-risk individuals aged 50 to 66 years who had colonoscopy (no neoplastic findings).Standardized incidence ratios (SIRs) standardized mortality (SMRs) of colonoscopy. High-quality included complete...
Intestinal metaplasia in the esophagus (Barrett's IM, or BE-IM) and stomach (GIM) are considered precursors for esophageal gastric adenocarcinoma, respectively. We hypothesize that BE-IM GIM follow parallel developmental trajectories response to differing inflammatory insults. Here, we construct a single-cell RNA-sequencing atlas, supported by protein expression studies, of entire gastrointestinal tract spanning physiologically normal pathologic states including (E-GM), BE-IM, atrophic...
Importance Patients of physicians with higher adenoma detection rates (ADRs) during colonoscopy have lower colorectal cancer (CRC) risk after screening (ie, postcolonoscopy CRC). Among an ADR above the recommended threshold, it is unknown whether improving associated a incidence CRC in their patients. Objective To determine association improved range values at baseline among Design, Setting, and Participants A total 789 Polish Colonoscopy Screening Program were studied between 2000 2017,...
Endoscopic resection techniques enable en-bloc of T1 colon cancers. A complete removal cancer can be considered curative when histologic examination the specimens shows none high-risk factors for lymph nodes metastases. Criteria predicting metastases include deep submucosal invasion, poor differentiation, lymphovascular and high-grade tumor budding. In these cases, (R0), local endoscopic is sufficient as negligible risk does not outweigh morbidity mortality associated with surgical...
This study aimed to determine long-term outcomes of gastric endoscopic submucosal dissection (ESD) in Western settings based on the latest Japanese indication criteria, and examine predictors complications.Data were collected from consecutive patients undergoing ESD at four participating centers 2009 2021. Retrospective analysis using logistic regression survival was performed.415 included (mean age 71.7 years; 56.4 % male). Absolute criteria (2018 guideline) met 75.3 patients. Median...
Background and aim Randomised trials show improved polyp detection with computer-aided (CADe), mostly of small lesions. However, operator selection bias may affect CADe’s true benefit. Clinical outcomes increased have not yet been fully elucidated. Methods In this multicentre trial, CADe combining convolutional recurrent neural networks was used for detection. Blinded endoscopists were monitored in real time by a second observer access. detections prompted reinspection. Adenoma rates (ADR)...
Artificial intelligence (AI) holds significant potential for enhancing quality of gastrointestinal (GI) endoscopy, but the adoption AI in clinical practice is hampered by lack rigorous standardisation and development methodology ensuring generalisability. The aim Quality Assessment pre-clinical studies Diagnostic Endoscopy (QUAIDE) Explanation Checklist was to develop recommendations standardised design reporting preclinical GI endoscopy.The were developed based on a formal consensus...
Endoscopic ablation is the mainstay treatment for dysplastic Barrett's esophagus (BE), of which radiofrequency (RFA) and argon plasma coagulation (APC) are most widely available options.
The full thickness resection is an innovative technique that enables non-exposed endoscopic full-thickness (EFTR) of superficial and subepithelial gastrointestinal lesions. This retrospective, multicenter study evaluated the effectiveness safety EFTR in gastroduodenal colorectal resections. Data from 105 consecutive procedures at 6 Polish centers were analyzed. Patients divided into three groups: 'difficult adenoma', adenocarcinoma, or lesion (SEL). Outcomes assessed R0 adverse event rates,...