A5013738575- Gastrointestinal motility and disorders
- Gastric Cancer Management and Outcomes
- Gastroesophageal reflux and treatments
- Colorectal Cancer Screening and Detection
- Esophageal Cancer Research and Treatment
- Diet and metabolism studies
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Anesthesia and Sedative Agents
- Gastrointestinal Bleeding Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Inflammatory Bowel Disease
- Intensive Care Unit Cognitive Disorders
- Radiomics and Machine Learning in Medical Imaging
- Enhanced Recovery After Surgery
- COVID-19 and healthcare impacts
- Intestinal Malrotation and Obstruction Disorders
- Colorectal Cancer Surgical Treatments
- Congenital gastrointestinal and neural anomalies
- Neural Networks and Applications
KU Leuven
2014-2025
Universitair Ziekenhuis Leuven
2015-2025
State of The Art
2012
Optica
2012
Catalina Scientific (United States)
2012
Catholic University of America
2004
Israelitisches Krankenhaus
1998
OBJECTIVES Studies using ambulatory pH and esophageal bile reflux monitoring (Bilitec®) have shown that both acid duodeno-gastro-esophageal (DGER) frequently occur in patients with gastroesophageal disease (GERD). A subset of GERD has persistent symptoms spite standard doses proton pump inhibitors (PPIs). The aim the present study was to investigate role DGER poorly responsive PPIs. METHODS Sixty-five (32 men, 44 ± 2 yr) without Barrett's esophagus heartburn or regurgitation during PPI were...
<b>Aims:</b> In humans, impaired gastric accommodation is associated with early satiety and weight loss. animals, involves activation of nitrergic neurones. Our aim was to study involvement nitric oxide in meal induced humans. <b>Methods:</b> The effect N<sup>G</sup>-monomethyl-l-arginine (l-NMMA) 4 mg/kg/h 8 on compliance, sensitivity distension, studied a barostat double blind, randomised, placebo controlled studies. l-NMMA using drinking test. <b>Results:</b>l-NMMA had no significant...
Background Patients with long-standing UC have an increased risk for the development of colonic neoplastic lesions. Chromoendoscopy (CE) has been proven to enhance neoplasia detection while role virtual chromoendoscopy (VC) is still be defined. Objective To compare performance CE VC lesions in patients UC. Design A multicentre prospective randomised controlled trial. 131 were between methylene blue 0.1% (n=66) or narrow band imaging (NBI) (n=65). Biopsies taken from visible and surrounding...
Duodenal hypersensitivity to acid and decreased duodenal clearance of exogenous have been reported in functional dyspepsia (FD). However, the relevance these abnormalities spontaneous exposure dyspeptic symptoms FD is unknown.To determine its relationship with symptoms, sensitivity acid, effects a 5-HT(3) receptor antagonist on responses FD.Eleven patients prominent nausea 11 healthy controls underwent 24-h ambulatory pH monitoring assessment symptoms. On next day, bolus infusions 5 ml...
Objectives: Only a few studies have applied high-resolution manometry (HRM) to the study of colonic motility in adults and none them concurrently evaluated anal motor activity. The aim was evaluate activity by means HRM healthy subjects. As present revealed presence new pattern (pan-colonic pressurizations) subjects, three additional were conducted: first second exclude that this event results from an artifact due abdominal wall contraction confirm its modulation cholinergic stimulation,...
OBJECTIVES: We sought to assess the safety, short- and long-term efficacy, durability of transcatheter embolization for lower gastrointestinal hemorrhage (LGH) unresponsive endoscopic therapy analyze overall survival embolized patients. METHODS: Between January 1997 2008, 122 patients were referred angiographic evaluation control major LGH. Overall, 43 (35.3%) presented with signs contrast extravasation. In 39 (26 men, 13 women; mean age 67.7 years), a was performed stop bleeding. RESULTS:...
Background and Study Aims: Early diagnosis of small-bowel tumors is crucial for therapy. Video capsule endoscopy has improved the diseases, but data concerning role this technique in detecting malignancy are scarce. The aim paper was to review all findings at Belgian hospitals, order evaluate diagnostic yield field malignancy. Patients Methods: For retrospective study, seven academic hospitals where device being used were asked obtained by means video endoscopy, collect information about...
OBJECTIVES It is well established that various ENT disorders and symptoms may be a manifestation of gastroesophageal reflux disease (GERD). Erosive esophagitis considered rare finding in patients therefore upper gastrointestinal (GI) endoscopy not recommended the diagnostic work-up. However, large prospective studies underscoring this policy are lacking. The aim present study was to investigate prevalence severity with suspected GERD-related chronic symptoms. METHODS Endoscopy performed 405...
Ingrid Demedts, Tatsuhiro Masaoka, Sebastien Kindt, Gert De Hertogh, Karel Geboes, Ricard Farré, Pieter Vanden Berghe and Jan Tack. J Neurogastroenterol Motil 2013;19:161-70. https://doi.org/10.5056/jnm.2013.19.2.161
Abstract Background To improve detection of mucosal lesions during colonoscopy a number imaging modalities have been suggested, including high definition and virtual chromoendoscopy. Given the theoretical advantage these new techniques, we aimed to investigate their use for polyps in patients referred large tertiary hospital. Methods Demographic, endoscopic, histological data from 1855 consecutive undergoing were collected prospectively. Patients randomly assigned three endoscopy systems...
Endoscopic mucosal resection (EMR) is the first-line treatment for large sessile and flat colorectal polyps in Western centres, however recurrence after EMR continues to be a challenge. The aim of this study assess efficacy, safety rate tertiary centre identify risk factors at first surveillance endoscopy (SE1).We performed retrospective 165 lesions ≥15 mm, treated by between 2017-2019. We used multivariate logistic regression independent SE1.EMR was 142 patients with technical success 158...
### Summary box #### What is already known about this subject? #### are the new findings? #### How might it impact on clinical practice in foreseeable future? In prospective multicentre …
Abstract Background Polyethylene glycol (PEG), bisacodyl, and prucalopride have been reported to be more effective than placebo in treating patients with constipation but about 50% of the still do not respond these medications. Only bisacodyl are expected directly stimulate colonic motility humans vivo. As no previous study has done this, aim was investigate effect PEG, as compared on assessed by means high‐resolution manometry (HRM) healthy subjects. Methods Ten subjects enrolled an acute,...
Although human postinflammatory dysmotility is known, so far animal studies have primarily investigated changes during inflammation. Here, we focused on in rat jejunal myenteric plexus and motility. Evolution of ethanol/2,4,6-tri-nitrobenzene sulphonic acid (TNBS)-induced inflammation was assessed histologically by measuring myeloperoxidase activity (MPO). Electromyography immunohistochemistry were performed 1 week after ethanol/TNBS also N(G)-nitro-L-arginine methyl ester (L-NAME)...