A5006968882- Congenital Heart Disease Studies
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Healthcare Policy and Management
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Cardiac Arrhythmias and Treatments
- Pulmonary Hypertension Research and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Family and Disability Support Research
- Mechanical Circulatory Support Devices
- Family and Patient Care in Intensive Care Units
- Tracheal and airway disorders
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Adolescent and Pediatric Healthcare
- Ultrasound and Hyperthermia Applications
- Respiratory Support and Mechanisms
- Cardiac Health and Mental Health
- Retirement, Disability, and Employment
- Blood Pressure and Hypertension Studies
- Cardiovascular Conditions and Treatments
Oregon Health & Science University
2016-2024
Cardiovascular Institute of the South
2023
University of Colorado Anschutz Medical Campus
2022
St Peter's Hospital
2021
Oregon Medical Research Center
2020
Cincinnati Children's Hospital Medical Center
2017
University of Cincinnati Medical Center
2017
Doernbecher Children's Hospital
2017
Toronto General Hospital
2017
University of Cincinnati
2017
Low serum magnesium has been linked to increased risk of atrial fibrillation (AF) after cardiac surgery. It is unknown whether hypomagnesemia predisposes AF in the community.We studied 3530 participants (mean age, 44 years; 52% women) from Framingham Offspring Study who attended a routine examination and were free cardiovascular disease. We used Cox proportional hazard regression analysis examine association between at baseline incident AF. Analyses adjusted for conventional factors, use...
The natriuretic peptides play an important role in salt homeostasis and blood pressure regulation. It has been suggested that obesity promotes a relative peptide deficiency, but this variable finding prior studies the cause is unknown.The aim of study was to examine association between levels evaluate hyperinsulinemia testosterone as mediators interaction.We studied 7770 individuals from Framingham Heart Study (n = 3833, 54% women) Malmö Diet Cancer 3918, 60% women). We examined relation...
Numerous common genetic variants have been linked to blood pressure, but no underlying mechanism has elucidated. Population studies revealed that the variant rs5068 (A/G) in 3′ untranslated region of NPPA, gene encoding atrial natriuretic peptide (ANP), is associated with pressure. We selected individuals on basis genotype (AG vs. AA) and fed them a low- or high-salt diet for 1 week, after which they were challenged an intravenous saline infusion. On both diets, before administration, ANP...
Administrative data sets utilize billing codes for research and quality assessment. Previous suggest that such can accurately identify adults with congenital heart disease (CHD) in the cardiology clinic, but their use has yet to be validated a larger population.All administrative from an entire health system were queried single year. Adults CHD diagnosis code (International Classification of Diseases, Ninth Revision, (ICD-9) 745-747) defined cohort. A previously hierarchical algorithm was...
Background The utility of longitudinal, circumferential, and radial strain rate in determining prognosis chronic heart failure is not well established. Methods Results In 416 patients with systolic failure, we performed speckle‐tracking analyses left ventricular on archived echocardiography images (30 frames per second). Cox regression models were used to determine the associations between risk all‐cause mortality, cardiac transplantation, ventricular‐assist device placement. area under...
Chronic kidney disease is associated with an increased risk of heart failure (HF). We aimed to evaluate the role large artery stiffness, brachial, and central blood pressure as predictors incident hospitalized HF in Renal Insufficiency Cohort (CRIC), a multiethnic, multicenter prospective observational study patients chronic disease.We studied 2602 participants who were free at baseline. Carotid-femoral pulse wave velocity (CF-PWV; gold standard index stiffness), pressures (estimated via...
Background This study assessed trends in heart failure ( HF) hospitalizations and health resource use patients with adult congenital disease ACHD ). Methods Results The Nationwide Inpatient Sample was used to compare non- HF hospitalization trends. Health using total hospital charges, length of stay, procedural burden. A 87 175±2676 -related occurred between 1998 2011. During this time, increased 91% (4620±438-8809±740, P<0.0001) versus a 21% increase P=0.003). associated longer stay HF,...
left ventricular (LV) rotation results from contraction of obliquely oriented myocardial fibers. The net difference between systolic apical counterclockwise and basal clockwise is torsion (LVT). Although LVT altered in various cardiac diseases, determinants are incompletely understood.LV end-diastolic volume, LV rotation, peak LVT, early diastolic untwisting rate were measured by speckle-tracking echocardiography healthy subjects (n=8) before after infusion a weight-based normal saline bolus...
Summary Background and objective Fibroblast growth factor 23 (FGF-23), a regulator of phosphorus metabolism, is risk marker in CKD. FGF-23 has been associated with coronary arterial calcification (CAC), but it not known whether predicts CAC progression The aim this study was to evaluate the association advanced Design, setting, participants, & measurements levels were measured by electrocardiography-triggered multislice computed tomography 99 individuals initiating dialysis. Patients...
Abstract Background Adults with congenital heart disease face psychological challenges although an understanding of depression vs. anxiety symptoms is unclear. We analyzed the prevalence elevated and explored associations demographic medical factors as well quality life. Methods enrolled from outpatient clinic completed Hospital Anxiety Depression Scale two measures life: Linear Analogue Satisfaction Life Scale. Medical data were obtained by chart review. Results Of 130 patients (median age...
In epidemiologic studies, obesity has been associated with reduced natriuretic peptide (NP) concentrations. Reduced NP production could impair the ability of obese individuals to respond salt loads, increasing risk hypertension and other disorders. We hypothesized that weight loss enhances before after loading.We enrolled 15 (mean BMI 45±5.4 kg/m(2)) undergoing gastric bypass surgery. Before 6 months surgery, subjects were admitted clinical research center administered a large-volume...
Variability in the duration of attempted in‐hospital cardiopulmonary resuscitation (CPR) is high, but factors influencing termination CPR efforts are unknown.We examined association between patient and hospital characteristics 45 500 victims cardiac arrest who did not experience return spontaneous circulation (ROSC) were enrolled Get With Guidelines registry 2001 2010. In a secondary analysis, we performed analyses 46 168 experienced ROSC. We used ordered logistic regression to identify...
Prior studies have demonstrated that elevated aldosterone concentrations are an independent risk factor for death in patients with cardiovascular disease. Limited studies, however, evaluated systematically the association between serum and adverse events setting of chronic kidney We investigated end-stage renal disease 3866 participants from Chronic Renal Insufficiency Cohort. also incident congestive heart failure atherosclerotic without baseline Cox proportional hazards models were used to...