A5058163832- Bryophyte Studies and Records
- Botany and Plant Ecology Studies
- Regulation of Appetite and Obesity
- DNA and Nucleic Acid Chemistry
- RNA and protein synthesis mechanisms
- Plant Parasitism and Resistance
- Biochemical Analysis and Sensing Techniques
- Lichen and fungal ecology
- Crustacean biology and ecology
- Plant Taxonomy and Phylogenetics
- Legume Nitrogen Fixing Symbiosis
- Genomics and Phylogenetic Studies
- Photosynthetic Processes and Mechanisms
- Plant and animal studies
- Genetic diversity and population structure
- Plant Diversity and Evolution
- Plant Pathogens and Fungal Diseases
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Protist diversity and phylogeny
- Marine animal studies overview
- HIV/AIDS drug development and treatment
- Click Chemistry and Applications
- Ecology and Vegetation Dynamics Studies
- Chemical Synthesis and Analysis
Natural England
2023
Amgen (United States)
2017-2021
University of Akron
2010-2020
Western Washington University
2014
Southern Illinois University Carbondale
1997-2009
Center for Biologics Evaluation and Research
2008
Center for Drug Evaluation and Research
2008
Johns Hopkins University
2000-2002
Indiana University Bloomington
2000
Southern Illinois University System
2000
Phylogenetic relationships among the four major lineages of land plants (liverworts, mosses, hornworts, and vascular plants) remain vigorously contested; their resolution is essential to our understanding origin early evolution plants. We analyzed three different complementary data sets: a multigene supermatrix, genomic structural character matrix, chloroplast genome sequence using maximum likelihood, parsimony, compatibility methods. Analyses all sets strongly supported liverworts as sister...
An in silico screen of 41 the 81 coding regions Nicotiana plastid genome generated a shortlist 12 candidates as DNA barcoding loci for land plants. These were evaluated amplification and sequence variation against reference set 98 plant taxa. The deployment multiple primers modified multiplexed tandem polymerase chain reaction yielded 85–94% across taxa, mean differences between sister taxa 6.1 from 156 bases accD to 22 493 matK. We conclude that should be combined effective diagnosis,...
A widely held view of land plant relationships places liverworts as the first branch tree, whereas some molecular analyses and a cladistic study morphological characters indicate that hornworts are earliest plants. To help resolve this conflict, we used parsimony likelihood methods to analyze 6, 095-character data set composed four genes (chloroplast rbcL small-subunit rDNA from all three genomes) major lineages. In analyses, significant support was obtained for monophyly vascular plants,...
Revolutionary new concepts of bryophyte relationships have emerged from molecular phylogenetic analyses conducted since the onset 21st century. For example, sequence data contradict historical notion that isophylly in leafy liverworts is plesiomorphic and simple thalloid are monophyletic. Also contrary to traditional views Leiosporoceros genetically distinct other hornworts Oedipodium sister peristomate mosses. Substantial increases ultrastructural anatomical likewise provided insights on...
All organisms face tradeoffs with regard to how limited energy resources should be invested. When is it most favorable grow, reproduce, much lipid allocated storage in preparation for a period of (e.g., winter), instead being used growth or maturation? These are few the high consequence fitness "decisions" that represent balance between acquisition and allocation. Indeed, animals make decisions about when eat, they must integrate signals among systems responsible acquisition, storage,...
Phylogenetic relationships among embryophytes (tracheophytes, mosses, liverworts, and hornworts) were examined using 21 newly generated mitochondrial small-subunit (19S) rDNA sequences. The "core" 19S contained more phylogenetically informative sites lower homoplasy than either nuclear 18S or plastid 16S rDNA. Results of phylogenetic analyses parsimony (MP) likelihood (ML) generally congruent. Using MP, two trees obtained that resolved liverworts hornworts as the basal land plant clade....
Leptin is a pleiotropic protein best known for regulation of appetite and fat storage in mammals. While many leptin orthologs have been identified among vertebrates, an authentic birds has remained elusive controversial. Here we identify sequence from the Peregrine falcon, Falco peregrinus (pfleptin), sequences two other (mallard zebra finch), 'missing' vertebrates (elephant shark, alligator, Indian python, Chinese soft-shelled turtle, coelacanth). The pattern genes surrounding (snd1, rbm28)...
Over a decade passed between Friedman's discovery of the mammalian leptin gene (1) and its cloning in fish (2) amphibians (3). Since 2005, concept synteny conservation (vs. sequence homology) was instrumental identifying genes dozens species, we now have from all major classes vertebrates. This database LEP (leptin), LEPR (leptin receptor), LEPROT (endospanin) has allowed protein structure modeling, stoichiometry predictions, even functional predictions function for most vertebrate classes....
Molecular phylogenetic analyses of hornworts were performed on a nucleotide data set consisting mitochondrial nad5, chloroplast rbcL and nuclear 18S gene regions. Thirty-seven representing most the named generic segregates morphological diversity in group sampled for three analysis while an additional 25 samples included alone. Results these confirm relationships observed prior molecular studies but also reveal number previously unrecognized yet highly supported clades. On basis this...
The assembled Physcomitrella patens genome has been released. This provides a unique opportunity to identify and characterize new genes, compare moss genes with other plant from previously released genomes. Aldehyde dehydrogenases (ALDHs) comprise protein superfamily of NAD(P) -dependent enzymes [EC 1.2.1] found in bacteria, animals green plants capable oxidizing variety aromatic aliphatic aldehydes. ALDHs are key abiotic stress-tolerance organisms. In bryophytes, postulated play role...
The desiccation-tolerant moss Tortula ruralis [Hedw.] Gaerten., Meyer & Scherb. has both a constitutive protection system and an active rehydration induced recovery mechanism apparently unique to bryophytes. Immediately following rehydration, desiccated T. gametophytes produce set of polypeptides whose synthesis is the rehydrated state. We report construction cDNA expression library from polysomal mRNA single-pass sequencing randomly selected clones. 152 expressed sequence tags (ESTs) were...
ABSTRACT. The value of molecular databases for unicellular eukaryotic identification and phylogenetic reconstruction is predicated on the availability sequences accuracy taxonomic identifications that accompany those sequences. Biased representation due in part to differing ability isolate culture various groups protists. Techniques allow parallel single‐cell morphological have been reported a few We sought explore how techniques can be adapted work across greater diversity taxa. Twelve...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExchange of amide protons. Effect intramolecular hydrogen bondingCharles L. Perrin, Tammy J. Dwyer, Julius Rebek Jr., and Robert DuffCite this: Am. Chem. Soc. 1990, 112, 8, 3122–3125Publication Date (Print):April 1, 1990Publication History Published online1 May 2002Published inissue 1 April 1990https://pubs.acs.org/doi/10.1021/ja00164a037https://doi.org/10.1021/ja00164a037research-articleACS PublicationsRequest reuse permissionsArticle...
Chromosomes that determine sex are predicted to evolve differently than autosomes: a lack of recombination on one the two chromosomes is allow an accumulation deleterious alleles eventually leads reduced functionality and potential physical degradation nonrecombining chromosome. Because these changes should occur at elevated evolutionary rate, it difficult find appropriate species in which test predictions. The unique genetic sex-determining mechanism crustacean Eulimnadia texana prevents...
Tortula ruralis (Syntrichia ruralis) is an important model system for the study of plant vegetative desiccation tolerance. One most intriguing aspects desiccation-tolerant plants maintenance key cellular components in stable and viable forms desiccated state, particularly those related to translational apparatus (i.e. ribosomes ribosomal RNAs). This investigated third integral component apparatus, proteins. Three T. cDNAs encoding predicted polypeptides with significant similarity proteins...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEvidence for C-1' hydrogen abstraction from modified oligonucleotides by iron-bleomycinRobert J. Duff, Erik de Vroom, Annemiek Geluk, Sidney M. Hecht, Gijs A. van der Marel, and Jacques H. BoomCite this: Am. Chem. Soc. 1993, 115, 8, 3350–3351Publication Date (Print):April 1, 1993Publication History Published online1 May 2002Published inissue 1 April...