Yuan Gao

ORCID: 0000-0003-3816-0133
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About
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Research Areas
  • Peptidase Inhibition and Analysis
  • Nanoparticle-Based Drug Delivery
  • Molecular Sensors and Ion Detection
  • Parasite Biology and Host Interactions
  • Advanced Radiotherapy Techniques
  • Helminth infection and control
  • Medical Imaging Techniques and Applications
  • Gut microbiota and health
  • Inflammatory Myopathies and Dermatomyositis
  • Liver physiology and pathology
  • Augmented Reality Applications
  • Sirtuins and Resveratrol in Medicine
  • Radiation Therapy and Dosimetry
  • Coconut Research and Applications
  • Liver Disease Diagnosis and Treatment
  • Hydrogen Storage and Materials
  • Hip and Femur Fractures
  • Natural Antidiabetic Agents Studies
  • Calpain Protease Function and Regulation
  • Cell death mechanisms and regulation
  • Nuts composition and effects
  • Facial Rejuvenation and Surgery Techniques
  • Tea Polyphenols and Effects
  • Cytokine Signaling Pathways and Interactions
  • Surgical Simulation and Training

Guangdong Ocean University
2024

Jiangsu University
2024

Xuzhou Cancer Hospital
2024

Western Eye Hospital
2024

Western General Hospital
2024

Imperial College Healthcare NHS Trust
2024

Affiliated Hospital of Taishan Medical University
2024

Shandong First Medical University
2024

Emory University
2024

Georgia Institute of Technology
2023

Flavonoids are widely distributed in natural products and foods as a class of polyphenols. They processed diverse bioactivities, including anti-inflammation activity, antiaging antioxidant activity. The rich flavonoids usually consumed after thermal processing. However, commonly vulnerable under processing, it could cause various influences on their stability bioactivities. Therefore, this review, the effects processing bioactivities dietary from different food sources were first summarized....

10.1016/j.cofs.2022.100915 article EN cc-by-nc-nd Current Opinion in Food Science 2022-08-29

Aristolochic Acid (AA), a natural component of Aristolochia plants that is found in variety herbal remedies and health supplements, classified as Group 1 carcinogen by the International Agency for Research on Cancer. Given microRNAs (miRNAs) are involved cancer initiation progression their role remains unknown AA-induced carcinogenesis, we examined genome-wide dysregulation miRNAs well regulation target gene expression rat kidney. We treated rats with 10 mg/kg AA vehicle control 12 weeks...

10.1186/s12864-015-1516-2 article EN cc-by BMC Genomics 2015-05-07

Acute myelogenous leukemia (AML) remains a serious fatal disease for the patients and effective treatment strategies are urgently needed. Based on characteristics of AML, we developed CD44 bone targeting liposomes delivery system decorated with redox-cleavable polymer. First, ALN-HA was obtained by amination between alendronate (ALN) hyaluronic acid (HA), cholesterol (Chol) coupled disulfide linker (-SS-) biological reducibility to obtain goal polymer, ALN-HA-SS-Chol, loaded Cytarabine...

10.1093/rb/rbac058 article EN cc-by Regenerative Biomaterials 2022-01-01

The downregulation of microRNA (miR)-381 has been detected in various diseases. present study aimed to investigate the effects, and underlying mechanisms miR-381 on inflammation macrophage infiltration polymyositis (PM). A mouse model experimental autoimmune myositis (EAM) was generated this study. Hematoxylin eosin staining conducted detect muscle tissues. In addition, ELISA immunohistochemistry were performed determine expression levels associated factors, reverse...

10.3892/ijo.2018.4463 article EN International Journal of Oncology 2018-06-29

Abstract Despite the benefit with cancer immunotherapies in clinical implication, immunotherapeutic resistance occurred many patients and mechanism remains unknown. Increasing evidence has revealed that cell‐intrinsic programmed cell death ligand 1 (PD‐L1) may play a non‐negotiable part resistance. Our present study aimed to elucidate immune‐independent acquired PD‐L1 antibody. We found elevated expression induced by antibodies vascular endothelial cells (VECs) substantially antibodies....

10.1002/cam4.6195 article EN cc-by Cancer Medicine 2023-06-23

To investigate the metacercarial infections of fishborne zoonotic trematodes (FZT), a total 6815 freshwater fish (in representing 13 species 5 families) were collected from Songhua river (n = 2636), Nenjiang 1935), Mudanjiang 301), and other lakes or ponds 1943) in 36 representative regions Heilongjiang Province, China, August 2012 to December 2015. Metacercariae four FZT species, that is, Clonorchis sinensis, Metorchis orientalis, Isthmiophora hortensis, Metagonimus yokogawai, metacercariae...

10.1089/fpd.2016.2249 article EN Foodborne Pathogens and Disease 2017-07-24

Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging modality implementation of adaptive (ART) protocols. Nonetheless, significant artifacts and incorrect Hounsfield unit (HU) values hinder their application quantitative tasks such as target organ segmentations dose calculation. Therefore, acquiring CT-quality images from CBCT...

10.1002/mp.17572 article EN Medical Physics 2024-12-12

To compare intraocular pressure (IOP) during the water drinking test (WDT) and modified diurnal tension curve (mDTC) in open-angle glaucoma (OAG) patients, using multimodal, observer-masked tonometry.

10.1038/s41433-024-02954-0 article EN cc-by Eye 2024-03-07

We sought to explore the effectiveness of cannulated screw fixation for femoral neck fractures in middle-aged and elderly patients assisted by a three-dimensional printing navigation template.

10.26355/eurrev_202404_36049 article EN PubMed 2024-04-01

Mapping computed tomography (CT) number to material property dominates the proton range uncertainty. This work aims develop a physics-constrained deep learning-based multimodal imaging (PDMI) framework integrate physics, learning, magnetic resonance (MRI), and advanced dual-energy CT (DECT) derive accurate patient mass density maps. Seven tissue substitute MRI phantoms were used for PDMI-based calibration. The training inputs are from twin-beam images acquired at 120 kVp with gold tin...

10.48550/arxiv.2207.13150 preprint EN other-oa arXiv (Cornell University) 2022-01-01
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