- Parasite Biology and Host Interactions
- Helminth infection and control
- Parasites and Host Interactions
- Genomics and Phylogenetic Studies
- Identification and Quantification in Food
- Nematode management and characterization studies
- Vector-borne infectious diseases
- Study of Mite Species
- Parasitic Infections and Diagnostics
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Insect symbiosis and bacterial influences
- Cancer-related molecular mechanisms research
- Ethnobotanical and Medicinal Plants Studies
- Mosquito-borne diseases and control
- Parasitic Diseases Research and Treatment
- Marine Ecology and Invasive Species
- Coccidia and coccidiosis research
- Drug-Induced Hepatotoxicity and Protection
- Ichthyology and Marine Biology
- Immune responses and vaccinations
- Mollusks and Parasites Studies
- Medicinal Plants and Neuroprotection
- Insect Pest Control Strategies
Jilin University
2021-2024
Heilongjiang Bayi Agricultural University
2018-2022
Abstract Background Fish-borne zoonotic clonorchiasis, caused by Clonorchis sinensis , is an emerging public health problem in several countries with more than 15 million people infected globally. However, a lack of accurate point-of-care (POC) diagnostic tests resource-limited areas still critical barrier to effective treatment and control clonorchiasis. The development the recombinase polymerase amplification(RPA) assay, POC test based on amplification pathogen DNA, has provided new,...
Anisakis can cause Anisakiasis in humans if raw or undercooked fish is consumed. Symptoms of infection may include vomiting, acute abdominal symptoms, allergies. In this study, we collected 187 commercially available marine from the Yellow Sea, East China and South Sea. Among them, 79 were found positive containing 520 worms. The average prevalence rate was 42% investigation. Ninety-two worms different sea areas selected analyzed for identification, revealing presence five species, which are...
Anisakidosis is a food-borne parasitic disease (FBPD) caused by the third-stage larvae of family Anisakidae. Therefore, it important to develop simple, rapid and equipment-free detection method for anisakids in fish samples or seafood since current methods are time-consuming require complex instruments. In this study, recombinase polymerase amplification (RPA)-based was established first time detect targeting internal transcribed spacer (ITS) regions. The results were visualized including...
Clonorchis sinensis is a significant zoonotic food-borne parasite that causes range of hepatobiliary diseases, which in severe cases can even lead to cholangiocarcinoma. To explore new diagnostic and treatment strategies, the dynamic RNA regulatory processes across different developmental stages C . were analyzed by using whole-transcriptome sequencing. The chromosomal-level genome was used for sequence alignment annotation. In this study, we identified total 59,103 RNAs whole genome,...
Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to development of and gallbladder diseases, even cholangiocarcinoma (CCA). However, pathogenesis, host-pathogen interaction, diagnostic markers for clonorchiasis remain unclear. Eighteen rabbits were randomly divided into control group (n = 9) C. sinensis-infected 9), their plasma samples collected at 7, 14, 28, 63 days post-infection (dpi). Biochemical indices metabolites in different infection...
Diplodiscus japonicus and mehari (Trematoda: Diplodiscidae) are two important parasites in wood frogs, which have large infection rates essential importance of ecology, economy society. In this study, the complete mitochondrial (mt) genomes D. were sequenced, then compared with other related trematodes superfamily Paramphistomoidea. The circular mt sequence 14,210 bp 14,179 length, respectively. Both comprised 36 functional subunits, consisting 12 protein-coding genes (PCGs), ribosomal RNA...
Clonorchiasis, which is caused by Clonorchis sinensis , an important foodborne disease worldwide. The excretory-secretory products (ESPs) of C. play roles in host-parasite interactions acting as causative agents. In the present study, ESPs and sera positive for were collected to identify proteins specific (i.e., that do not cross-react with Fasciola hepatica Schistosoma japonicum ) at different infection periods. Briefly, white Japanese rabbits artificially infected their 7 days...
Abstract The parasite Cyathostomum pateratum , which occurs in the large intestine of equines, is a common species subfamily Cyathostominae. Cyathostominae nematodes are complex nematode group for only limited genetic information has been reported. To re-examine phylogenetic relationships among nematodes, we sequenced complete mitochondrial (mt) genome Cy. and compared it with mt congeneric catinatum. mtDNA sequence was 13,822 bp length, 16 shorter than that sequences both contained 12...
In the past 30 years, few researches focus on efficacy of adjuvant against Trichinella spiralis infection. Identifying new, improved vaccine adjuvants for T. infection are required. β-glucan effective and safe as infectious diseases. this paper, we first observed adjuvanticity defensing helminth in vivo . We showed that IgG IgE were elevated mice immunized with combined recombinant serine protease inhibitor (r Ts -Serpin), which is one candidates. Furthermore, vitro , combination r -Serpin...
Metorchis orientalis is a neglected zoonotic parasite of the gallbladder and bile duct poultry, mammals, humans. It has been widely reported in Asian, including China, Japanese, Korea, where it potential threat to public health. Despite its significance as an animal human pathogen, there are few published transcriptomic proteomics data available. Transcriptome Illumina RNA sequencing label-free protein quantification were performed compare gene expression adult metacercariae-stage M. ,...
The complete mitochondrial genome of Haemaphysalis japonica is reported for the first time in this study. Its entire mitogenome 14,685 bp length, containing 13 protein-coding genes, two ribosomal RNA 22 transfer and non-coding regions. phylogenetic analysis by Bayesian inference method show that H. other species genus formed one clade, indicating belongs to Haemaphysalis.