- Cardiovascular and Diving-Related Complications
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Long-Term Effects of COVID-19
- Restraint-Related Deaths
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Tracheal and airway disorders
- High Altitude and Hypoxia
- Acute Ischemic Stroke Management
- Congenital Diaphragmatic Hernia Studies
- COVID-19 and healthcare impacts
- Pneumothorax, Barotrauma, Emphysema
- Abdominal Surgery and Complications
- Hip and Femur Fractures
- Nosocomial Infections in ICU
- Peripheral Artery Disease Management
- COVID-19 and Mental Health
- Intensive Care Unit Cognitive Disorders
- COVID-19 Impact on Reproduction
- Antibiotic Use and Resistance
James Paget University Hospital
2012-2024
James Paget University Hospitals NHS Foundation Trust
2009-2024
Whipps Cross University Hospital
2014-2023
St Mary's Hospital
2023
International Severe Acute Respiratory and Emerging Infection Consortium
2023
The Queen's Medical Research Institute
2022
Centre for Inflammation Research
2022
University of Edinburgh
2022
Roslin Institute
2022
University College London Hospitals NHS Foundation Trust
2020
Intravascular haemolysis is a rare but serious complication of Clostridium perfringens sepsis. The outcome usually fatal unless treatment started early. We describe case survival after and multiple organ failure in the setting ruptured liver abscess sepsis caused by C. an immunocompetent 58-year-old male.
We studied anthrax immune globulin intravenous (AIG-IV) use from a 2009-2010 outbreak of Bacillus anthracis soft tissue infection in injection drug users Scotland, UK, and we compared findings 15 AIG-IV recipients with 28 nonrecipients. Death rates did not differ significantly between nonrecipients (33% vs. 21%). However, whereas only 8 (27%) 30 patients at low risk for death (admission sequential organ failure assessment score 0-5) received AIG-IV, 7 (54%) the 13 high (sequential 6-11)...
A man in his 30s presented with a brief episode of vomiting, acute abdominal pain and subsequent development shortness breath. On initial examination investigation, the clinical impression was right-sided pneumothorax, pneumonia pleural effusion. Early antibiotic treatment management showed improvement, patient reporting resolution symptoms. This short lived, further deterioration condition worsening Ensuing examination, imaging investigations demonstrated an oesophageal leak into right...
To evaluate the Springfusor® infusion device for clinical use in an Intensive Care Unit and to compare technique of intermittent bolus constant muscle relaxants, we undertook a prospective double-blind randomized placebo-controlled study. Twenty critically ill ventilated patients requiring paralysis were investigated. Although could show no advantage infusing vecuronium, provided more level compared with hourly doses. The is robust, easy reduces nursing workload. This may translate into...
Objectives Admission of patients with necrotising otitis externa (NOE) has been rising steadily over the last five years and mortality morbidity associated disease is high. Our objective to assess value adjuvant hyperbaric oxygen therapy in externa. Design setting A retrospective, observational, case-control study was conducted by examining patients’ records a four-and-a-half-year period at two secondary care sites UK. The (Non-HBO) control group treated conventionally (HBO) additional HBO...