A5025711158- Cardiac, Anesthesia and Surgical Outcomes
- Soviet and Russian History
- Hip and Femur Fractures
- Eastern European Communism and Reforms
- Enhanced Recovery After Surgery
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Scottish History and National Identity
- Post-Communist Economic and Political Transition
- Respiratory viral infections research
- SARS-CoV-2 detection and testing
- World Wars: History, Literature, and Impact
- Viral gastroenteritis research and epidemiology
- Philippine History and Culture
- Sepsis Diagnosis and Treatment
- American Constitutional Law and Politics
- Appendicitis Diagnosis and Management
- Historical and Cultural Studies of Poland
- Airway Management and Intubation Techniques
- Biosensors and Analytical Detection
- Social Policy and Reform Studies
- COVID-19 Clinical Research Studies
- European Political History Analysis
- Abdominal Surgery and Complications
- SARS-CoV-2 and COVID-19 Research
Newcastle University
2008-2022
Royal Victoria Infirmary
2001-2021
Newcastle upon Tyne Hospitals NHS Foundation Trust
2012-2021
Public Health England
2017
North Tyneside General Hospital
2007-2009
University of Waterloo
2006
Royal Perth Hospital
2006
Wellcome Centre for Mitochondrial Research
2005
We investigated whether positioning patients undergoing general anaesthesia for cholecystectomy in a 20 degrees head-up position, as opposed to supine, improved the efficacy of 3 min standard pre-oxygenation via circle breathing system. Following pre-oxygenation, received induction and apnoea time (from administration rocuronium arterial oxygen saturation fall 95%) was recorded. Mean (95% CI) 386 (343-429) s position (n = 17) vs 283 (243-322) supine 18; p 0.002). Pre-oxygenation is...
Abstract Background Textbook outcomes are composite outcome measures that reflect the ideal overall experience for patients. There many of these in elective surgery literature but no textbook have been proposed patients following emergency laparotomy. The aim was to achieve international consensus amongst experts and best Outcomes non-trauma trauma Methods A modified Delphi exercise undertaken with three planned rounds regarding based on category, number importance (Likert scale 1–5)...
Pulmonary A2 strain respiratory syncytial virus infection of BALB/c laboratory mice persisted for up to 7 days after initial with peak titres being recovered on day 4. Virus antigen within the lungs was found be restricted essentially alveolar regions. Similarly, pulmonary histopathological changes remained confined peri-alveolar regions consistent mild pneumonia. Infection elicit a major histocompatibility complex-restricted cytotoxic T lymphocyte (CTL) response which first detectable 6 and...
Healthcare workers (HCWs) are known to be at increased risk of infection with SARS-CoV-2, although whether these risks equal across all roles is uncertain. Here we report a retrospective analysis large real-world dataset obtained from 10 March 6 July 2020 in an NHS Foundation Trust England 17,126 employees. 3,338 HCWs underwent symptomatic PCR testing (14.4% positive, 2.8% staff) and 11,103 serological for SARS-CoV-2 IgG (8.4% 5.5% staff). Seropositivity was lower than other hospital...
Thoracic epidural (TE) analgesia has been the standard of care for transthoracic esophagectomy patients since 1990s. Multimodal anesthesia using intrathecal diamorphine, local anesthetic infusion catheters (LAC) into paravertebral space and rectus sheaths intravenous opioid postoperatively represent an alternative option postoperative analgesia. While TE can provide excellent pain control, it may inhibit early recovery by causing hypotension reducing mobilization. The aim this study is to...
Saunders, D. I.; Murray, D.; Pichel, A. C.; Varley, S.; Peden, C. J. On Behalf of the Members UK Emergency Laparotomy Network Author Information
Abstract Background Emergency laparotomy carries a significant risk profile around the time of surgery. This research aimed to establish feasibility recruitment study using validated scoring tools assess complications after surgery; and patient-reported outcome measures (PROMs) quality life recovery up year following emergency (EL). Methods We used our local National Laparotomy Audit (NELA) register identify potential participants at single NHS centre in England. Complications were assessed...
Britain began limiting the entry of non‐nationals in 1905, but control aliens became much more rigorous as a result First World War. Germans were not only nationality to trouble authorities. On one hand, most Russian citizens who lived unsympathetic war effort, despite fact that they subjects friendly power. other some Britain's Austro‐Hungarian residents supported British might have been expected oppose it. In view these complexities, alien ‘friends’ had be treated enemies and ‘enemies’...
Abstract Background Thoracic epidural analgesia (TEA) has been regarded as the standard of care after oesophagectomy for pain control, but several side-effects. Multimodal (intrathecal diamorphine, paravertebral and rectus sheath catheters) (MA) may facilitate postoperative mobilization by reducing hypotensive episodes need vasopressors, uncertainty exists about whether it provides comparable analgesia. This study aimed to determine MA TEA following transthoracic oesophagectomy. Methods...
Purpose. To evaluate the Luminex NxTAG respiratory pathogen panel (NxTAG RPP) for detection of viruses in clinical samples from patients with symptoms infection. Methodology. The RPP was compared to an in-house multiplex real-time PCR (LDT) 314 Results. Thirty-one were negative both tests and 193 contained a single virus that detected tests. Polymicrobial infections 74 samples, 268 overall having concordant results assays, there total 51 discordant 44 samples. Two invalid assay excluded...
ABSTRACT This paper discusses the motives underlying two approaches to development of Russian Arctic in late nineteenth century. The first, brainchild British merchant seaman Joseph Wiggins (1832–1905), derived principally from private commercial instincts. second, work Sergei Witte (1849–1915), Russia's Minister Finance, and innovative Admiral Stepan Osipovich Makarov (1848–1904), had much less do with trade more projecting national ambitions. first required no great technological insight,...
This article contrasts the picture which President Vladimir Putin paints of Ukraine with vigour Ukrainians displayed at time Ukrainian Revolution 1917–20.
Britain and the Ukrainian Question (1912–1920) Get access DAVID SAUNDERS University of Newcastle upon Tyne Search for other works by this author on: Oxford Academic Google Scholar The English Historical Review, Volume CIII, Issue CCCCVI, January 1988, Pages 40–68, https://doi.org/10.1093/ehr/CIII.CCCCVI.40 Published: 01 1988