Jaebum Choo

ORCID: 0000-0003-3864-6459
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About
Contact & Profiles
Research Areas
  • Biosensors and Analytical Detection
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced biosensing and bioanalysis techniques
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Microfluidic and Capillary Electrophoresis Applications
  • Advanced Biosensing Techniques and Applications
  • Microfluidic and Bio-sensing Technologies
  • SARS-CoV-2 detection and testing
  • Advanced Chemical Physics Studies
  • Photochemistry and Electron Transfer Studies
  • Molecular Spectroscopy and Structure
  • Quantum Dots Synthesis And Properties
  • Analytical Chemistry and Sensors
  • Spectroscopy and Laser Applications
  • Nanocluster Synthesis and Applications
  • Electrochemical Analysis and Applications
  • Advanced Nanomaterials in Catalysis
  • Molecular spectroscopy and chirality
  • Electrowetting and Microfluidic Technologies
  • Spectroscopy and Chemometric Analyses
  • SARS-CoV-2 and COVID-19 Research
  • Nanoplatforms for cancer theranostics
  • Lipid Membrane Structure and Behavior
  • Nanoparticle-Based Drug Delivery

Chung-Ang University
2019-2025

Columbia University
2023

Michigan State University
2023

University of Michigan
2023

University of Liverpool
2023

The University of Texas at El Paso
2023

Stockholm University
2023

Curtin University
2023

Rutherford Appleton Laboratory
2023

Confederazione Nazionale dell'Artigianato e Della Piccola e Media Impresa
2023

The discovery of the enhancement Raman scattering by molecules adsorbed on nanostructured metal surfaces is a landmark in history spectroscopic and analytical techniques. Significant experimental theoretical effort has been directed toward understanding surface-enhanced (SERS) effect demonstrating its potential various types ultrasensitive sensing applications wide variety fields. In 45 years since discovery, SERS blossomed into rich area research technology, but additional efforts are still...

10.1021/acsnano.9b04224 article EN publisher-specific-oa ACS Nano 2019-09-03

Particle-larly good! Thermal annealing and etching of physical composite butyl-capped Si gels SiO2 nanoparticles at 900 °C under an Ar atmosphere is a versatile method for the formation 3D porous bulk particles (see picture). Complete from SiO2/carbon-coated (c-Si) results in retention remaining c-Si as highly but interconnected structure, which preserves starting morphology.

10.1002/anie.200804355 article EN Angewandte Chemie International Edition 2008-11-17

Baseline correction methods based on penalized least squares are successfully applied to various spectral analyses. The change the weights iteratively by estimating a baseline. If signal is below previously fitted baseline, large weight given. On other hand, no or small given when above baseline as it could be assumed part of peak. As noise distributed well however, desirable give same similar in either case. For purpose, we propose new weighting scheme generalized logistic function....

10.1039/c4an01061b article EN The Analyst 2014-09-29

Accurate analysis of specific biomarkers in clinical serum is essential for early diagnosis and treatment cancer. Here, a surface-enhanced Raman scattering (SERS)-based immunoassay, using magnetic beads SERS nano tags, was developed the determination free to total (f/t) prostate antigen (PSA) ratio improve diagnostic performance To assess applicability proposed method, SERS-based assays simultaneous detection dual PSA markers, (f-PSA) complexed (c-PSA), were performed samples gray zone...

10.1021/acsnano.7b01536 article EN ACS Nano 2017-04-25

A quick and reproducible surface-enhanced Raman scattering (SERS)-based immunoassay technique, using hollow gold nanospheres (HGNs) magnetic beads, has been developed. Here, HGNs show strong enhancement effects from individual particles because hot spots can be localized on the pinholes in particle structure. Thus, used for highly immunoanalysis of cancer markers. Magnetic beads were as supporting substrates formation immunocomplex. This SERS-based technique overcomes problem slow...

10.1021/ac802722c article EN Analytical Chemistry 2009-03-20

A novel surface-enhanced Raman scattering (SERS)-based lateral flow immunoassay (LFA) biosensor was developed to resolve problems associated with conventional LFA strips (<italic>e.g.</italic>, limits in quantitative analysis and low sensitivity).

10.1039/c5nr07243c article EN Nanoscale 2016-01-01

A new class of surface-enhanced Raman scattering (SERS)-based lateral flow assay (LFA) biosensor has been developed for the simultaneous detection dual DNA markers. The LFA strip in this sensor was composed two test lines and one control line. SERS nano tags labeled with probes were used quantitative evaluation markers high sensitivity. Target DNA, associated Kaposi's sarcoma-associated herpesvirus (KSHV) bacillary angiomatosis (BA), tested to validate capability SERS-based strip....

10.1021/acs.analchem.6b03536 article EN Analytical Chemistry 2016-11-22

We developed a new surface-enhanced Raman scattering (SERS)-based aptasensor platform capable of quantifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lysates with high sensitivity. In this study, spike protein deoxyribonucleic acid (DNA) aptamer was used as receptor, and self-grown Au nanopopcorn surface SERS detection substrate for the sensible SARS-CoV-2. A quantitative analysis SARS-CoV-2 lysate performed by monitoring change in peak intensity caused binding between...

10.1021/acssensors.1c00596 article EN ACS Sensors 2021-05-21

A wearable surface-enhanced Raman scattering (SERS) sensor has been developed as a patch type to utilize molecular sweat sensor. Here, the SERS is designed comprise sweat-absorbing layer, which an interface human skin, active and dermal protecting layer that prevents damage contaminations. silk fibroin protein film (SFF) basement absorbs aqueous solutions filtrates molecules larger than nanopores created in β-sheet matrix of SFF. On SFF plasmonic silver nanowire (AgNW) formed enhance signal...

10.1021/acsami.0c18892 article EN ACS Applied Materials & Interfaces 2021-01-06

Surface-enhanced Raman scattering (SERS) imaging has been used for the targeting and of specific cancer markers in live cells. For this purpose, Au/Ag core−shell nanoparticles, conjugated with monoclonal antibodies, were prepared. The procedures to label cells those bimetallic nanoprobes have developed highly sensitive SERS In present study, HEK293 expressing PLCγ1 as optical target. Our results demonstrate potential feasibility technology biomarkers

10.1021/ac061246a article EN Analytical Chemistry 2007-01-06

Thermische Behandlung und Ätzen eines physikalischen Gemischs aus einem Si-Gel mit Butyl-Endgruppen SiO2-Nanopartikeln bei 900 °C in Argonatmosphäre führen zu dreidimensionalen porösen Si-Partikeln (siehe Bild). Nach dem vollständigen Entfernen des SiO2 verbleibt kohlenstoffbeschichtetes Si (c-Si) als hoch poröse, aber zusammenhängende Struktur der ursprünglichen Morphologie.

10.1002/ange.200804355 article DE Angewandte Chemie 2008-11-17
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