A5103164070- Immune Cell Function and Interaction
- Transcranial Magnetic Stimulation Studies
- Stroke Rehabilitation and Recovery
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cell death mechanisms and regulation
- Botulinum Toxin and Related Neurological Disorders
- Dietary Effects on Health
- EEG and Brain-Computer Interfaces
- Radiopharmaceutical Chemistry and Applications
- Lung Cancer Research Studies
- Cytomegalovirus and herpesvirus research
- Hepatitis B Virus Studies
- Muscle Physiology and Disorders
- Gestational Trophoblastic Disease Studies
- Protein purification and stability
- Burkholderia infections and melioidosis
- Adipokines, Inflammation, and Metabolic Diseases
- Signaling Pathways in Disease
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac Ischemia and Reperfusion
- Ion channel regulation and function
- High Altitude and Hypoxia
- Chemical Looping and Thermochemical Processes
- Medical Imaging and Pathology Studies
- Immune Response and Inflammation
Royal Brisbane and Women's Hospital
2022
Tufts Medical Center
2020
Institut Universitaire de Cardiologie et de Pneumologie de Québec
2014
San Diego State University
1998
In the present study, it was shown that physiologically relevant levels of proinflammatory cytokine TNFalpha induced apoptosis in rat cardiomyocytes vitro, as quantified by single cell microgel electrophoresis nuclei ("cardiac comets") well morphological and biochemical criteria. It also stimulated production endogenous second messenger, sphingosine, suggesting sphingolipid involvement TNFalpha-mediated cardiomyocyte apoptosis. Consistent with this hypothesis, sphingosine strongly The...
We describe a method for the purification of normal human liver ferritin by ultrafiltration, gel filtration on Sephacryl S-300, and affinity chromatography DEAE-Affi Gel Blue. The purity obtained was verified immunoelectrophoresis, Ouchterlony immunodiffusion, polyacrylamide electrophoresis, electrofocusing. This rapid yields 32% original ferritin.
Both obesity and aging are associated with dysregulated immune inflammatory responses. There is limited knowledge, however, on differences in the system between young older adults obesity. The goal of this study was to compare circulating cytokines T cell-mediated response women Twenty-three (23–43 years) 21 (60–83 were recruited at Weight Wellness Center Tufts Medical Center. Circulating (CRP, IL-6, IL-1β) ex vivo indicators function compared groups. Older had significantly fewer CD3+,...
Introduction. Melioidosis is an infection that most commonly presents with bacteraemia. Culture-based laboratory methods can result in a significant delay to organism identification. Molecular diagnostic techniques have high sensitivity and rapid time diagnosis. A decreased diagnosis likely improve patient outcomes. Aim. To compare the Panther Fusion automated molecular instrument in-house method for detection of Burkholderia pseudomallei directly from spiked human whole-blood samples....
Chronic obstructive pulmonary disease (COPD) is associated with inflammation, irreversible airflow obstruction and muscular atrophy. Recently, it was shown that atrophy in COPD linked alterations satellite cell function which are the primary myogenic source contributing to skeletal muscle regeneration. The cell‐marker CD34 plays a role movement repair toxin‐induced injury. However, link between expression regeneration has never been studied. Our hypothesis inflammatory hypoxic conditions...