Tianhua Li

ORCID: 0000-0003-3906-4602
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • Electrochemical Analysis and Applications
  • Electrochemical sensors and biosensors
  • Advanced Nanomaterials in Catalysis
  • Advanced Biosensing Techniques and Applications
  • DNA and Nucleic Acid Chemistry
  • Microfluidic and Capillary Electrophoresis Applications
  • SARS-CoV-2 detection and testing
  • Analytical chemistry methods development
  • RNA Interference and Gene Delivery
  • Cancer-related gene regulation
  • Microfluidic and Bio-sensing Technologies
  • Molecular Sensors and Ion Detection
  • Molecular Junctions and Nanostructures
  • Aquaculture disease management and microbiota
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Kruppel-like factors research
  • Cancer-related molecular mechanisms research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Nanocluster Synthesis and Applications
  • Endoplasmic Reticulum Stress and Disease
  • Metal-Organic Frameworks: Synthesis and Applications
  • Venous Thromboembolism Diagnosis and Management
  • RNA regulation and disease

Liaoning University of Traditional Chinese Medicine
2024-2025

Target (United States)
2025

Capital Medical University
2023-2024

Shenyang Pharmaceutical University
2024

Ningbo University
2014-2023

Hebei Medical University
2020-2023

Fourth Hospital of Hebei Medical University
2023

Wenzhou Medical University
2019-2022

Dongyang People's Hospital
2019-2022

Xuan Wu Hospital of the Capital Medical University
2022

Rapid, specific, and on-site detection of virulent foodborne pathogenic strains plays a key role in controlling food safety. In this work, an ultrasensitive specific Phage@DNAzyme signal probe was designed to detect pathogens. The proposed sensing composed the selected phage functionalized DNAzyme, which realized recognition target pathogens at strain level efficient catalysis copper(II) based azide-alkyne cycloaddition (CuAAC) click reaction with fluorescent signal, respectively. As proof...

10.1021/acs.analchem.3c00603 article EN Analytical Chemistry 2023-07-20

A mimicking-enzyme-based colorimetric aptasensor was developed for the detection of kanamycin (KANA) in milk using magnetic loop-DNA-NMOF-Pt (m-L-DNA) probes and catalytic hairpin assembly (CHA)-assisted target recycling signal amplification. The m-L-DNA were constructed via hybridization DNA H1 (containing aptamer sequence) immobilized beads (m-H1) (sDNA, partial with H1) labeled nano Fe-MIL-88NH2-Pt (NMOF-Pt-sDNA). In presence KANA complementary H2, decomposed formed an m-H1/KANA...

10.1021/acs.jafc.7b02139 article EN Journal of Agricultural and Food Chemistry 2017-06-27

An ultrasensitive electrochemiluminescent immunoassay (ECLIA) for aflatoxins M1 (ATM1) in milk using magnetic Fe3O4-graphene oxides (Fe-GO) as the absorbent and antibody-labeled cadmium telluride quantum dots (CdTe QDs) signal tag is presented. Firstly, Fe3O4 nanoparticles were immobilized on GO to fabricate nanocomposites, which used ATM1. Secondly, aflatoxin antibody (primary antibody, ATM1 Ab1), was attached surface of CdTe QDs-carbon nanotubes nanocomposite form (ATM1 Ab1/CdTe-CNT). The...

10.3390/toxins5050865 article EN cc-by Toxins 2013-04-29

An ultrasensitive portable electrochemical immunosensor for human immunodeficiency virus p24 (HIV p24) antigen detection has been developed, whereby the sensitivity was 1000 times higher than that of ELISA method. Firstly, a novel HRP enzyme-antibody copolymer (EV-p24 Ab2) synthesized through an EnVision regent (EV, dextrin amine skeleton anchoring more 100 molecules and 15 anti IgG), then incubated in secondary antibody p24. Secondly, immobilized on gold nanocolloids (AuNPs) to fabricate...

10.3390/ma6041255 article EN Materials 2013-03-25
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