A5101986618- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Epilepsy research and treatment
- Infectious Encephalopathies and Encephalitis
- Salivary Gland Tumors Diagnosis and Treatment
- Fetal and Pediatric Neurological Disorders
- EEG and Brain-Computer Interfaces
- Lung Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Myasthenia Gravis and Thymoma
- Vascular Malformations and Hemangiomas
- Glycogen Storage Diseases and Myoclonus
- Sarcoma Diagnosis and Treatment
- Preterm Birth and Chorioamnionitis
- Neurological and metabolic disorders
- Neuroscience of respiration and sleep
- Ion Transport and Channel Regulation
- Infant Development and Preterm Care
- Tracheal and airway disorders
- Viral Infections and Immunology Research
- Spinal Cord Injury Research
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Hereditary Neurological Disorders
- Organ Transplantation Techniques and Outcomes
Nagoya City University
2007-2025
Nagoya Medical Center
2014-2021
Kurume University
2020
3-D Matrix (Japan)
2019
Dokkyo Medical University
2003-2017
Kyoto Prefectural University of Medicine
2014-2015
Seirei Mikatabara General Hospital
2009-2014
Center for Children
2012
Nagoya University
2012
Mizuho (Japan)
2007
To investigate the association between magnetic resonance imaging (MRI) patterns and motor function, epileptic episodes, IQ or developmental quotient in patients born at term with spastic diplegia.Eighty-six cerebral palsy (CP) diplegia (54 males, 32 females; median age 20 y, range 7-42 y) among 829 CP underwent brain MRI 1990 2008. The clinical findings were analysed retrospectively. Intellectual disability was classified according to Enjoji test Wechsler Intelligence Scale for Children...
Background: Retinopathy of prematurity (ROP) is a serious disease causing blindness in childhood. Gestational age (GA) and birth weight are major factors associated with the development progression ROP, but postnatal systemic inflammation also an important well-known risk factor. Methods: This study retrospectively analyzed relationship between ROP severity using corrected GA (CGA), which reflects intrinsic immaturity infant, rather than days life. Three acute phase reactants (APRs) were...
For patients with infantile epileptic spasms syndrome (IESS) who have achieved remission of (ES), indicators how well the electroencephalographic (EEG) state should be maintained during follow-up are not available. We hypothesized that time course Burden Amplitudes and Epileptiform Discharges (BASED) score after ES is associated relapse. This study aimed to investigate association between relapse BASED scores at initial subsequent period. collected clinical digital EEG data four hospitals...
A mediastinal Mullerian cyst was initially reported as a new category of congenital by Hattori, et al. in 2005. We treated 53-year-old female referred to us with posterior tumor found at the Th5 prevertebral level chest-computed tomography during medical check-up. She had history teratoma, which removed age 35. Chest magnetic resonance imaging revealed homogenous, high-intensity signals T2-weighted images. The lesion resected using thoracoscopic procedure, and histologic immunohistochemical...
The monocytic leukemia zinc finger protein KAT6A (formerly MOZ ) gene is recurrently rearranged by chromosomal translocations in acute myeloid (AML). known to be fused several genes, all of which have histone acetyltransferase (HAT) activity and interact with a number transcription factors as transcriptional coactivator. present study shows that the leucine twenty homeobox ( LEUTX on 19q13 8p11 therapy‐related AML t(8;19)(p11;q13) using cDNA bubble PCR method. fusion transcripts contained 83...
Objective: Intraoperative diagnosis of lymph node (LN) metastasis is critical in lung cancer patients. The one-step nucleic acid amplification (OSNA) assay a novel technique using loop-mediated isothermal method gene amplification. objective this study was to investigate whether the OSNA provides sufficient LN patients.Methods: A total 40 stations were dissected from 20 patients, who had curative lobectomy for cancer. cut halves LNs used pathological diagnosis, and other assay. cytokeratin...
Acute lymphoblastic leukemia (ALL) occasionally develops before or after the onset of Langerhans cell histiocytosis (LCH). The mechanism LCH developing ALL remains unclear; thus clonality during maintenance chemotherapy for T‐cell (T‐ALL) was investigated. T‐ALL and cells tested had same receptor ( TCR ) gamma rearrangement. Mutation analysis NOTCH1 gene revealed 7213C>T (Q2405X) in exon 34 cells, but 5156T>C (I1719T) 27 only T‐ALL. Polymerase chain reaction‐restriction fragment length...
The sudden appearance of hypotension and oliguria without obvious cause following stable circulation respiration in preterm infants is frequent Japan. Such episodes are referred to as late-onset circulatory dysfunction premature (LCD). Volume expanders inotropic agents often ineffective against this condition, whereas i.v. steroids significantly effective. A major problem that cystic periventricular leukomalacia (PVL) develops a few weeks after an episode. aim the present study was clarify...
Catamenial pneumothorax (CP) is a type of spontaneous due to thoracic endometriosis occurring in reproductive women, and usually involves the right side thorax showing diaphragm lesions. For present study, we defined juvenile CP (JCP) as patients with who were 19 years old younger. Institutional findings systematic literature review are presented.We retrospectively enrolled all treated at our institutions from January 2002 June 2013. In addition, conducted search medical published using...
The incidence of late-onset circulatory dysfunction (LCD) premature infants, which is characterized by sudden hypotension and oliguria, has recently increased in Japan. This condition suddenly occurs after several days age without obvious causes preterm infants with stable respiration circulation. Intravenous steroids frequently improve the hypotension. main problem LCD subsequent frequent onset periventricular leukomalacia (PVL), neurological development appears to be worse PVL patients...
Meconium-stained amniotic fluid is observed in approximately 10-15% of all deliveries; however, only 5% neonates with meconium-stained develop meconium aspiration syndrome (MAS). Although foetal distress and subsequent sympathetic stimulation have been considered as the primary upstream events MAS, this clinical complication sometimes occurs due to other pathologies, such intraamniotic inflammation. The aim study was investigate whether incidence MAS associated presence funisitis...
Abstract Background Few population‐based surveys of childhood arterial ischemic stroke ( AIS ) have been conducted in Asian countries. The aim this study was to investigate the clinical features, time diagnosis, and prognosis a cohort Japan. Methods Children aged 29 days–15 years 11 months old, residing Aichi Prefecture Japan with radiologically confirmed during 2010–2014, were identified retrospectively through questionnaires. We analyzed 40 children (23 boys, 17 girls; median age, 7 3...
Abstract Objectives Long‐term adrenocorticotropic therapy (LT‐ACTH), which consisted of 2‐4 weeks daily injections hormone (ACTH) and subsequent months weekly injections, was tried for relapsed West syndrome (WS) or other intractable epilepsies in small case reports. Our aim to explore the efficacy LT‐ACTH preventing WS relapse, as well prevalence its adverse events. Methods This is a retrospective, nationwide, multicenter series patients with who underwent LT‐ACTH. Clinical information...